Clinical trials: Non Organic Psychosis
Clinical High Risk for Psychosis (CHR)
Digital Dialectical Behavioural Therapy (d-DBT) for Youth at Clinical High Risk (CHR) for Psychosis
This study examines the feasibility and acceptability of a digital dialectical behavior therapy (d-DBT) intervention for youth at clinical high risk (CHR) for psychosis.
- Trial name
- NCT06928935
- Testing
- d-DBT
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia and Schizophrenia Spectrum Psychosis
Feeling Safe Study
The goal of this study is to assess the acceptability and satisfaction with the psychological intervention Sentirnos Seguros (Feeling Safe) in people with psychotic disorders and positive delusional symptoms.
- Trial name
- NCT07234708
- Testing
- Sentirnos Seguros
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Psychosis
Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis
The proposed pilot study is a randomized controlled study to assess effectiveness of transcranial direct current stimulation (tDCS) to enhance cognitive remediation therapy in patients with psychotic disorders. tDCS.
- Trial name
- NCT02085421
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Parkinson's Disease Psychosis
A Study of the Safety and Efficacy of Pimavanserin in Patients With Parkinson's Disease Psychosis
The purpose of this study is to evaluate the safety and efficacy of 34 mg pimavanserin compared to placebo in patients with Parkinson's disease psychosis (PDP).
- Trial name
- NCT06068465
- Testing
- pimavanserin tartrate
- Where
- 60 sites in China
- Volunteers
- 248 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Schizophrenia, Psychosis
To Rescue Cognition With Valaciclovir
This is a one-week, randomized, double blind add-on study of valaciclovir versus placebo in 24 clinical patients with Schizophrenia according to DSM IV, currently experiencing psychosis as is defined by the positive items of the…
- Trial name
- NCT01364792
- Testing
- Valaciclovir
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- University Medical Center Groningen
First Episode Psychosis
Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes
The goal if the project is to develop a learning health network devoted to the treatment of first episode psychosis.
- Trial name
- ESPRITO (NCT04004364)
- Testing
- Coordinated Specialty Care (CSC)
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Northwell Health
Family Members
Family Peer Navigator for Early Psychosis for Black Families
Building upon formative research, this mixed methods study will be conducted in three phases to develop, refine, and pilot-test a multi-component Family Peer Navigator model designed to increase access to and initial engagement…
- Trial name
- NCT05284721
- Testing
- Family Peer Navigator for Early Psychosis, Care Coordination
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Washington State University
Acceptance and Commitment Therapy, Psychotic Disorders
Acceptance and Commitment Therapy (ACT) in Early Psychosis Patients
This study is to examine the effect of Acceptance and Commitment Therapy applied to patients in early psychosis patients on psychotic symptoms and functionality levels.
- Conditions
- Acceptance and Commitment Therapy, Psychotic Disorders, Psychiatric Nursing
- Trial name
- NCT05210816
- Testing
- Acceptance and Commitment Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Schizophrenia, Schizotypal Disorder
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
The OPUS YOUNG (OY) study investigates the efficacy of early intervention service versus treatment as usual (TAU) for adolescents aged 12-17 years with a first-episode psychosis.
- Conditions
- Schizophrenia, Schizotypal Disorder, Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
- Trial name
- OPUS-YOUNG (NCT04916626)
- Testing
- OPUS YOUNG, Treatment as Usual
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Schizophrenia, Alzheimer's Disease Psychosis
A Study Assessing the Safety and Tolerability of LY03020 in Chinese Healthy Subjects
This is a single-center, randomized, double-blind, placebo-controlled, ascending single oral dose study to assess the safety, tolerability, and pharmacokinetics of LY03020 in Chinese healthy adult subjects.
- Trial name
- NCT06556966
- Testing
- LY03020
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
First Episode Psychosis
First Episode Psychosis and Pathway to Care in Nordland
First episode psychosis patients often experiences treatment delay. This reduces their prospects for recovery and makes unnecessary burdens for them and their carers.
- Trial name
- NCT01753284
- Volunteers
- 40 people
- Sponsor
- Nordlandssykehuset HF
Postpartum Depression, Major Depressive Disorder
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
The project aimed at identifying neuropsychobiological signatures of pharmacological sex-steroid hormone manipulations in healthy women as a risk model for depression.
- Conditions
- Postpartum Depression, Major Depressive Disorder, Postpartum Psychosis, Menopause
- Trial name
- GnRHa (NCT02661789)
- Testing
- Goserelin 3.6 mg implant
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Healthy Volunteers, Modeling Psychosis
Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study
The study evaluates the gene-environment interaction of the COMT-genotype on the effects of the phytocannabinoids delta-9-tetrahydrocannabinol, cannabidiol or a combination of both on induction of psychotic symptoms…
- Trial name
- NCT02492074
- Testing
- Delta-9-tetrahydrocannabinol, Cannabidiol
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Schizophrenia, Psychosis
Neuroimaging Studies of Neurophysiological Phenotypes in Schizophrenia
Background: Eye tracking, the ability to focus on and follow a moving target with the eyes, is often difficult for people who have schizophrenia.
- Trial name
- NCT01036568
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Psychosis, Schizophrenia
The BC Psychosis Program Biobank and Database for Genetic Polymorphisms and Their Associations With Psychosis Disorder
The purpose of this study is to determine if candidate polymorphisms in brain-derived neurotrophic factor (BDNF) and catechol-o-methyl transferase (COMT) are predictive of psychosis disorder severity, symptomology, and resolution…
- Trial name
- BCPP BIODA (NCT02322918)
- Testing
- Blood samples for whole genomic/transcriptomic sequencing
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
Psychoses
Adapting a Socio-cognitive Intervention to Early Psychosis Services
Social cognition (SC) is a broad term used to describe abilities we use to process/interpret emotional cues, others' and own thoughts/feelings.
- Trial name
- NCT07102784
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- King's College London
First-episode Psychosis
Biomarkers Predictive of Thymic Evolution and Therapeutic Response at 2 Years in Patients With a First Psychotic Episode
Psychosis is a severe, common, and disabling psychological disorder. An epidemiological study conducted in England reported an incidence of 34 new cases per 100,000 person-years, with a peak between 16 and 19 years of age.
- Trial name
- PEPAMARKER (NCT05384392)
- Testing
- Recorded interview, Clinical scales, Blood sample
- Where
- 5 sites in France
- Volunteers
- 217 people
- Sponsor
- University Hospital, Brest
Work-Related Condition
Survey of Correction Officers Before and After a Targeted Education Campaign
The investigators will implement a multifaceted Target Education Campaign (TEC) within the three jails about recognizing early psychotic symptoms and referring to the Correctional Health Services.
- Trial name
- COsurvey (NCT05451225)
- Testing
- Targeted Educational Campaign
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Columbia University
Schizophrenia Schizoaffective
Personalised Cognitive Remediation Therapy (pCRT)
Cognitive deficits have been shown to have negative impact on social functioning and functional goals such as ability to work and perform daily tasks in people with schizophrenia.
- Trial name
- pCRT (NCT03461432)
- Testing
- Cognitive Remediation Therapy
- Volunteers
- 15 people
- Sponsor
- King's College London
Schizophrenia, Schizoaffective Disorder
Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia
This a randomized double-blind placebo controlled trial which aims to determine the beneficial effects of minocycline augmentation to clozapine in partial responders to Treatment Resistant Schizophrenia (TRS).
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT02533232
- Testing
- Minocycline
- Where
- 4 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Institute of Living and Learning
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.