Clinical trials: Non-Invasive Ventilation
Chronic Respiratory Failure With Hypercapnia
Impact of Humidification on Sleep Quality During Home Non Invasive Ventilation
Protocol Summary: 1. Question Does the adjunction of a humidification system to non-invasive ventilation circuit improve sleep quality and comfort of chronic ventilated respiratory insufficient patients? Does it change the…
- Trial name
- IMHUNIV (NCT03561974)
- Testing
- Humidification
- Where
- France
- Volunteers
- 30 people
- Sponsor
- ADIR Association
Pulmonary Disease, Chronic Obstructive
A Psychological Intervention to Promote Acceptance and Adherence to NIV in People With COPD
This study aims to analyze the impact of a brief psychological support intervention in the promotion of the adherence to Non Invasive Ventilation (NIV) among people with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02499653
- Testing
- Psychological Intervention, Videos
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Obstructive Pulmonary Disease
Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial
Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV).
- Trial name
- NCT04834037
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Respiratory Distress of Newborn
Comparison of Continuous Positive Airway Pressure and Non Invasive Positive Pressure Ventilation
The objective of the study is to compare the effectiveness of treatment with Non Invasive Positive Pressure Ventilation (NIPPV) and continuous positive airway pressure (CPAP) in decreasing the requirement for endotracheal…
- Trial name
- NCT03347136
- Testing
- CPAP, NIPPV
- Where
- Sri Lanka
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Sri Lanka
Acute Respiratory Distress Syndrome, Noninvasive Ventilation
Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome
The objective of this study is to evaluate the efficacy of noninvasive ventilation with helmet in reducing endotracheal intubation rates in comparison with Noninvasive Ventilation (NIV) facemask among patients with Acute…
- Conditions
- Acute Respiratory Distress Syndrome, Noninvasive Ventilation, Corona Virus Disease, Acute Respiratory Failure
- Trial name
- NCT04507802
- Testing
- Non invasive ventilation via helmet
- Where
- Qatar
- Volunteers
- 60 people
- Sponsor
- Hamad Medical Corporation
Neonates, Respiratory Distress
Non-invasive Secondary Respiratory Support in Late Preterm and Term Infants
The aim of the present work is to compare between various modes of non-invasive respiratory support (including NCPAP, NIPPV, and NHFOV) as secondary respiratory support modes in late preterm and term neonates as regards the need…
- Conditions
- Neonates, Respiratory Distress, Non- Invasive Ventilation
- Trial name
- NCT07000071
- Testing
- NCPAP, NIPPV, NHFOV
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Respiratory Insufficiency
BIPAP Vision Versus OPTIFLOW System Comparison in Acute Respiratory Failure After Cardio Thoracic Surgery
The OPTIFLOW ™ use is becoming more common in acute respiratory failure cases, but its place in relation to VNI (Bi-PAP mode) is not yet defined.
- Trial name
- OPTIFLOW (NCT01458444)
- Testing
- Non invasive ventilation (VNI), Non invasive ventilation
- Where
- France
- Volunteers
- 830 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Acute Respiratory Failure
High Flow Nasal Cannulas in Children
Non-invasive Continuous Positive Airway Pressure (nCPAP) is widely recognized as an efficient respiratory support in infants with mild to moderate Acute Hypoxemic Respiratory Failure (AHRF).
- Trial name
- HFNC (NCT03689686)
- Testing
- Noninvasive Respiratory Support
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
COVID-19
Respiratory Supports and COVID-19 Mortality
Critically ill COVID-19 patients have a relatively high mortality rate (~30%). Most critically ill COVID-19 patients require respiratory supports.
- Trial name
- NCT04832061
- Testing
- Respiratory supports
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Yale University
Noninvasive Ventilation
Low Versus High PEEP in Noninvasive Ventilation for Hypoxemic Respiratory Failure
Current study aimed to explore the effect of high PEEP during noninvasive ventilation among hypoxemic patients with acute respiratory failure.
- Trial name
- NCT05193786
- Testing
- Different level of PEEP
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Chongqing Medical University
Respiratory Distress Syndrome, Newborn
RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress Syndrome
Noninvasive ventilation defines methods of providing ventilation support with constant or variable pressure using nasal or nasopharyngeal interfaces without endotracheal intubation or tracheostomy.
- Trial name
- NCT03366714
- Testing
- nasal CPAP support with RAM cannula, nasal CPAP support with Hudson cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Chronic Obstructive Pulmonary Disease
The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world, being the fourth leading cause of death in the world.
- Trial name
- NCT02680639
- Testing
- BiPAP Synchrony ventilator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Philips Respironics
COPD Exacerbation Acute, COPD Exacerbation
PSV Versus ASV With Intellisync Mode for Delivery of NIV in AECOPD
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined acute worsening of respiratory symptoms requiring additional therapy.
- Trial name
- PAINT-COPD (NCT06160687)
- Testing
- PSV mode during NIV, ASV intellisync
- Where
- India
- Volunteers
- 55 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hypoxemia
The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)
The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of…
- Trial name
- NCT02713737
- Testing
- heated humidified high-flow nasal cannula, noninvasive ventilation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Lung Cancer (Non-Small Cell), Lung Metastases From Any Primary
Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function
This clinical study is evaluating different treatment options for patients with malignant lung tumors, including both primary lung cancer and tumors that have spread to the lungs from other parts of the body.
- Trial name
- NCT07272356
- Testing
- Surgery, Ablation, SBRT
- Where
- Lithuania
- Volunteers
- 68 people
- Sponsor
- Aurimas Macionis
Pulmonary Edema, Respiratory Insufficiency
Mortality and Risk Factors in Patients With Acute Cardiogenic Pulmonary Edema: a Multicentric, Observational, Prospective Study
The purpose of this study is to define the current treatment of patients ospitalized with acute cardiogenic pulmonary edema. Clinical and laboratory data collected in the Emergency Department will used to investigate the primary…
- Trial name
- ACPE (NCT01269177)
- Testing
- Non invasive ventilation
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Milan
Chronic Obstructive Pulmonary Disease
Non-invasive Mechanical Ventilation as a Rescue Therapy to Relieve Dyspnea in Patients With Stable Severe COPD
The purpose of this study is to determine whether non-invasive mechanical ventilation(NIV), playing the role as a rescue therapy , are effective in relieving exertional dyspnea in stable severe COPD patients.
- Trial name
- NCT02012101
- Testing
- niv plus oxygen therapy, oxygen therapy
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Position on Premature Infants, Nursing Care
The Effect of Positioning on Comfort, Stress Levels, and Physiological Functions in Premature Infants
A randomized crossover study was made to investigate the effect of different positions on the comfort, stress, and physiological functions of premature infants receiving non-invasive mechanical ventilation in the neonatal…
- Trial name
- NCT06752005
- Testing
- Intervention Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Aydin Adnan Menderes University
Hypoxia
Evaluation of RDS MultiSense® in Desaturation Analysis in Healthy Volunteers
In this clinical study, the investigators will compare vital parameters measurements obtained using continuous data from reference monitors and continuous wireless MultiSense® monitoring patch in 30 healthy volunteers under…
- Trial name
- HYPO (NCT05044585)
- Testing
- Remote Automated Monitoring System
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- IHU Strasbourg
Preterm Infants
LISA vs INSURE in the Treatment of Respiratory Distress Syndrome in Preterm Infants
To evaluate the efficacy of less invasive surfactant administration（LISA ）technique in the treatment of neonatal respiratory distress syndrome（NRDS） by comparing with the traditional Intubate-Surfactant-Extubate（INSURE） technique.
- Trial name
- NCT04126382
- Testing
- Intubate-Surfactant-Extubate(INSURE), less invasive surfactant administration(LISA)
- Volunteers
- 200 people
- Sponsor
- Anhui Provincial Hospital