Clinical trials: Noise-Induced Hearing Loss
Hearing Loss, Noise-Induced
Noise-Induced Hearing Loss-Acute Exposure Treatment
The purpose of this study is to assess the safety and efficacy of zonisamide for the treatment of noise-induced hearing loss in adults.
- Trial name
- PINIHL-AET (NCT04768569)
- Testing
- Zonisamide 100Mg Cap
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hearing Loss, Noise-Induced
Does Sound Conditioning Protect Against Temporary Hearing Damage
This research project will contribute to the research surrounding the effect on the ear after noise exposure. This ever-growing field of research has never been more applicable than now with the increase of recreational noise…
- Trial name
- NCT03878875
- Testing
- Session One Test Battery, Session Two Test Battery, Session Three Test Battery
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Hearing Loss, Noise-Induced
Hearing Loss Prevention for Veterans
Hearing loss is the most prevalent service-connected disability in the VA. It causes communication difficulties, which contribute to isolation, frustration and depression.
- Trial name
- HLPP (NCT01038336)
- Testing
- Multimedia Hearing Loss Prevention Program, Hearing Conservation Brochure
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hearing Loss, Noise-Induced
Noise-Induced Hearing Loss-Acute Exposure Treatment (UA)
The purpose of this study is to assess the safety and efficacy of zonisamide (ZNS) for the treatment of noise-induced hearing loss in adults.
- Trial name
- PINIHL-AET (NCT04774250)
- Testing
- Zonisamide 100Mg Cap
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hearing Loss, Sensorineural, Noise Induced Hearing Loss
FX-322 in Adults With Acquired Sensorineural Hearing Loss
This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, single-dose, multicenter study to evaluate the efficacy of FX-322, administered by intratympanic injection, in adults with acquired sensorineural…
- Conditions
- Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
- Trial name
- NCT05086276
- Testing
- FX-322
- Where
- 26 sites in United States
- Volunteers
- 142 people
- Sponsor
- Frequency Therapeutics
Noise-induced Hearing Loss and Tinnitus
TUNE! Teaching the UK About Noise Exposure: A Pilot Study
In 1986 The Medical Research Council estimated that 4 million UK adolescents were at risk of hearing damage from over-exposure to loud music from personal audio players (PAPs), gigs, clubs, pubs and festivals.
- Trial name
- gildeaf1 (NCT00916305)
- Testing
- Modified Audio video, Unmodified audio video
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Noise-induced Hearing Loss
Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)
This prospective study is a randomized, double-blind, placebo-controlled Phase 3 clinical trial of oral D-methionine (D-met) to reduce noise-induced hearing loss (NIHL) and tinnitus.
- Trial name
- NCT02903355
- Testing
- D-methionine
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sensorineural Hearing Loss, Noise Induced Hearing Loss
FX-322 in Adults With Stable Sensorineural Hearing Loss
This is a phase 2a single and repeat dose exploratory efficacy study of intratympanic FX-322 compared to placebo in healthy male and female adults with stable sensorineural hearing loss.
- Conditions
- Sensorineural Hearing Loss, Noise Induced Hearing Loss, Sudden Sensorineural Hearing Loss
- Trial name
- NCT04120116
- Testing
- FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses)
- Where
- 16 sites in United States
- Volunteers
- 95 people
- Sponsor
- Frequency Therapeutics
Hearing Loss
Antioxidation Medication for Noise-induced Hearing Loss
This study will examine whether oral intake of 1200mg N-Acetylcysteine/day will prevent temporary threshold shift in hearing among workers exposed to noise
- Trial name
- NCT00552786
- Testing
- N-acetylcysteine (NAC), glucose
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital