Clinical trials: Nociceptive Pain
Spinal Cord Injuries, Pain, Neuropathic
Pain Phenotyping in Patients With Neuropathic Pain After Spinal Cord Injury
The development of neuropathic pain is one of the most debilitating sequels after a spinal cord injury (SCI). The overall aim of this study is to investigate potential underlying pathophysiological mechanisms of neuropathic pain…
- Conditions
- Spinal Cord Injuries, Pain, Neuropathic, Nociceptive Pain, Neuropathy
- Trial name
- NCT06443281
- Testing
- Neurophysiology, Cardiovascular test, Experimental pain paradigms
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Inguinal Hernia, Femoral Hernia
Detailed Pain Pattern After Laparoscopic Inguinal Hernia Repair
Pain after laparoscopic groin hernia repair consist of different pain components (overall pain, shoulder pain, incisional pain and visceral pain).
- Trial name
- NCT01105039
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Pain, Postoperative, Opioid Use
Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl
Pain is defined as an unpleasant sensory and emotional conscious experience, associated with actual or potential tissue damage. Nociception is the sympathetic response to noxious stimuli during unconsciousness.
- Conditions
- Pain, Postoperative, Opioid Use, Nociceptive Pain, Postoperative Pain
- Trial name
- NOLFentanyl (NCT03858621)
- Testing
- fentanyl NOL guided
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Victor Contreras, MSN
Pain, Postoperative, Analgesia
Evaluation of Multimodal Analgesia With NOL
The study will include 80 patients undergoing Laparoscopic Cholecystectomy Surgery as part of elective requirements. The study is a single-center, prospective, randomized controlled trial The aim of the study is 1.
- Trial name
- NCT06238830
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Geriatric Pain
Frailty and Chronic Pain Profiles in Patients Aged ≥65 Years
The primary aim of this study is to investigate the relationship between frailty status and pain type, pain localization, and the Geriatric Nutritional Risk Index (GNRI) in individuals aged 65 years and older who present to an…
- Trial name
- F&P (NCT07373860)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Neoplasms, Pain
Regional Anesthesia in Breast Surgery
There is a trend that breast surgery can be done with peripheral nerve blockade and intravenous sedation, which reduces the side effects of general anesthesia such as nausea and vomiting, intubation discomfort and postoperative…
- Conditions
- Breast Neoplasms, Pain, Analgesia, Regional Anesthesia
- Trial name
- NCT04629612
- Testing
- Regional anesthesia
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Postoperative Pain
Preventive Analgesia With Anrikefon in Laparoscopic Cholecystectomy
This study will determine the optimal timing for Anrikefon administration. It will also assess the quality of patient recovery. Laparoscopic cholecystectomy (LC) is a routine surgical procedure.
- Trial name
- ANIPAP (NCT07566663)
- Testing
- Anrikefon for Preventive Analgesia, Anrikefon for bridging analgesia
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Xuanwu Hospital, Beijing
Nociceptive Pain
The Effect of Ongoing Beta-blockers Administration on Analgesic Requirements in the Immediate Perioperative Period.
This study is designed to discover if chronic use of Beta adrenergic receptor blockers affects pain sensation during and after an elective procedure of hip or knee replacement.
- Trial name
- NCT03498898
- Testing
- Chronic use of Beta adrenergic receptor blocker
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spinal Cord Injury, Chronic Pain
Association Between Types of Pain and Motor Activities Physical Activity
This study will investigate the relationships between: (1) physical activity (PA) and types of chronic pain (nociceptive and neuropathic), and (2) virtual reality (VR) and types of chronic pain (nociceptive and neuropathic).
- Trial name
- NCT05236933
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Temple University
Visceral Pain, Postoperative
The Visceral Analgesic Effect of Erector Spinae Plane Block in Laparoscopic Cholecystectomy
The purpose of this study was to investigate the effectiveness of erector spinae plane block on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Trial name
- NCT03767816
- Testing
- Ultrasound guided Rectus sheath block, Ultrasound erector spinae plane block
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Colonoscopy
Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
The total incidence of abdominal pain after colonoscopy is almost 50%. Butorphanol is a mixed opioid receptor agonist-antagonist, which has strong sedative and analgesic effects.
- Trial name
- NCT04477733
- Testing
- Butorphanol Injection, Saline
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Beijing Tiantan Hospital
Kidney Stones
Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be…
- Trial name
- NCT00784472
- Testing
- oxycodone, morphine
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Katja venborg Pedersen
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Chronic Pain, Low Back Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking either WHO Step…
- Trial name
- NCT00983385
- Testing
- Tapentadol PR, Observation period
- Where
- 46 sites in Austria, Croatia and 7 more
- Volunteers
- 208 people
- Sponsor
- Grünenthal GmbH
Coccyx Disorder, Neuropathic Pain
Vitamin D Level and Pain Type in Coccygodynia
Coccygodynia is a painful clinical picture of the sacrococcygeal region.Pain in coccygodynia may be somatic, neuropathic or mixed.
- Conditions
- Coccyx Disorder, Neuropathic Pain, Nociceptive Pain, Vitamin D Deficiency
- Trial name
- NCT05047393
- Testing
- Current blood vitamin D level and painDetect questionairre score will be detected
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cumhuriyet University
Chronic Pain
"MecPain", a New Questionnaire to Assess Chronic Pain Mechanisms.
Validation of a new clinical questionnaire, called 'MecPain', including 12 questions, aimed at better defining the pathophysiological mechanisms of a chronic pain condition.
- Trial name
- MecPain (NCT05713604)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Grenoble
Knee Osteoarthritis
Neurofeedback for Pain Sensitization in Knee Osteoarthritis
The goal of this clinical trial is to learn whether a training method called neurofeedback is safe and practical to use in people with knee osteoarthritis (knee OA).
- Trial name
- NCT07832682
- Testing
- FWR Down-Conditioning Neurofeedback
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Gonarthrosis, Neuropathic Pain, Nociceptive Pain
Functional Brain MRI to Understand Pain Phenotypes in Knee Osteoarthritis
Some people with knee osteoarthritis (gonarthrosis) experience pain differently. In some, the pain is described as "nociceptive" (directly related to the joint), while in others it has "neuropathic" characteristics (related to…
- Trial name
- INDIGO (NCT07668674)
- Testing
- blood sampling, Resting-state functional MRI
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Postoperative, Pain Sensitivity, Postoperative
Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function
Aim of the present study is twofold. First we want to evaluate the effect of mobilization on acute postoperative pain Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total…
- Trial name
- NCT01018277
- Testing
- Mobilization (walking)
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Hvidovre University Hospital
Newborn, Neonatal Screening
Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking
The management of the pain is a constant care concern in neonatal and maternity units. Many studies show an interest in the use of sugar solutions to reduce nociception during painful events in infants.
- Trial name
- BBSUCROSE (NCT02374281)
- Testing
- Glucose sucking, Water sucking, No sucking
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne