Clinical trials: Nociceptive Pain
Pain
From ACute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy
Chronic Pain is a wellknown complication after cholecystectomy. Intensity of the pain in the first week after the operation is a predictive factor for the development of chronic pain, but it is unknown whether the risk is more…
- Trial name
- FACTS1 (NCT01553253)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Pain, Acute, Nociceptive Pain
The Nociception Level (NOL) Index for Pain Assessment in the Adult Intensive Care Unit
Assessing pain in the adult intensive care unit (ICU) is challenging because many patients are unable to communicate due to mechanical ventilation and sedation.
- Conditions
- Pain, Acute, Nociceptive Pain, Behavior, Critical Illness
- Trial name
- NOL-ICU (NCT05339737)
- Testing
- Nociception Level (NOL) Index
- Volunteers
- 411 people
- Sponsor
- McGill University
Visceral Pain
Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia
In patients undergoing elective LSCS under subarachnoid block, group BF will receive 0.5% hyperbaric bupivacaine 10mg (2ml) with fentanyl 10 mcg (0.2ml) with total of 2.2 ml and group BD will receive 0.5% hyperbaric bupivacaine…
- Trial name
- NCT06367660
- Testing
- Intrathecal Bupivacaine-Fentanyl and Bupivacaine-Dexmedetomidine
- Volunteers
- 168 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Pain Postoperative, Postoperative Recovery
Application of Transcutaneous Electrical Acupoint Stimulation in Laparoscopic Cholecystectomy
To explore the application of transcutaneous electrical acupoint stimulation combined with transverse abdominis plane block in Laparoscopic cholecystectomy, in order to reduce postoperative pain and promote postoperative recovery.
- Trial name
- NCT05936918
- Testing
- Transcutaneous electrical acupoint stimulatios, Bilateral transverse abdominal plane block
- Volunteers
- 120 people
- Sponsor
- Yangzhou University
Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
Nociceptive Processing in Acute Cutaneous Nerve Entrapment Syndrome
Rationale: Chronic abdominal pain is a frequently occurring condition. Although hardly ever considered, the abdominal wall is the primary cause in 10-30% of cases.
- Trial name
- NCT01920880
- Testing
- Quantitative Sensory Testing analysis
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Analgesia, Nociceptive Pain
Effect of ANI on Intraoperative Opioid Consumption
The aim of the study is to compare the analgesic nociception index (ANI), which is used to determine the dose of analgesic agent needed in the intraoperative period, with the conventional method in patients with erector spinae…
- Conditions
- Analgesia, Nociceptive Pain, Nerve Block, Pain
- Trial name
- NCT05106452
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pain, Postoperative, Nociceptive Pain
Intraoperative Nociception and Postoperative Pain
If the individual patient's pain is assessed and the amount of analgesic needed after surgery is predicted, appropriate injection of pain control and excessive injection of narcotic analgesic can be prevented.
- Conditions
- Pain, Postoperative, Nociceptive Pain, Analgesics
- Trial name
- NCT03761433
- Testing
- SPI group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Pain, Postoperative, Pain
Monitor-Guided Analgesia During General Anesthesia - Part II
This prospective randomized clinical trial evaluates the effects of a monitor-guided opioid analgesia during general anesthesia.
- Conditions
- Pain, Postoperative, Pain, Nociceptive Pain, Opioid Use
- Trial name
- MOGADA-II (NCT03380949)
- Testing
- Opioid administration (remifentanil) in intervention group, Opioid administration (remifentanil) in control group
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia
qNOX Response to Nociceptive Motor Events During Procedural Sedation
The goal of this observational study is to evaluate whether the CONOX monitor can detect pain during sedation in patients undergoing urological procedures.
- Conditions
- Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia, Monitored Anesthesia Care
- Trial name
- MO-NOX (NCT07413848)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Pain, Post Operative, Pain, Acute
Opioid-free Anesthesia in Thyroidectomies
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies.
- Conditions
- Pain, Post Operative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT05243940
- Testing
- dexmedetomidine-ketamine-lidocaine (DKL), remifentanil infusion
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Knee Osteoarthritis
Prediction of Pain After Total Knee Arthroplasty
Despite improvements in treatment, a significant part of patients have severe pain following knee arthroplasty. Preoperative identification of high-risk patients would allow for an intensive individualized analgesic treatment…
- Trial name
- NCT02254499
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Visceral Pain
TMS for the Treatment of Pancreatic Cancer Pain
This is a phase II study that aims to investigate prospectively a new therapy for a cohort of patients with chronic pain attributed to pancreatic cancer.
- Conditions
- Pain, Visceral Pain, Pancreatic Cancer
- Trial name
- NCT00324428
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Neoplasms, Pain
Regional Anesthesia in Breast Surgery
There is a trend that breast surgery can be done with peripheral nerve blockade and intravenous sedation, which reduces the side effects of general anesthesia such as nausea and vomiting, intubation discomfort and postoperative…
- Conditions
- Breast Neoplasms, Pain, Analgesia, Regional Anesthesia
- Trial name
- NCT04629612
- Testing
- Regional anesthesia
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Tissue Pain
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
- Trial name
- OptMeasSkin (NCT06390085)
- Testing
- Soft tissue manipulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia