Clinical trials: Noise-induced Hearing Loss
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Hearing Loss, Sensorineural Hearing Loss
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
This study is a single-center, randomized, placebo-controlled, double-blind, single ascending dose escalation study to determine the safety, tolerability, and PK profile of oral administration of HPN-07 in single doses to…
- Conditions
- Hearing Loss, Sensorineural Hearing Loss, Noise-Induced Hearing Loss
- Trial name
- NCT02259595
- Testing
- HPN-07, NAC
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Otologic Pharmaceutics, Inc.
Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction
Hearing/ET/Vestibular in Balloon Pilots
This study looks at whether working as a hot-air balloon pilot-being exposed to burner noise, changes in air pressure/temperature, and vertical acceleration-is linked to changes in hearing, Eustachian tube function, and…
- Conditions
- Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction, Vestibular Disorders, Occupational Exposure
- Trial name
- FLIGHT-EAR (NCT07200310)
- Testing
- Non-invasive audiologic and vestibular assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Noise-induced Hearing Loss
Prevention of Noise-induced Hearing Loss
Noise-induced hearing loss affects an estimated 5% of the worldwide population, with 30-40 million Americans exposed to hazardous sound or noise levels regularly.
- Trial name
- NCT02049073
- Testing
- Zonisamide, Methylprednisolone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cancer, Hearing Loss Ototoxic
The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Hearing-Related Quality of Life
The study will assess the effect of cancer treatments on speech perception in noise, cognition, and hearing-related quality of life by monitoring 200 cancer patients receiving standard care for their underlying malignancy.
- Conditions
- Cancer, Hearing Loss Ototoxic, Cognitive Decline, Quality of Life
- Trial name
- CaSPiN (NCT06551857)
- Testing
- Chemotherapy, chemoradiation, radiation therapy
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hearing Loss, Noise-Induced
The Growing Burden of Hearing-Related Disability.
Hearing loss and tinnitus can affect communication, employment, daily functioning, and long-term disability. This study will examine hearing-related disability claims recorded by the National Insurance Institute of Israel between…
- Trial name
- Hearing (NCT07798687)
- Where
- Israel
- Volunteers
- 150,000 people
- Sponsor
- Assuta Medical Center
Noise Induced Hearing Loss
A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss
SPI-1005 is a novel oral drug that contains a glutathione peroxidase mimetic (ebselen) that will be tested in subjects with a history of NIHL at risk for additional NIHL.
- Trial name
- PANIHL (NCT02779192)
- Testing
- SPI-1005 200mg, SPI-1005 400mg
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sound Pharmaceuticals, Incorporated
Attention Deficit Disorder With Hyperactivity
Study of Attention Deficit/Hyperactivity Disorder Using Transcranial Magnetic Stimulation
Attention deficit/hyperactivity disorder is a condition characterized by a decreased attention span, hyperactivity, and/or impulsiveness inappropriate for a certain age.
- Trial name
- NCT00001915
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tinnitus
Incidence of Tinnitus Amongst Teenagers and Young Adults mp3 Users
The aim of this study is to compare the incidence of tinnitus between mp3 users and non-users, aged between 15 and 30 years old. 100 patients will be recruited in Valença secondary schools.
- Trial name
- NCT01187251
- Where
- 2 sites in Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina de Valenca