Clinical trials: Non Organic Psychosis
Childhood Schizophrenia, Psychotic Disorder
Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic Disorders
The purpose of this study is to compare the effectiveness and side effects of the drugs clozapine and olanzapine in children and adolescents with schizophrenia and psychoses.
- Conditions
- Childhood Schizophrenia, Psychotic Disorder, Schizophrenia
- Trial name
- NCT00001656
- Testing
- Olanzapine, Clozapine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Mental Health (NIMH)
Device Adherence
Effectiveness of a Digital Platform in Engagement and Prognosis of Patients in an Early Intervention Pychosis Programme
This is a randomised, prospective, controlled trial in which one group (experimental group; GE) receives access to the PIPPEP (Intervention Programme for Early Psychosis) platform in addition to the treatment as usual (TAU) in…
- Trial name
- NCT06556251
- Testing
- PIPPEP App
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia; Psychosis, Cognitive Impairment
A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia
Schizophrenia is a long-lasting and serious mental health disorder that affects about 1% of people worldwide. It can cause symptoms such as hallucinations and delusions (called positive symptoms), confused or disorganized…
- Trial name
- SHINE (NCT07084831)
- Testing
- Xanomeline/trospium
- Where
- 16 sites in Austria, Belgium and 8 more
- Sponsor
- European Group for Research In Schizophrenia
Parkinson's Disease, Psychotic Disorders
Melperone (an Anti-Psychotic) in Patients With Psychosis Associated With Parkinson's Disease
The purpose of this study is to evaluate the safety and efficacy of three target doses of melperone compared to placebo in the treatment of psychosis associated with Parkinson's disease.
- Trial name
- NCT00125138
- Testing
- Melperone HCl
- Where
- 21 sites in United States, India and 1 more
- Volunteers
- 90 people
- Sponsor
- Lundbeck LLC
Psychosis
Measurments Of BBB Breakdown In The Pathogenesis Of Psychiatric Disorders
BBB dysfunction has been indicated in some groups of schizophrenia patients by measuring increased albumin and immunoglobulin (IgG) cerebrospinal fluid (CSF) levels.
- Trial name
- NCT01396850
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Schizophrenia, Schizoaffective Disorder
Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis
This study will assess the effectiveness of an experimental treatment intervention for adolescents and adults who have experienced their first episode of psychosis during the past two years.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder
- Trial name
- NCT01216891
- Testing
- Multi-element, team-oriented treatment
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Clinical High Risk for Psychosis
The Predictive Role of Self-representation in Transition of Individuals at Clinical High Risk for Psychosis
Schizophrenia is one of the most consumptive diseases, which brings great loss to patients and their families, and even to the society.
- Trial name
- NCT04444180
- Testing
- Virtual hand illusion (VHI)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Parkinson's Disease, Psychoses
Aripiprazole in Patients With Psychosis Associated With Parkinson's Disease
The purpose of this clinical research study is to assess the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease.
- Trial name
- NCT00095810
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Alzheimer Disease
Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type
The purpose of this study is to learn if aripiprazole is safe and effective in the treatment of psychosis associated with dementia of the Alzheimer's type.
- Trial name
- NCT00041678
- Testing
- aripiprazole
- Where
- 6 sites in United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Psychosis, Complex Post-Traumatic Stress Disorder
Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum Disorder: PICASSO Trial
Psychosis is a highly distressing mental health condition, affecting up to 3% of the population. Conceptually, it has much in common with complex post-traumatic stress disorder (CPTSD), a recently introduced condition in ICD-11.
- Conditions
- Psychosis, Complex Post-Traumatic Stress Disorder, Schizophrenia
- Trial name
- PICASSO (NCT05281640)
- Testing
- Affect Dysregulation intervention, Negative Self Concept intervention, Disturbed Relationships intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 57 people
- Sponsor
- Edinburgh Napier University
Schizophrenia
Safety Study of ACP-104: To Demonstrate the Safety, Tolerability, and Pharmacokinetics
To determine the safety and tolerability of ACP-104 after oral administration of single doses in comparison with placebo to schizophrenia or other psychotic disorders.
- Trial name
- ACP-104 (NCT00628420)
- Testing
- ACP-104
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Psychosis, Clinical High Risk for Psychosis
Using Mobile Technology to Enhance Early Psychosis Treatment Delivery
This project tests the feasibility of implementing a smartphone application - Ginger.io - in the UC Davis Early Psychosis Program, and investigates whether mobile health technology can improve treatment delivery and outcomes in…
- Trial name
- RWJFGinger (NCT03303456)
- Testing
- Mobile health application - Ginger.io
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Schizophrenia
Brief Culturally Adapted Cognitive Behavior Therapy for Psychosis
While Cognitive behavior therapy for psychosis (CBTp) is now established as an effective and evidence based therapy for psychotic illnesses in the west and is recommended by the national organizations both in Europe and in the…
- Trial name
- NCT01876056
- Testing
- Brief CaCBTp
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Psychosis, Schizophrenia
Exercise Target Brain Oscillations in Psychosis
Previous studies have shown that cardiorespiratory fitness (how well the heart and lungs are able to function during physical activity) is often reduced in people with psychosis.
- Conditions
- Psychosis, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT05338424
- Testing
- Sprint Interval Training (SIT)
- Where
- United States
- Sponsor
- University of Minnesota
Schizophrenia, Affective Disorders, Psychotic
Self-Management and Recovery Technology Psychosocial Intervention Trial
This project is a component of a broader research program referred to as "Self-Management and Recovery Technology (SMART): Use of online technology to promote self-management and recovery in people with psychosis", which has been…
- Conditions
- Schizophrenia, Affective Disorders, Psychotic, Psychotic Disorders
- Trial name
- SMARTTherapy (NCT02474524)
- Testing
- Health intervention, Social intervention
- Where
- 10 sites in Australia
- Volunteers
- 148 people
- Sponsor
- Swinburne University of Technology
Psychosis; Schizophrenia-Like
Non-Pharmacological Treatment of Psychosis
The objectives of the project are to investigate feasibility, safety, and health-related outcomes in patients with psychosis who choose not to use antipsychotic drugs (APs).
- Trial name
- NCT04051775
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
Schizophrenia, Schizoaffective Disorder
An Integrated Program for the Treatment of First Episode of Psychosis
The purpose of this study is to determine how services should be provided to reduce symptoms and improve life functioning for adolescents and adults who have been recently diagnosed with schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Brief Psychotic Disorder
- Trial name
- RAISE ETP (NCT01321177)
- Testing
- Integrated Treatment, Community Care
- Where
- 33 sites in United States
- Volunteers
- 404 people
- Sponsor
- Northwell Health
Psychosis
Mindfulness RCT for Early Psychosis
Depressive mood and anxiety are prevalent in patients suffering from early psychosis. Treatments focused on these dimensions are rarely seen.
- Trial name
- MBIp (NCT02244970)
- Testing
- Mindfulness, Psychoeducation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Psychosis, Schizophrenia
Targeting Individual Alpha Frequencies to Enhance Perceptual Timing
This is a single-blind randomized within-subject crossover design study that will be conducted in 2 phases. In Phase 1, up to 50 participants, after signing informed consent and determining eligibility, will undergo a baseline…
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder
- Trial name
- NCT04856657
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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