Clinical trials: Nociception
Colorectal Surgery
Biological and Clinical Underpinnings of Postoperative Pain - Colorectal Surgery
Persistent pain after colorectal surgery remains a significant clinical challenge that can delay recovery, reduce quality of life, and increase long-term healthcare burden.
- Trial name
- BAC-UPP 2 (NCT07219160)
- Volunteers
- 128 people
- Sponsor
- University of Alabama at Birmingham
Postoperative Pain, General Anesthesia
ANI-Guided Anesthetic Desflurane Consumption
General anesthesia requires precise titration of inhaled anesthetics like desflurane and opioids like remifentanil to balance sedation, analgesia, and hemodynamic stability.
- Conditions
- Postoperative Pain, General Anesthesia, Laparoscopic Cholecystectomy
- Trial name
- NCT06982209
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Wonkwang University Hospital
Perioperative Analgesia in Endometriosis
Influence of Intraoperative Nociception Guided Analgesia on Perioperative Total Analgesic Requirement Endometriosis
Adequate analgesia in the perioperative setting is one of the most important pillars of anesthesiology. It is generally understood that poorly managed acute postoperative pain correlates with increased morbidity, prolonged…
- Trial name
- ENDONOL (NCT06732050)
- Testing
- nociception guided treatment
- Where
- Switzerland
- Volunteers
- 125 people
- Sponsor
- Prof Urs Zingg
Perfusion Index
Effect of Pulse Oximeter Device on Measured Perfusion Index Values
The aim of this study is to experimentally determine the effect of pulse oximeters from different manufacturers on measured perfusion index values in healthy subjects at rest and with and without motion artifacts.
- Trial name
- PICOMP (NCT06635018)
- Testing
- Resting conditions, Movement artifacts, Circulation constriction
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- Czech Technical University in Prague
Pain Postoperative, Nociceptive Pain
Intraoperative Electroencephalographic Biomarkers of Postoperative Pain
The goal of this study is to explore whether specific intraoperative EEG signals (brain waves or neuronal electrical activity) are associated with the severity of acute postoperative pain.
- Trial name
- NCT06313320
- Where
- 2 sites in Chile
- Volunteers
- 57 people
- Sponsor
- University of Chile
Pain
Evaluation of NoL Index and ANI After Nociceptive Stimulation at Different Infusion Rates of Remifentanil Infusion
Contrary to "immobility" and, to a lesser extent, to the "hypnosis/unconsciousness" component of general anaesthesia, the monitoring of "analgesia" remains largely elusive, evaluated mainly through poorly sensitive and…
- Trial name
- NCT02602379
- Testing
- Tetanic stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Propofol, Sevoflurane
Comparison of Sevoflurane and Propofol on ANI
The goal of this clinical trial is to compare the effect of sevoflurane and propofol on analgesia nociception index(ANI) in patients undergoing general anesthesia.
- Conditions
- Propofol, Sevoflurane, Analgesia Nociception Index
- Trial name
- NCT06907823
- Testing
- propofol, Sevoflurane
- Volunteers
- 30 people
- Sponsor
- Pusan National University Yangsan Hospital