Clinical trials: Non Organic Psychosis
Schizophrenia, Schizoaffective Disorder
Cannabidiol Treatment in Patients With Early Psychosis
Cannabidiol (CBD) is a component of herbal cannabis that is present in varying concentrations in cannabis extracts. CBD has been shown to produce central effects including hypnotic, anticonvulsive, anxiolytic and neuroprotective…
- Trial name
- CBD (NCT02504151)
- Testing
- Cannabidiol
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Psychosis, Schizophrenia
Motivational Interviewing for Patients With Acute Psychosis
Psychotic disorders are associated with high levels of distress, limitations in quality of life, and a high risk of chronification for those affected.
- Trial name
- MIA (NCT05911529)
- Testing
- Motivational Interviewing, Supportive conversations
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- Psychiatric University Hospital, Zurich
Psychosis
CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care
In response to the growing need for training on interventions to address first episode psychosis, the Center for Social Innovation (C4) has partnered with experts in Coordinated Specialty Care (CSC) to develop and test CSC…
- Trial name
- CSCOnDemand (NCT02933567)
- Testing
- CSC OnDemand
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Center for Social Innovation, Massachusetts
Psychotic Disorders, Schizophrenia
FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis
The purpose of this study is to compare the efficacy of quetiapine IR, following rapid titration versus conventional titration in patients with acute psychosis
- Conditions
- Psychotic Disorders, Schizophrenia, Bipolar Disorder
- Trial name
- FAST (NCT00486798)
- Testing
- Quetiapine, Rating Scales, Self Assessment Form
- Where
- 13 sites in Sweden
- Sponsor
- AstraZeneca
Psychosis
The Family Cognitive Adaptation Training Manual: A Test of Effectiveness
The purpose of this study is to examine the effectiveness of family cognitive adaptation training, including its impact on functioning and caregiver burden.
- Trial name
- NCT01768000
- Testing
- Family Cognitive Adaptation Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Psychosis, Substance Abuse
Effect Evaluation of Individual Placement and Support (IPS)
Roughly one third of disability pensions issued in Norway are classified as mental and behavioral disorders. The proposed study aims to evaluate the effect of an innovative intervention for returning people with moderate to…
- Conditions
- Psychosis, Substance Abuse, Depression, Anxiety
- Trial name
- NCT01964092
- Testing
- Individual Placement and Support, Ordinary employment schemes
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- NORCE Norwegian Research Centre AS
Schizophrenia
A 20-Year Follow-up of First Episode Psychosis: Longitudinal Effects of Early Treatment Strategies and Relapse
The study aims to address the following questions: 1. Do subgroups defined by early medication choices, relapse, and medication taken over 20 years differ in clinical, cognitive, and functional outcomes? 2.
- Trial name
- NCT07616999
- Where
- China
- Volunteers
- 178 people
- Sponsor
- The University of Hong Kong
Psychosis, Trauma
Social Skills and Emotion Regulation Training "SSERT" for Trauma in Psychosis
This study will investigate if the SSERT (Social Skills and Emotion Regulation Training) intervention is feasible and acceptable in individual with psychotic disorder and a history of trauma.
- Conditions
- Psychosis, Trauma, Emotion Regulation
- Trial name
- SSERT (NCT05100875)
- Testing
- Social Skills and Emotion Regulation Training "SSERT"
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Douglas Mental Health University Institute
Schizophrenia; Psychosis, Cognitive Impairment
Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia
Objective: To determine the efficacy of computer-assisted cognitive remediation (CACR) in patients with chronic schizophrenia in the community settings.
- Conditions
- Schizophrenia; Psychosis, Cognitive Impairment, Executive Function, Randomized Controlled Trial
- Trial name
- NCT04773171
- Testing
- Computer-assisted Cognitive Remediation, Conventional training programmes
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia Disorders
Efficacy & Tolerability of Rigth Unilateral vs. Bitemporal ECT in Schizophrenia in a Psychiatric Hospital in Mexico
Electroconvulsive therapy (ECT) is an established treatment for medication-resistant schizophrenia. There is debate about the best method of electrode placement.
- Trial name
- ULTEC (NCT06972745)
- Testing
- Ultrabrief pulse electroconvulsive therapy, Brief pulse Electroconvulsive therapy
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- Hospital Psiquiátrico Fray Bernardino Álvarez
Psychosis
Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis
Chronic psychosis, including schizophrenia is now viewed as a progressive disorder where cognitive deficits predate the clinical onset.
- Trial name
- PSYCARE (NCT05796401)
- Testing
- Cognitive training, Personalized neuroprotective strategies : Vitamin B12, folinic acid, Omega 3, NAC, Treatment as usual (TAU)
- Where
- 13 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier St Anne
Early Psychosis, Psychotic Disorders
Effects of an Acceptance-based Medication Adherence Therapy for Recent-onset Psychosis
This randomized controlled trial aimed to examine the effectiveness of a 10-session acceptance-based, insight-inducing medication adherence therapy (AIM-AT) program for recent-onset psychosis (in addition to usual care) over a…
- Trial name
- AIM_AT (NCT06192602)
- Testing
- AIM_AT, CPG, TAU
- Where
- Hong Kong
- Volunteers
- 126 people
- Sponsor
- Chinese University of Hong Kong
Psychosis, Mania
Combining mHealth and Nurse-delivered Care to Improve the Outcomes of People With Serious Mental Illness in West Africa
In West Africa, most people with serious mental illness receive care from traditional or faith healers at prayer camps. The stepped-wedge cluster randomized trial aims to evaluate the effectiveness of a dual-pronged intervention…
- Conditions
- Psychosis, Mania, Depression
- Trial name
- NCT05703711
- Testing
- mHealer
- Where
- Ghana
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Washington
Schizophrenia, Schizoaffective Disorder
Database Registry for Neural Network Biomarkers in Psychosis
Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders.
- Trial name
- Imaging (NCT01409109)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia, Psychosis
Influence of Amphetamine-induced Sensitization on Dopamine Synthesis and Release
Patients with schizophrenia show enhanced dopamine synthesis capacity and release, an effect that can be evoked in healthy subjects by repeated amphetamine administration.
- Conditions
- Schizophrenia, Psychosis, Sensitisation
- Trial name
- NCT03223844
- Testing
- Dextroamphetamine Sulfate
- Where
- Austria
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Psychotic Disorder
Mindfulness-Based Family Psychoeducation Intervention for Early Psychosis
A brief Mindfulness-Based Family Psychoeducation programme is developed to reduce the caregiver's stress and to promote young people's recovery.
- Trial name
- NCT03688009
- Testing
- Mindfulness-Based Family Psycho-Education (MBFBE), Family Psycho-Education (FPE)
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Work-Related Condition
Survey of Correction Officers Before and After a Targeted Education Campaign
The investigators will implement a multifaceted Target Education Campaign (TEC) within the three jails about recognizing early psychotic symptoms and referring to the Correctional Health Services.
- Trial name
- COsurvey (NCT05451225)
- Testing
- Targeted Educational Campaign
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Columbia University
Schizophrenia, Schizoaffective Disorder
Role of Anti-Inflammatory Agents in Patients With Schizophrenia
There is some evidence that anti-inflammatory treatment may have beneficial effects in schizophrenia and major depression. Cox-2 inhibitors have been tested in preliminary clinical trials for schizophrenia and depression, showing…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychosis Not Otherwise Specified, Schizophreniform Disorder
- Trial name
- NCT00929955
- Testing
- Ondansetron, Simvastatin
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Pakistan Institute of Living and Learning
First Episode Psychosis
Efficacy and Safety of Paliperidone ER in First Episode Psychosis
The aim of the study is to investigate the efficacy and safety of Paliperidone ER in patients with first episode psychosis.
- Trial name
- NCT01157585
- Testing
- paliperidone ER
- Where
- 12 sites in South Korea
- Volunteers
- 75 people
- Sponsor
- Chonbuk National University Hospital
Schizophrenia
Omega-3 Fatty Acids Efficacy in First-episode of Schizophrenia
There is accumulating experimental evidence to suggest the role of essential fatty acids (EFA) in neuronal migration, pruning and synaptic plasticity.
- Trial name
- OFFER (NCT02210962)
- Testing
- essential fatty acids, olive oil
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Lodz
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