Clinical trials: Non-Invasive Ventilation, open to volunteers
- Condition Non-Invasive Ventilation
- Status Open to volunteers
- Funder type Industry (pharma, biotech, devices)
COPD (Chronic Obstructive Pulmonary Disease), Obesity Hypoventilation Syndrome (OHS)
The Effect of Mask Design on Ventilation Parameters in COPD and OHS Patients on Long-term Home Non-invasive Ventilation. An Experimental Study.
Chronic obstructive pulmonary disease (COPD) and obesity hypoventilation syndrome (OHS) are respiratory conditions that disrupt normal breathing.
- Trial name
- NCT06972589
- Testing
- Investigational Mask, Conventional mask
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Patient Ventilator Interactions
Analysis and Evaluation of Asynchronies Between NIV Patients and Their Prisma VENT or LUISA Ventilator
This study aims to analyze the types, rates, and patterns of disturbances between the breathing of patients receiving non-invasive ventilation and their ventilator (patient-ventilator asynchronies, PVA) during routine therapy…
- Trial name
- NCT07768748
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Löwenstein Medical Technology GmbH & Co. KG
COPD (Chronic Obstructive Pulmonary Disease), Obesity Hypoventilation Syndrome (OHS)
Assessment of Breathing Pattern During NIV
COPD and OHS are respiratory conditions that disrupt normal breathing. Positive airway pressure, specifically Non-Invasive Ventilation (NIV), has been shown to improve breathing and reduce symptoms in patients with these…
- Trial name
- NCT06682286
- Testing
- NIV mask A, NIV mask B
- Where
- New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Respiratory Insufficiency Requiring Mechanical Ventilation
Registry for Automated Mechanical VEntilation in Adults
The aim of the here proposed study is to assess safety, performance and provide real world evidence (RWE) of the Hamilton Medical AG automated mechanical ventilation software packages in consecutive critically ill patients…
- Trial name
- RAVE (NCT06655805)
- Testing
- Non-invasive ventilation, Invasive mechanical ventilation, high-flow nasal oxygen
- Where
- 4 sites in Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Hamilton Medical AG
Respiratory Insufficiency, Respiratory Failure
Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask.
Study Overview The goal of this clinical trial is to learn whether an improved non invasive ventilation mask with airway washout can reduce how often people need to breathe and perform as well as standard NIV masks when used with…
- Trial name
- NCT07484802
- Testing
- NIV interface with airway washout
- Volunteers
- 60 people
- Sponsor
- Fisher and Paykel Healthcare
Focus of the Study is the Anatomy of the Soft Palate, Non-invasive Ventilation
The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway
The goal of this clinical trial is to understand the impact of the size and shape of the soft palate on gas airflow in the upper airway in healthy volunteers.
- Trial name
- NCT06738589
- Testing
- non-invasive ventilation
- Where
- New Zealand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Pulmonary Disease, Chronic Obstructive (COPD), Hypercapnia
Effectiveness and Efficiency of Home Telemonitoring and Non-invasive Ventilation in Patients With COPD and Hypercapnia (EVALECO)
The purpose of this study is to evaluate the effectiveness and clinical efficiency of combining home non-invasive ventilation (NIV) with a continuous remote telemonitoring (TM) system in patients with Chronic Obstructive…
- Trial name
- EVALECO (NCT07679646)
- Testing
- Home Non-Invasive Ventilation and Telemonitoring
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Air Liquide Healthcare Spain
Respiratory Failure Requiring Non Invasive Ventilation
NIV With Airway Washout for Dual Limb Ventilation: Improvement in Minute Ventilation
This is a prospective, non-randomized, non-blinded, crossover feasibility investigation to assess the safety, usability, and efficacy of the investigational mask in the hospital environment.
- Trial name
- NCT06939920
- Testing
- Non-invasive ventilation mask with airway washout, non-invasive ventilation
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnoea (OSA)
Feasibility of Upper Airway Stimulation in OSA
Project Breathe 1 is a short-duration (5 month) pilot investigation to assess the safety and tolerability of non-invasive electrical stimulation in adults with obstructive sleep apnoea.
- Trial name
- NCT07396649
- Testing
- Non-invasive electrical stimulation
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Notos Medical Limited
Healthy Volunteers
The Effect of Home and Hospital Mask Designs on Respiratory Variables in Healthy Volunteers
The goal of this randomized cross-over study is to investigate whether the design of non-invasive ventilation (NIV) mask impacts respiratory variables in healthy volunteers on NIV therapy.
- Trial name
- NCT07463716
- Testing
- Non-invasive ventilation (NIV)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare