Clinical trials: Non Insulin Dependent Diabetes
Diabetes Mellitus, Type 2
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)
This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to semaglutide taken once a week in people with type 2 diabetes.
- Trial name
- COMBINE 2 (NCT05259033)
- Testing
- IcoSema, Semaglutide 1 mg
- Where
- 193 sites in United States, Brazil and 13 more
- Volunteers
- 683 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
Efficacy of Acarbose on Intestinal Microbiome and Incretins of Type 2 Diabetes
This study is aimed to investigate the effect of acarbose on intestinal microbiome and incretins, therefore to explore the new pathways or new targets to treat type 2 diabetes.
- Trial name
- NCT01758471
- Testing
- Glipizide, Acarbose
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Type 1 Diabetes, Type 2 Diabetes
Nurse Telephone Management of Cholesterol in Diabetes
The current project is evaluating the effect of a nurse-administered phone care in diabetes to improve access to care and healthcare delivery.
- Trial name
- NATCHOS (NCT00950963)
- Testing
- Phone Counseling, Standard Clinical Care
- Where
- United States
- Volunteers
- 762 people
- Sponsor
- Denver Health and Hospital Authority
Diabetes Mellitus, Type 2, NAFLD
Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus
Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic SteatoHepatitis (NASH), are a frequent complication of type 2 diabetes and obesity.
- Conditions
- Diabetes Mellitus, Type 2, NAFLD, NASH
- Trial name
- L-FibroT2DM (NCT04232293)
- Testing
- Blood tests
- Where
- 2 sites in France
- Volunteers
- 722 people
- Sponsor
- Nantes University Hospital
Obesity, Diabetes Mellitus, Type 2
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight
This study is open to adults who are at least 18 years old and have a body mass index of 27 kg/m² or more. People can take part if they have type 2 diabetes and if they are currently being treated only with diet and exercise or…
- Trial name
- SYNCHRONIZE™-2 (NCT06066528)
- Testing
- Survodutide
- Where
- 143 sites in United States, Australia and 17 more
- Volunteers
- 755 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2, Hypoglycemia
FreeStyle Libre 2 Discharge Trial
The goal of this clinical trial is to learn about the benefits of using aa Continuous Glucose Monitoring (CGM) system in patients with diabetes following discharge from the hospital.
- Trial name
- NCT05822232
- Testing
- FreeStyle Libre 2 CGM, FreeStyle Libre Pro blinded CGM, FreeStyle Precision Neo blood glucose meter
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Palo Alto Medical Foundation
Diabetes Mellitus, Type 2
A Study of the Effect of LY2189265 on Blood Pressure and Heart Rate in Type 2 Diabetes
The purpose of this study is to assess the effects of 2 doses of LY2189265 on blood pressure and heart rate using 24-hour ambulatory blood pressure monitoring (ABPM), in participants with type 2 diabetes mellitus treated with…
- Trial name
- NCT01149421
- Testing
- LY2189265
- Where
- 76 sites in United States, Argentina and 6 more
- Volunteers
- 755 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus Type 2
Comparative Effectiveness of Cardiovascular Outcomes in New Users of SGLT-2 Inhibitors
CVD-REAL is a multinational, observational cohort study in patients with type 2 diabetes mellitus evaluating the comparative effectiveness of initiating treatment with a sodium-glucose co-transporter-2 (SGLT-2) inhibitor versus…
- Trial name
- CVD-REAL (NCT02993614)
- Where
- 17 sites in United States, Australia and 15 more
- Volunteers
- 99,999 people
- Sponsor
- AstraZeneca
Diabete Type 2, Obesity
Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes
This is a randomized, double-blind, placebo-controlled parallel group study of HU6 and placebo in subjects who are overweight or obese with T2D. The study will be conducted in 4 stages.
- Trial name
- NCT06104358
- Testing
- HU6
- Where
- United States
- Sponsor
- Rivus Pharmaceuticals, Inc.
Type 2 Diabetes, Type 1 Diabetes Mellitus
The Impact of the COVID-19 Pandemic on Diabetes Management
The "CoDiaM study" examines how diabetes management and outcomes are changing during the COVID-19 pandemic and whether these changes are influenced by socio-demographic factors, health literacy, self-efficacy and perceived social…
- Trial name
- CoDiaM (NCT04821921)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 1,503 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cardiovascular Benefits of Zingiber Officinale Roscoe in Patients With Type 2 Diabetes Mellitus Before and After 6 Weeks of add-on Therapy
The Cardiovascular Effects of Ginger (Zingiber Officinale) in Patients With Type II Diabetes Mellitus
The aim of the study was the evaluation of cardiovascular benefits of Zingiber officinale Roscoe in patients with type 2 diabetes mellitus before and after 6 weeks of add-on therapy.
- Trial name
- GINOFF1 (NCT04222738)
- Testing
- GINOFF1
- Where
- Cameroon
- Volunteers
- 21 people
- Sponsor
- Yaounde Central Hospital
Type 2 Diabetes Mellitus
Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
This study evaluates the effect of ginger on NF-KB level in Peripheral Blood Mononuclear Cells in type 2 diabetic patients. Half of patients will receive ginger, while the other half will receive placebo.
- Trial name
- NCT02666807
- Testing
- Ginger
- Volunteers
- 50 people
- Sponsor
- Tehran University of Medical Sciences
Focus Type 2 Diabetes Related Chronic Kidney Disease
Diabetic Kidney Disease: Influence of Exercise Therapy on Physical and Vascular Function.
The general objective is to investigate the effect of a 12 week walking exercise program on vascular endothelial function, arterial stiffness/compliance, and vascular health biomarkers in men and women with pre-dialysis type 2…
- Trial name
- DKD-EXT (NCT02112071)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Minnesota
Diabetes Mellitus, Type 2
Hartmann's Solution and Normal Saline in Type II Diabetes Patients
The purpose of this study is to determine whether perioperative use of Hartmann's solution in type II diabetes patients increases blood glucose level after surgery.
- Trial name
- NCT02305199
- Testing
- Hartmann's solution, Normal saline
- Where
- South Korea
- Sponsor
- Yeungnam University College of Medicine
Metabolic Syndrome, Diabetes Mellitus, Type 2
Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome Pathologies
Original research article entitled Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome by Madeline Gibas for consideration for publication in a clinical journal.
- Conditions
- Metabolic Syndrome, Diabetes Mellitus, Type 2, Pre Diabetes
- Trial name
- NCT03047447
- Testing
- Dietary Ketosis: Regulator of Obesity and Metabolic Syndrome
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bristlecone Behavioral Health, Inc.
Hyperglycemia, Diabetes
Diabetes in the Perioperative Period
High blood glucose levels in surgical patients with and without diabetes are associated with increased risk of medical complications and death.
- Trial name
- NCT00738114
- Where
- United States
- Volunteers
- 3,184 people
- Sponsor
- Emory University
Type 2 Diabetes
Stressors, Coping Methods and Social Support in Diabetic Patients
The increasing prevalence of diabetes brought great burden to health status of the investigators population. It is meaningful to investigate the stressor, stress perceived, social support and coping methods in diabetic population…
- Trial name
- NCT01159184
- Where
- Taiwan
- Volunteers
- 301 people
- Sponsor
- Far Eastern Memorial Hospital
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Type 2 Diabetes
The GRADE Capillary Blood Collection Pilot Study
This pilot study is planned to validate the comparability of HbA1c results obtained from whole blood collection via venous phlebotomy versus a capillary collection of whole blood.
- Trial name
- NCT02388100
- Testing
- Capillary HbA1c collection
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- GRADE Study Group
FDC, Diabetes Mellitus, Type 2
To Compare the Pharmacokinetic Characteristics of the Fixed-dose Combination Compared to the Loose Combination
To compare the safety and pharmacokinetic properties between the administration of DWP16001 and DWC202213 as an individual drug, and the administration of DWJ1563 as a combination drug.
- Trial name
- NCT05737771
- Testing
- DWC202213, DWJ1563, DWP16001
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.