Clinical trials: Nodule Solitary Pulmonary
Lung Neoplasms, Lung Cancer
OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
This is a phase 2, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/positron emission tomography imaging based on standard of…
- Trial name
- NCT02872701
- Testing
- OTL38 for Injection, Near infrared camera imaging system, Endoscopic or Thoracic Surgery
- Where
- 6 sites in United States, Netherlands
- Volunteers
- 100 people
- Sponsor
- On Target Laboratories, LLC
Pulmonary Nodule Cm
Sedation of Remazolam Combined With Afentanil in Non-intubated Thoracoscopic Pulmonary Surgery
Non-intubated Thoracoscopic surgery (NITS) is a newly emerging minimally invasive surgical technique in recent years . Compared with traditional intubation general anesthesia, it has the advantages of less trauma, faster recovery…
- Trial name
- R-A NITS (NCT06810843)
- Testing
- Remazolam combined with afentanil for non-intubated thoracoscopic surgery, Propofol combined with afentanil in non-intubated thoracoscopic surgery
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Qianfoshan Hospital
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Pulmonary Nodule, Solitary, Lung Cancer (NSCLC)
Comprehensive Prospective Comparison Of Two Robotic Platforms In Anatomical Lung Resections: Clinical Outcomes And Cost-utility Analysis
The goal is to compare clinical outcomes, hospital costs, and cost-utility in patients undergoing anatomical lung resections with DaVinci Xi vs Versius platforms The main questions it aims to answer are: Do patients that undergo…
- Conditions
- Pulmonary Nodule, Solitary, Lung Cancer (NSCLC), Pulmonary Metastases
- Trial name
- RATS_RYC (NCT07537556)
- Testing
- da Vinci Xi Surgical System, Versius Surgical System
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Lung Cancer, Solitary Pulmonary Nodule
4-[18F]Fluoroglutamine PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
This clinical trial studies positron emission tomography (PET) imaging utilizing 18F-(2S,4R)4-fluoroglutamine, a glutamic acid derivative, to image patients with Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules.
- Conditions
- Lung Cancer, Solitary Pulmonary Nodule, Cigarette Smoking Behavior
- Trial name
- GLN (NCT03568799)
- Testing
- 18F-(2S,4R)4-fluoroglutamine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Lung Cancer (Diagnosis), Nodule, Solitary Pulmonary
Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
The goal of the NIMBLE study is to evaluate blood-based biomarkers for lung cancer risk prediction in patients referred with a lung nodule.
- Trial name
- NIMBLE (NCT07623473)
- Testing
- Blood tests
- Where
- Denmark
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Pulmonary Nodules, Solitary
Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary Nodules
Background Transthoracic computed tomography (CT)-guided procedures are the current gold Standard for obtaining diagnostic biopsies of solitary pulmonary nodules (SPN) in the peripheral lung.
- Trial name
- NAVIGATOR (NCT05383105)
- Testing
- Virtual bronchoscopic navigation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- University Medical Center Groningen
Solitary Pulmonary Nodule, Oncology
18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography
The study objectives are as follows: To determine the safety of trial 18F-2-fluoro-2-deoxy-D-glucose, produced by a new manufacturer, by surveillance for adverse events in patients having Positron Emission Tomography Computed…
- Conditions
- Solitary Pulmonary Nodule, Oncology, 18F-2-fluoro-2-deoxy-D-glucose, Adverse Event
- Trial name
- NCT04615156
- Testing
- 18F-2-fluoro-2-deoxy-D-glucose
- Volunteers
- 10,000 people
- Sponsor
- Eastern Health, Canada
Multiple Pulmonary Nodules
Hybrid Robot-Assisted Percutaneous Ablation and Non-Intubated VATS for Multiple Pulmonary Nodules
The goal of this clinical trial is to evaluate the safety and feasibility of a predefined hybrid treatment strategy in patients with multiple pulmonary nodules who require surgical management of at least one dominant lesion.
- Trial name
- NCT07395362
- Testing
- Hybrid Robot-Assisted Percutaneous Intervention and Non-Intubated Video-Assisted Thoracoscopic Surgery
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
Early Adjuvant Diagnosis of Pulmonary Nodules Based on CTC.
The goal of this observational clinical trial is to evaluate the value of circulating tumor cell detection in the early diagnosis of malignant pulmonary nodule.
- Trial name
- NCT06187935
- Where
- China
- Volunteers
- 172 people
- Sponsor
- China-Japan Friendship Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung China Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- ProLung (NCT02726633)
- Where
- 3 sites in China
- Volunteers
- 500 people
- Sponsor
- Chinese Alliance Against Lung Cancer
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Solitary Pulmonary Nodule, Bronchial Neoplasms
ThoHSpEkt Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With Free-hand SPECT
Title ThoHSpEkt Study Design Pilot Study concerning the technical operative methods and a phase II study concerning the radiopharmaceutical (therapeutic-explorative study with an approved drug in a new indication) Location…
- Trial name
- ThoHSpEkt (NCT02050724)
- Testing
- Radioactive labelling of pulmonary nodules, CT guided radioactive labelling, Electromagnetic guided bronchoscopic radioactive labelling
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Cantonal Hospital of St. Gallen
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial
Lung cancer is currently one of the most common malignant tumors in the world. In recent years, with the popularity of high-resolution CT, more and more early-stage lung cancers have been found.
- Conditions
- Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple, Lung Cancer
- Trial name
- NCT04302350
- Testing
- nitrous oxide
- Where
- 2 sites in China
- Volunteers
- 81 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluation of Lung Nodule Detection With Artificial Intelligence Assisted Computed Tomography in North China
Lung cancer is one of the leading cause of cancer related death in China. Lung cancer screening with low-dose computed tomography was considered as a better approach than radiography.
- Trial name
- NCT03487952
- Testing
- Questionnaire Administration
- Volunteers
- 5,000 people
- Sponsor
- Peking University People's Hospital
Lung Cancer
Ultrathin Bronchoscopy for Solitary Pulmonary Nodules
The evaluation of solitary pulmonary nodules (SPN) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis is endemic.
- Trial name
- Babyscope (NCT02490059)
- Testing
- bronchoscopy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Lung Lesion(s) Requiring Evaluation, Pulmonary Metastasis
Percutaneous Localization: Open-label Registry of Thoracic Surgery
The objectives of this study are to evaluate intraoperative percutaneous lung lesion marking assisted by electromagnetic guided percutaneous navigation and related tools.
- Conditions
- Lung Lesion(s) Requiring Evaluation, Pulmonary Metastasis, Pulmonary Nodule, Solitary, Peripheral Lung Lesions
- Trial name
- PLOTS (NCT04066699)
- Testing
- Percutaneous localization of suspicious lung lesion(s) using electromagnetic navigation and tools.
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Veran Medical Technologies
Solitary Pulmonary Nodule, Coin Lesion, Pulmonary
The Watch the Spot Trial
This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.
- Conditions
- Solitary Pulmonary Nodule, Coin Lesion, Pulmonary, Lung Neoplasms, Carcinoma, Non-small-cell Lung
- Trial name
- WTS (NCT02623712)
- Testing
- More Frequent Surveillance Strategy, Less Frequent Surveillance Strategy
- Where
- United States
- Volunteers
- 34,686 people
- Sponsor
- Kaiser Permanente
AI (Artificial Intelligence), Pulmonary Nodule, Solitary
DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution
This study is a multi-centre prospective observational cohort study recruiting patients with 5-30mm solid and part-solid pulmonary nodules that have been detected on CT chest scans performed as part of routine practice.
- Conditions
- AI (Artificial Intelligence), Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple, Lung Cancer
- Trial name
- DOLCE (NCT05389774)
- Where
- 10 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Pulmonary Nodule, Solitary
The MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules
The purpose of the study is the identification of the efficacy of MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules.
- Trial name
- NCT03790735
- Testing
- FISH
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital