Clinical trials: Non-Insulin Dependent
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Diabetes
This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00659295)
- Testing
- insulin detemir
- Where
- 13 sites in Belgium, Czechia and 11 more
- Volunteers
- 51,170 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Non-Insulin-Dependent
MK-0941 Multiple Dose Study in Japanese Patients With Type 2 Diabetes (MK-0941-011).
The multiple dose study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of MK-0941 in Japanese patients with Type 2 Diabetes.
- Trial name
- NCT00754130
- Testing
- MK-0941
- Volunteers
- 16 people
- Sponsor
- Merck Sharp & Dohme LLC
Insulin Dependent Diabetes, Non Insulin Dependent Diabetes
Evaluation and Comparison of Noninvasive Blood Glucose Concentrations
Comparison of noninvasive glucose measurement performance versus standard invasive reference measurements.
- Conditions
- Insulin Dependent Diabetes, Non Insulin Dependent Diabetes, Gestational Diabetes
- Trial name
- NCT01745900
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Chronic Hepatitis C, Insulin Resistance
NIDDM and IR in Combination Therapy for CHC
The influence of insulin sensitivity and glucose tolerance on the effects of antiviral therapy for HCV remains unclear. The aim of the present study was (1) To elucidate the clinical and virological factors associated with…
- Trial name
- NCT00687999
- Testing
- pegylated interferon alpha and ribavirin
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Diabetes Mellitus, Liver
Safety Study of Pioglitazone Compared To Glyburide on Liver Function
The purpose of this study is to determine the liver safety of pioglitazone, once daily (QD), versus glyburide taken with metformin and insulin.
- Trial name
- NCT00494312
- Testing
- Pioglitazone, Glyburide
- Volunteers
- 2,120 people
- Sponsor
- Takeda
Diabetes, Type 2 Diabetes (T2DM)
CGM Use in Non-insulin Patients With DM2
The U.S. Food and Drug Administration (FDA) has approved multiple Continuous Glucose Monitoring (CGM) devices from different manufacturers to be used as an aide in patients with type 1 and type 2 diabetes who require medications…
- Conditions
- Diabetes, Type 2 Diabetes (T2DM), Obesity Type 2 Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
- Trial name
- CGM-DWI (NCT07128342)
- Testing
- CGM Group, FSBG group
- Volunteers
- 100 people
- Sponsor
- Milwaukee VA Medical Center
Type 2 Diabetes
Evaluating the Effects of a Study Medication on Exercise Function in Type 2 Diabetes
People who are overweight or who have type 2 diabetes mellitus (T2DM) have higher levels of certain fats in their blood. The blood vessels and heart of most of these individuals do not work normally and people with T2DM also have…
- Trial name
- AcT2 (NCT01580813)
- Testing
- Acipimox
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Uveitis
Daclizumab Injections to Treat Non-Infectious Sight-Threatening Uveitis
This study will examine the safety and effectiveness of a monoclonal antibody called daclizumab in treating uveitis, an eye inflammation.
- Trial name
- NCT00043667
- Testing
- Daclizumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Eye Institute (NEI)
Diabetes Mellitus, Non-Insulin-Dependent
Zinc Supplementation in Type 2 Diabetics
Zinc supplementation reduces the extent of oxidative damage and improves vascular indices in type 2 diabetics
- Trial name
- NCT01309620
- Testing
- Zinc gluconate
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Healthy Subjects
The Acute Effect of Atorvastain on Renal Function in Patients With Type II Diabetes
We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium excretion, glomerular filtration rate, tubular function and vasoactive hormones in patients with type II diabetes, not in treatment with…
- Trial name
- NCT00678522
- Testing
- Atorvastatin
- Where
- 2 sites in Denmark
- Volunteers
- 25 people
- Sponsor
- Regional Hospital Holstebro
Cardiovascular Diseases, Heart Diseases
Central Obesity and Disease Risk in Japanese Americans
To conduct a longitudinal study of central obesity and related risk factors found to be associated with hypertension and atherosclerotic cardiovascular disease (ASCVD) in a previously-examined cross-sectional cohort of…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Hypertension
- Trial name
- NCT00005365
- Sponsor
- University of Washington
Diabetes Mellitus, Non-Insulin-Dependent
Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)
To compare the efficacy of three strategies of lifestyle changes associated with Januvia (sitagliptin) 100 mg/day in patients with Type 2 Diabetes Mellitus (T2DM) inadequately controlled by metformin (hemoglobin A1c [HbA1c]…
- Trial name
- NCT00545584
- Testing
- sitagliptin phosphate, Comparator: Diet, Comparator: Physical Activity
- Volunteers
- 1,512 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Efficacy and Safety of TAK-875 in Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to determine the safety and efficacy of multiple doses of TAK-875, once daily (QD), in subjects with Type 2 Diabetes Mellitus.
- Trial name
- NCT01007097
- Testing
- TAK-875, Glimepiride
- Where
- 71 sites in United States, Guatemala and 1 more
- Volunteers
- 426 people
- Sponsor
- Takeda
Type 2 Diabetes
Virtual World Health Behavior Counseling for Patients With Diabetes
Comparison of 2 methods of delivery health education for African-American women with Type 2 Diabetes. The two methods are: face to face education in small groups, as compared to delivering the same curriculum in the virtual…
- Trial name
- NCT01340079
- Testing
- virtual world, face to face
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Boston Medical Center
Type 2 Diabetes Mellitus, Non Insulin Dependent, Diabetes Mellitus, Non-Insulin-Dependent
A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)
A study to see if better control of type 2 diabetes can occur in patients taking a stable dose of metformin when they are also provided either sitagliptin or glimepiride.
- Trial name
- NCT00701090
- Testing
- sitagliptin, Comparator: glimepiride, open-label metformin
- Volunteers
- 1,035 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Non-Insulin-Dependent
An Evaluation of an Oral Antidiabetic Agent for the Treatment of Type 2 Diabetes
The purpose of this study is to determine if an investigational drug is safe and efficacious for poorly controlled type 2 diabetes mellitus.
- Trial name
- NCT00065312
- Testing
- naveglitazar
- Where
- 42 sites in United States
- Sponsor
- Eli Lilly and Company
Non Insulin Dependent Diabetes Mellitus
Prospective Observatonal Study for Effect of Duodenojejunal Bypass and Gastric Bypass on T2DM Patients
Surgical treatment for type 2 diabetes has been taken note especially in less obese or non obese patients. In Asian, the nuber of less obses or non obese patients with T2DM is greater than that of the obese.
- Trial name
- T2DM (NCT01735253)
- Testing
- laparoscopic roux en Y gastric bypass / open duodenojejunal bypass
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Inha University Hospital
Diabetes Mellitus, Non-Insulin-Dependent
MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)
The phase III clinical trial examines the efficacy, safety, and tolerability of the addition of MK0431/ONO-5435 to Japanese patients with type 2 diabetes mellitus (T2DM) who have inadequate glycemic control on diet/exercise…
- Trial name
- NCT00837577
- Testing
- Sitagliptin, Voglibose
- Volunteers
- 133 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
Comparison Of Morning And Evening Dosing Of Valsartan And Lisinopril In Patients With Diabetes
A study comparing the antihypertensives Valsartan and Lisinporil when doses are in the morning and comparing a morning dose of Valsartan with an evening dose.
- Trial name
- NCT00241124
- Testing
- valsartan, lisinopril
- Where
- Germany
- Volunteers
- 1,099 people, healthy volunteers welcome
- Sponsor
- Novartis
Diabetes Mellitus Non-insulin-dependent
An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)
To support the registration of sitagliptin 100mg in china.
- Trial name
- NCT00642798
- Testing
- sitagliptin phosphate
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC