Clinical trials: Non Insulin Dependent Diabetes
Type 2 Diabetes
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Type 2 diabetes mellitus is a chronic metabolic disorder characterized by progressive deterioration in the function of the pancreatic beta-cells, which are the cells that produce and secrete insulin (the hormone primarily…
- Trial name
- NCT01755468
- Testing
- Intermittent insulin therapy, Continuous metformin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Mount Sinai Hospital, Canada
Type 2 Diabetes, Heart Failure
Optimized Glycemic Control in Heart Failure Patients With DM2:"Effect on Left Ventricular Function and Skeletal Muscle"
The investigators wish to investigate wether a more strict diabetic control improves cardiac function, muscle strength, exercise capacity and decreases symptoms.
- Trial name
- HFDM (NCT01213784)
- Testing
- all antidiabetic drugs will be appliable
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Type 2 Diabetes
The Dietary Guidelines 3 Diets Study
The goal of this project is to use a two-stepped study to examine both the adoption of the three dietary patterns as presented by the United States Dietary Guidelines (USDG) and testing of a refined, culturally tailored one-year…
- Trial name
- DG3D (NCT04981847)
- Testing
- Dietary Intervention Meetings
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Diabetes Mellitus, Type 2
Long-term Safety and Efficacy of Empagliflozin as Add on to GLP-1 RA
This is a multi-center, randomised, double-blind, parallel-group, safety and efficacy study of empagliflozin as add-on to GLP-1 RA in Japanese patients with Type 2 Diabetes Mellitus with insufficient glycaemic control
- Trial name
- NCT02589626
- Testing
- empagliflozin 10mg, empagliflozin 25 mg
- Where
- 16 sites in Japan
- Volunteers
- 65 people
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes Mellitus
The Effect of Biscuit Containing Kothala Himbutu on Blood Glucose in Patients With Diabetes. A Randomized Control Study
The investigators intend to conduct a triple blind randomized clinical trial to investigate the effect of a biscuit containing herbal extract, available in the market on the fasting blood sugar control in patients with diabetes…
- Trial name
- NCT02290925
- Testing
- Kothala Himbutu Biscuit
- Where
- Sri Lanka
- Volunteers
- 133 people
- Sponsor
- Rajarata University, Sri Lanka
Non Alcoholic Fatty Liver Disease
Effect of Empagliflozin on Liver Fat Content in Patients With Type 2 Diabetes
Fatty liver disease is an increasingly recognized health problem in patients with type 2 diabetes mellitus (T2DM). Sodium glucose co-transporter type 2 (SGLT-2) inhibitors are a new class of anti-diabetic agents that cause weight…
- Trial name
- E-LIFT (NCT02686476)
- Testing
- Empagliflozin
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Medanta, The Medicity, India
Diabetes, Diabetes Mellitus, Type 2
A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes
This trial is conducted in Japan. The purpose is to compare the safety of once-weekly dosing of semaglutide (0.5 and 1.0 mg) versus sitagliptin (100 mg) once daily, both as monotherapy during 30 weeks of treatment in Japanese…
- Trial name
- SUSTAIN™ (NCT02254291)
- Testing
- semaglutide, sitagliptin
- Where
- 25 sites in Japan
- Volunteers
- 308 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Hypertension
Shiga Microalbuminuria Reduction Trial-2
The purpose of this study is to compare the effects of a direct renin inhibitor (DRI), aliskiren, on the urinary albumin excretion in hypertensive patients with type 2 diabetes under strict blood pressure control with angiotensin…
- Trial name
- NCT01461499
- Testing
- Aliskiren, any angiotensin receptor blockers
- Where
- Japan
- Volunteers
- 237 people
- Sponsor
- Shiga University
Type 2 Diabetes Mellitus, COVID-19
Role of Tele-physical Therapy in Patients With Type 2 Diabetes Mellitus Following COVID-19 Infection.
Diabetes mellitus (DM) is a chronic metabolic disease where the body is unable to metabolize carbohydrates properly either due to a lack of insulin production or abnormal insulin function.
- Trial name
- NCT05599893
- Testing
- Tele physical therapy, Patient educationa and Conventional exercises
- Where
- Saudi Arabia
- Volunteers
- 136 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Diabetes, Fatty Liver
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Background: Vitamin E is an antioxidant that reduces the damaging effects of oxygen in the body. Most American men (90%) and women (96%) do not get enough vitamin E from their diets; however, the amount of vitamin E needed by the…
- Conditions
- Diabetes, Fatty Liver, Obesity, Healthy Volunteers
- Trial name
- NCT00862433
- Testing
- Alpha tocopherol, Vitamin E, Vitamin C
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes Mellitus
Role of Canagliflozin on CD34+ Cells in Patients With Type 2 Diabetes
The investigators hypothesize that Cana may be able to improve number and function of CD34+ endothelial progenitor cells. The investigators also propose that this expected cardiovascular benefit is independent of HbA1C reduction.
- Trial name
- NCT02964585
- Testing
- Canagliflozin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- George Washington University
Type 2 Diabetes Mellitus (T2DM), Psychological Distress
Effectiveness of a Diabetes Self-Management Program Among Ethnic Minority Elderly in Rural Thailand
Type 2 diabetes is a serious health condition that affects many older adults from ethnic minority communities in Northern Thailand.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Psychological Distress, Hyperglycemia
- Trial name
- DSM-EME (NCT07669389)
- Testing
- Diabetes Self-Management Education (DSME) Program, Usual Care
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Taipei Medical University
Type 2 Diabetes Mellitus
Insulin Schemes for Type 2 Diabetes Control
The aim of the study is to determine differences in glycemic control between a basal-bolus scheme insulin and NPH scheme insulin in a population of hospitalized patients with type 2 diabetes in a Noncritical Care Facility in…
- Trial name
- NCT03350984
- Testing
- NPH insulin, Glargine and Lispro insulin
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- Universidad de Guanajuato
Type 2 Diabetes Mellitus, Coronary Atherosclerosis
Assessment With CCTA and MRI in Asymptomatic Patients With Type 2 Diabetes for Detection of Unrecognized Myocardial Scar in Subclinical Coronary Atherosclerosis
The study aimed to prospectively investigate the prevalence of myocardial scar on Dotarem-enhanced Cardiovascular Magnetic Resonance Imaging (MRI) in asymptomatic patients with type-2 Diabetes Mellitus and to assess its…
- Trial name
- ACCREDIT (NCT01254552)
- Testing
- iobitridol, gadoterate meglumine
- Where
- South Korea
- Volunteers
- 351 people
- Sponsor
- Guerbet
Type 2 Diabetes
Phase 2 Study of HEC88473 Injection in Subjects With Type 2 Diabetes Mellitus
This is a multicenter, randomized, parallel, placebo- and active comparator-controlled phase 2 trial to evaluate the efficacy, safety, pharmacokinetics and immunogenicity in subjects with T2DM.
- Trial name
- NCT06148649
- Where
- 2 sites in China
- Volunteers
- 234 people
- Sponsor
- Dongguan HEC Biopharmaceutical R&D Co., Ltd.
Diabetes Type 2
Comparison of Dapagliflozin, Lobeglitazone, and Its Combination in Efficacy and Safety
Diabetes is the most frequently occurring chronic disease along with obesity, hypertension, and hyperlipidemia. The number of patients with diabetes is increasing worldwide.
- Trial name
- Location-F (NCT05915949)
- Testing
- Dapagliflozin 10mg Tab, Lobeglitazone 0.5 mg, Dapagliflozin + Lobeglitazone
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- Seoul National University Bundang Hospital
Type 2 Diabetes
Comprehensive Informatics Framework for Comparative Effectiveness Research (CER) Dissemination
In this project the investigators seek to utilize our experience for developing a comprehensive informatics framework for rapid adaptation and dissemination of Comparative Effectiveness Research (CER) products tailored to…
- Trial name
- iADAPT (NCT01493258)
- Testing
- iCOPE Intervention group
- Where
- 3 sites in United States
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2
A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus
The goal of this clinical trial is to investigate efficacy and safety of an herbal medicinal product of (NW Low-Glu®) in patients with Type 2 Diabetes Mellitus (T2DM).
- Trial name
- NCT06140485
- Testing
- NW Low-Glu®, Metformin
- Volunteers
- 400 people
- Sponsor
- Natural Wellness Egypt
Diabetes Mellitus Type 2
Study of RO6807952 in Patients With Diabetes Mellitus Type 2
This randomized, double-blind, placebo-controlled, multi-center study will evaluate the efficacy and safety of RO6807952 in patients with diabetes mellitus type 2 inadequately controlled with metformin alone.
- Trial name
- NCT01516476
- Testing
- RO6807952, liraglutide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes
To Study Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1656 in Japanese Type 2 Diabetes Mellitus (T2DM) Patients
The purpose of this study is to assess the safety and tolerability of AZD1656 after multiple repeated oral doses in Japanese patients with type 2 diabetes.
- Trial name
- JMAD (NCT00916604)
- Testing
- AZD1656
- Where
- 2 sites in Japan
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
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