Clinical trials: Non Organic Psychosis
Healthy Subjects, Schizophrenia
Studies of Frontal Lobe Brain Functioning in Schizophrenia
The purpose of this study is to use brain imaging technology to investigate the role of the frontal lobe of the brain in the thinking of individuals with schizophrenia and other neuropsychiatric disorders and healthy volunteers.
- Conditions
- Healthy Subjects, Schizophrenia, Parkinson Disease
- Trial name
- NCT00001258
- Testing
- Oxygen-15 Water
- Where
- United States
- Volunteers
- 1,039 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia
Evaluation of the Antipsychotic Efficacy of Cannabidiol in Acute Schizophrenic Psychosis
A controlled, randomized study on the treatment of schizophrenic psychosis with cannabidiol, a phytocannabinoid is performed. This approach is based upon recent findings indicating that the human endogenous cannabinoid system is…
- Trial name
- CBD-CT1 (NCT00628290)
- Testing
- Cannabidiol, Amisulpride
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Cologne
Psychosis, Agitation
Ziprasidone vs Standard Therapy for Agitated Patients in the ED
The primary objective is to determine if ziprasidone is superior to standard therapies in the emergency department treatment of the acutely agitated patient.
- Conditions
- Psychosis, Agitation, Delirium
- Trial name
- NCT00786318
- Testing
- ziprasidone, Standard therapy
- Where
- United States
- Sponsor
- George Washington University
Psychosis
Effectiveness of Meta-Cognitive Training (EMC) in People With Psychosis of Brief Evolution.
The purpose of this study is to assess the effectiveness of Meta-Cognitive Training (EMC) in people with a brief psychotic disorder, especially positive symptoms.
- Trial name
- NCT02340559
- Testing
- Meta-cognitive Training, Psychoeducational group
- Volunteers
- 122 people
- Sponsor
- Fundació Sant Joan de Déu
Psychosis, Schizophrenia
The Evaluation of the Use of a New Physical Health Plan
People suffering from psychotic illnesses (e.g. schizophrenia) have poorer physical health than the general population. The reasons include a lack of service user motivation to attend physical health checks and the tendency of…
- Trial name
- NCT03178279
- Testing
- Physical Health Plan
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- King's College London
Psychosis, Suicide Prevention
Cognitive AppRoaches to coMbatting Suicidality
This is a randomised controlled trial which investigates the effectiveness of CARMS (Cognitive AppRoaches to coMbatting Suicidality) therapy in reducing suicidal thoughts and how well CARMS works in practice within the NHS.
- Conditions
- Psychosis, Suicide Prevention, Suicidality
- Trial name
- CARMS (NCT03114917)
- Testing
- Cognitive AppRoaches to coMbatting Suicidality (CARMS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 329 people
- Sponsor
- University of Manchester
First Episode Psychosis
Socially Inappropriate Behaviour in People With First Episode Psychosis: A Caregivers' Perspective
Social impairment is one of the core symptoms in first episode psychosis (FEP). Despite negative symptoms and social cognition impairment found in patient suffering from FEP, clinicians occasionally identified socially…
- Trial name
- NCT03501160
- Testing
- Face-to face semi-structured in-depth interview
- Where
- 2 sites in Hong Kong
- Volunteers
- 8 people
- Sponsor
- Chinese University of Hong Kong
Schizophrenia
Melatonin for Prevention of Metabolic Side Effects of Olanzapine
The purpose of this study is to determine whether melatonin can prevent metabolic side effects of olanzapine such as weight gain, elevated glucose concentrations and lipid abnormalities.
- Trial name
- NCT01593774
- Testing
- Melatonin
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Guilan University of Medical Sciences
First Episode Psychosis, Schizophrenia, Childhood
Early Psychosis Intervention - Spreading Evidence-based Treatment
Implementation of 'NAVIGATE' in Ontario aims to help youth and emerging adults suffering from a first episode of psychosis. Although Ontario already has early psychosis intervention programs, the team's recent work has identified…
- Conditions
- First Episode Psychosis, Schizophrenia, Childhood, Psychosis, Schizophrenia
- Trial name
- EPI-SET (NCT03919760)
- Testing
- NAVIGATE, Treatment as Usual
- Where
- 6 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Schizophreniform Disorder
Integrated Metacognitive Therapy in First Episode Psychosis
Insight, or lack of illness awareness, is a prominent and pressing clinical concern in the treatment and recovery of patients with psychotic disorders.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Trial name
- IMT (NCT02131116)
- Testing
- Integrated Metacognitive Therapy, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Psychosis
Effectiveness of Cognitive Remediation in a Supported Education Setting
The purpose of this study is to determine whether cognitive remediation as an adjunct to supported education, will result in improved cognitive functioning, symptoms, and performance in academic domains for persons with psychosis…
- Trial name
- NCT01492439
- Testing
- Cognitive Remediation, Supported Education
- Where
- 2 sites in Canada
- Volunteers
- 37 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Schizoaffective Disorder
Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia
This a randomized double-blind placebo controlled trial which aims to determine the beneficial effects of minocycline augmentation to clozapine in partial responders to Treatment Resistant Schizophrenia (TRS).
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT02533232
- Testing
- Minocycline
- Where
- 4 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Institute of Living and Learning
Psychosis
Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performance in Psychosis Risk
Background Psychosis is a mental health condition that affects around 3 in 100 people in their lifetime. Most treatments for psychosis target a brain chemical called dopamine but they don't work for everyone and don't address…
- Trial name
- LEVHIPPRO (NCT06224530)
- Testing
- Levetiracetam
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- King's College London
Psychosis; Schizophrenia-Like
Non-Pharmacological Treatment of Psychosis
The objectives of the project are to investigate feasibility, safety, and health-related outcomes in patients with psychosis who choose not to use antipsychotic drugs (APs).
- Trial name
- NCT04051775
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Haukeland University Hospital
At-risk Mental States, First Episode Psychosis (FEP)
The Influence of Tennis in Early Intervention
This study involves two groups of participants: one participating in an intervention focused on self-esteem-and thus primarily psychological-and the other on self-esteem and tennis-and thus involving physical activity.
- Trial name
- ITIP (NCT07633899)
- Testing
- Tennis ( physical activity), Self-esteem program
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Esquirol
Schizophrenia; Psychosis, Persecutory Delusion
Cognitive Behavioral Therapy (CBT) Study Evaluating the Updating of Persecutory Beliefs
The purpose of this study is to examine how Bayesian belief updating changes throughout psychotherapeutic treatment for persecutory delusions.
- Trial name
- NCT04748679
- Testing
- Worry Intervention, Befriending
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Vanderbilt University Medical Center
Clozapine, Parkinson's Disease (PD)
Clozapine-related Immunodeficiency in Parkinsons Disease
Clozapine is a second generation antipsychotic drug used in psychiatry to treat schizophrenia, affective disorders or certain symptoms of dementia.
- Conditions
- Clozapine, Parkinson's Disease (PD), Immunodeficiency, Psychosis
- Trial name
- CLOZIDPD (NCT06634641)
- Testing
- blood test
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Psychosis
A Study of the Effectiveness of Cognitive Adaptation Training in Early Intervention for Psychosis
The proposed study will involve a randomized trial of Cognitive Adaptation Training (CAT) for early intervention as compared against an active control in which Action Based Cognitive Remediation (ABCR) will be applied.
- Trial name
- NCT02430935
- Testing
- Cognitive Adaptation Training, Action Based Cognitive Remediation
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Centre for Addiction and Mental Health
Comparing Clinical Profile and Prognosis of Schizophrenia Versus Methamphetamine Induced Psychosis, SCHIZOPHRENIA
This Hospital-based Observational Study Employed a Study Will be Conducted in Sohag University Hospital Clinics Aiming to Ensure Cases Presented With Psychosis in Two Phases to Differentiate Into Two Groups a Case of Schizophrenia or a Case of Methamphetamine Induced Psychosis.
This hospital-based observational study employed prospective follow up study will be conducted in sohag university hospital clinics aiming to ensure cases presented with psychosis in two phases to differentiate into 2 groups (a…
- Conditions
- Comparing Clinical Profile and Prognosis of Schizophrenia Versus Methamphetamine Induced Psychosis, SCHIZOPHRENIA, Methamphetamine Induced Psychosis
- Trial name
- NCT07184710
- Volunteers
- 200 people
- Sponsor
- Sohag University
Schizophrenia, Schizoaffective Disorder
Enhancing Veteran-Clinical Collaboration in VA PRRCs
Over 60% of Veterans with serious mental illness have a service-connected disability that impairs their ability to work, go to school, and/or have successful personal lives.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder, Bipolar Disorder
- Trial name
- EVCC VPRRC (NCT06898879)
- Testing
- Collaborative Decision Skills Training, Leveling Up
- Where
- 3 sites in United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
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