Clinical trials: Non-Nutritive Sweetener, open to volunteers
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
Postprandial Glucose, Glucose Levels
Ultra-processed Food-reducing Intervention and Continuous Glucose Monitoring
The goal of this trial is to investigate whether reduction in ultra-processed food intake through dietary counseling and education can improve postprandial glucose responses and glycemic variability compared with a usual diet in…
- Conditions
- Postprandial Glucose, Glucose Levels, Hyperglycemias
- Trial name
- ULTRA-CGM (NCT07175701)
- Testing
- 40-minute one-on-one dietary counseling and nutrition education aimed at reducing ultra-processed food consumption, Standard dietary counseling and nutrition education based on national guidelines
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Korea University
Neuropsychology, Ingestive Behavior
Parsing the Impact of Calories Versus Sweet Taste on Beverage Brand Conditioning
The purpose of this study is to learn how the sweet taste and the calorie content of a beverage affect the way people respond to the brand logo printed on that beverage.
- Trial name
- PSK (NCT07883096)
- Testing
- 3-week daily beverage intervention
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Type 2 Diabetes Mellitus (T2DM)
Short-Term Effects of Sucralose and Saccharin on Blood Sugar and Gut Microbiota in Type 2 Diabetes
This clinical trial investigates the short-term effects of two commonly used non-nutritive sweeteners (NNS), saccharin and sucralose, on blood glucose regulation and the gut microbiota in adults with Type 2 Diabetes Mellitus…
- Trial name
- NCT07124585
- Testing
- Sucralose, Saccharin
- Where
- Malaysia
- Volunteers
- 33 people
- Sponsor
- National University of Malaysia
Prediabetes
Glycemic Impact of NNS Via the Gut Microbiome
This pilot study will evaluate the feasibility and acceptability of a 30-day sucralose intervention among adults with prediabetes.
- Trial name
- NCT07868432
- Testing
- Sucralose
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tufts University
Non-Nutritive Sweetener, Type 1 Diabetes
Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful…
- Conditions
- Non-Nutritive Sweetener, Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT07434544
- Testing
- Cherry Sports Drink
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Inflamatory Bowel Disease, Crohn Disease (CD)
Non-nutritive Sweeteners in Inflammatory Bowel Disease
This study will focus on the commonly used non-nutritive sweetener (NNS) sucralose (2 sachets/day resulting in daily dose: sucralose 2.5mg/kg) and its role in changing the gut microbiota in humans with IBD, compared to healthy…
- Trial name
- NCT07769437
- Testing
- Sucralose (non-nutritive sweetener)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Healthy Volunteers - Male and Female
Resting-state Imaging and Chronic Consumption of Non-Nutritive SweetenerS
Non-nutritive sweeteners are used as a substitute for simple sugars to improve the palatability of food products without increasing their sugar and calorie content.
- Trial name
- RNSS (NCT07183254)
- Testing
- administration of questionnaires, carrying out a MRI scan, Can distribution visit for subjects in the "non/low" sweetener consumption group
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand