Clinical trials: Non-Diabetic
Diabetes, Atherothrombosis
Atherothrombosis Markers in Diabetics
Intraplaque hemorrhage is the driving force of atherothrombotic plaque vulnerability to rupture and associated clinical complications.
- Conditions
- Diabetes, Atherothrombosis, Cardiovascular Disease
- Trial name
- MADI (NCT02898467)
- Testing
- diabetics, non-diabetics
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Diabetic Macular Edema, Neovascular (Wet) Age-Related Macular Degeneration
Effectiveness of Multidisciplinary Protocolised Interventions on IVT Non-adherence Rates
The purpose of this research study is to test whether a personalised care approach improves adherence compared to standard care.
- Conditions
- Diabetic Macular Edema, Neovascular (Wet) Age-Related Macular Degeneration, Intravitreal Injection
- Trial name
- ADHERE (NCT07567898)
- Testing
- multidisciplinary protocolized intervention (MPI), Routine medical care & monitoring
- Volunteers
- 200 people
- Sponsor
- Singapore Eye Research Institute
Diabetic Foot Ulcer
Surgical Offloading Procedures for Diabetic Foot Ulcers
100 consenting subjects with Texas grade 1a diabetic foot ulcers will be randomized to surgical offloading or non-operative offloading.
- Trial name
- NCT03414216
- Testing
- Group 1 early offloading surgery, Group 2 - off-loading in fiberglass cast
- Volunteers
- 100 people
- Sponsor
- Assaf Harofeh MC
Diabetes, Diabetic Foot Ulcer
ExpressGraft-C9T1 Skin Tissue as a Treatment of Diabetic Foot Ulcers
This study is designed as a prospective, open-label trial focused on assessing the safety and tolerability of ExpressGraft-C9T1 skin tissue in the treatment of diabetic foot ulcers (DFU).
- Conditions
- Diabetes, Diabetic Foot Ulcer, Non-healing Wound
- Trial name
- NCT02657876
- Testing
- ExpressGraft-C9T1 Skin Tissue
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Acute Viral Hepatitis, Diabetes Mellitus
Acute Viral Hepatitis and Diabetes Mellitus
It has been observed that several of patients having prolonged or complicated course of acute viral hepatitis have underlying diabetes.
- Trial name
- NCT00689546
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences
Type 2 Diabetes
Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects
Type 2 diabetes (T2D) could modulate CYP450 activities involved in drug-metabolism and cardiovascular homeostasis. We propose to carry out, for the first time, a comprehensive characterization of the effects of T2D on the…
- Trial name
- NCT02291666
- Testing
- CRCHUM-MT cocktail
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Tuberculosis
BCG Revaccination Study in Diabetic and Non-Diabetic Adults
The purpose of this study is to: 1. explore whether investigators can make BCG more effective by giving it in a different way. For this, aerosol inhaled BCG will be compared against the conventional BCG injection. 2.
- Trial name
- NCT06246851
- Testing
- BCG Danish
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Proliferative Diabetic Retinopathy
Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy
The RECOVERY trial will assess the safety and tolerability of 2 mg intravitreal aflibercept injections (IAI) given monthly (Q4WK) or every 12 weeks (Q12WK) for the treatment of retinal capillary non-perfusion (RNP) associated…
- Trial name
- RECOVERY (NCT02863354)
- Testing
- Aflibercept
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- Charles C Wykoff, PhD, MD
Inflammation, Oxidative Stress
The Influence of Cessation of Pomegranate Juice Intake on Inflammation and Oxidative Stress Markers and Glucose Control in Diabetic and Non Diabetic Chronic Hemodialysis Patients
The current study will investigate chronic hemodialysis patients who were treated in our unit with pomegranate juice intake for 1 year - compared to a control group.
- Trial name
- NCT01033435
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 49 people
- Sponsor
- Western Galilee Hospital-Nahariya
Type 2 Diabetes Mellitus, Periodontitis
Oral Health Policy for Patients With Type 2 Diabetes Mellitus in Chile: A Microsimulation Model Based on Real-world Data
The goal of this study is to evaluate the cost-effectiveness of the current proposal and different decision-making scenarios of periodontal care coverage increases for patients with T2DM in Chile.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, Diabetic Complication, Dental Care
- Trial name
- NCT05809817
- Testing
- Periodontal treatment
- Where
- 2 sites in Chile
- Volunteers
- 135 people
- Sponsor
- University of Chile
Diabetes Mellitus Type 2, Hyperglycemia
Efficacy of GLP-1 Infusion in Comparison to an Insulin Infusion Protocol to Reach Normoglycemia Type 2 Diabetic Patients
The aim of the investigators study was to compare for the first time efficacy and safety of intravenously administered GLP-1 with an established intravenous insulin regimen in hyperglycaemic type 2 diabetic patients.
- Trial name
- NCT00859079
- Testing
- GLP-1, Human regular insulin intravenously
- Where
- Austria
- Volunteers
- 8 people
- Sponsor
- Medical University of Graz
Pre Diabetic, Hyperglycaemia (Non Diabetic)
Diabetes Prevention by Group Intervention and CGM Use in Pre-diabetic Adults
This study is being done to find better ways to help people with prediabetes prevent or delay the development of type 2 diabetes.
- Trial name
- CGM (NCT07543068)
- Testing
- Combines group sessions and CGM-based behavioral feedback
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Sam Houston State University
Healthy Volunteers, Erythritol
SUVY VerSus SAccharose (SUVISA)
Sugar substitutes are increasingly used to reduce sugar intake. SÜVY is a food ingredient combining erythritol and polydextrose.
- Trial name
- SUVISA (NCT07901491)
- Testing
- SÜVY, Sucrose
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Minerais SAS
Non-diabetic Chronic Kidney Disease
Effect of Chinese Herbal Medicine on Kidney Function in Non-Diabetic CKD
This study is a randomized controlled pilot trial designed to evaluate the effects and safety of a traditional Chinese medicine formula (CKD-1) as an add-on therapy to standard treatment in patients with stage 3-4 non-diabetic…
- Trial name
- NCT07657338
- Testing
- Chinese herbal formula CKD-1
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- China Medical University Hospital
Bariatric Surgery, Obese
Comparative Evaluation of the Evolution of Arterial and Microcirculatory Endothelial Function in Obese Patients With Type-2 Diabetes Versus Non-diabetic Obese Patients After a First Bariatric Surgery
The weight reduction obtained after a first bariatric surgery would improve the vascular (correction of endothelial dysfunction, improvement of arterial wall compliance and evolution of the atherothrombotic process) and…
- Conditions
- Bariatric Surgery, Obese, Type2 Diabetes
- Trial name
- BariVaDia (NCT03636243)
- Testing
- Vascularly biological assessment, Analysis of vasomotor endothelial function, Analysis of arterial compliance
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Foot Ulcers
dHACM In the Treatment of Diabetic Foot Ulcers
A single-centered, non-randomized study with approximately 20 subjects that will be seen for up to 12 weeks, each receiving the EpiFix plus standard of care. Safety and effectiveness will be monitored throughout the study.
- Trial name
- NCT02587104
- Testing
- EpiFix
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- MiMedx Group, Inc.
Non Small Cell Lung Cancer
Influence of the Use of the Diabetic Drug Metformin on the Overall Survival and Treatment-related Toxicity in Advanced Stage Non-small Cell Lung Cancer Patients.
There are preliminary data suggesting that patients suffering from non-insulin-dependent diabetes mellitus, treated with metformin, have improved local tumor control.
- Trial name
- Metformin (NCT02109549)
- Where
- 3 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Maastricht Radiation Oncology
Sepsis, Septic Shock
Sepsis in ICU:Causes and Outcomes of Sepsis in Diabetics Versus Non Diabetics in Assiut University Hospital
Clarify different causes of sepsis in patients admitted to ICU . as well asCompare causes and outcomes of sepsis between diabetics versus non diabetics .
- Trial name
- NCT04015752
- Testing
- culture from infected site
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2
Diabetes Visual Function Supplement Study
This study will evaluate the effects of a novel multi-component dietary supplement on the visual function and retinal structure of patients with diabetes with both no diabetic retinopathy and mild to moderate diabetic…
- Conditions
- Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Non-proliferative Diabetic Retinopathy
- Trial name
- DiVFuSS (NCT01646047)
- Testing
- multi-component nutritional supplement capsules, multi-component dietary supplement
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- ZeaVision, LLC
Sodium Glucose Co-Transporter 2 Inhibitors, Estimated Glomerular Filtration Rate
Sodium Glucose Co-Transporter 2 Inhibitors on Estimated Glomerular Filtration Rate in Diabetic Versus Non-Diabetic Chronic Kidney Disease Patients
The work aimed to compare the effects of Sodium-glucose co-transporter-2 (SGLT2) inhibitors on glomerular filtration rate (GFR) in patients with diabetic chronic kidney disease (CKD) and non-diabetic CKD.
- Conditions
- Sodium Glucose Co-Transporter 2 Inhibitors, Estimated Glomerular Filtration Rate, Diabetes, Chronic Kidney Disease
- Trial name
- NCT07302464
- Testing
- Sodium Glucose Co-Transporter 2 Inhibitors
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University