Clinical trials: Non-Pharmacological Interventions
Alzheimer Disease
Memesto Wearable Device for Persons With Dementia
An estimated 70% of the 7.2+ million people in the U.S. with Alzheimer's Disease and Alzheimer's Disease-Related Dementias experience agitation, characterized by poorly organized and purposeless psychomotor activity that…
- Trial name
- NCT05153161
- Testing
- Memesto
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Edgewater Safety Systems, Inc.
Mild Cognitive Impairment (MCI)
Exercises for Rehabilitation of COgnition and Lifestyle Enhancement in Patients With Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) is a clinical condition with a heterogeneous etiology and clinical course characterized by objective cognitive deficits not severe enough to cause clear functional limitations or to warrant a…
- Trial name
- ERCOLE (NCT07517380)
- Testing
- Multimodal Group Cognitive Rehabilitation Intervention, Active Control
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Casa di Cura IGEA
Migraine, Headache Disorders
High-Intensity Interval Training and Progressive Muscle Relaxation as a Movement-Based Group Intervention for the Non-Pharmacological Prevention of Adolescent Migraine
Background: The prevalence of migraine during adolescence is 7.7%, affecting 9.7% of girls and 6.0% of boys. Despite its high prevalence, treatment options remain limited.
- Conditions
- Migraine, Headache Disorders, Pediatric Migraine
- Trial name
- MigraFit (NCT07850622)
- Testing
- Weekly group training
- Where
- Austria
- Volunteers
- 27 people
- Sponsor
- Medical University Innsbruck
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Exercise, Renal Dialysis
Exercise Effect on Psychological Distress of Patients Undergoing Hemodialysis at Al-Suwaiq Dialysis Center
The aim to investigate the level of psychological distress on patients undergoing hemodialysis at Al-Suwaiq Renal dialysis center as well as to explore the effectiveness of home-based exercise method in reducing such…
- Conditions
- Exercise, Renal Dialysis, Anxiety, Depression
- Trial name
- NCT07083843
- Testing
- Exercise, Standard medical treatment
- Where
- Oman
- Volunteers
- 54 people
- Sponsor
- Oman Ministry of Health
Healthy Aging
Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Executive control processes involve initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT05506852
- Testing
- Web-based training strategy, Web-based regular training (no strategy)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Influenza
A Randomised Controlled Trial of Face Masks and Hand Hygiene in Reducing Influenza Transmission in Households
This study will test the effectiveness of face masks and hand cleaning in preventing the spread of influenza within households
- Trial name
- NCT00425893
- Testing
- hand hygiene, health education, face masks
- Where
- China
- Volunteers
- 6,069 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cognitive Dysfunction, Physical Inactivity
Effects of Intradialytic Cognitive and Physical Exercise Training on Functional Status of Hemodialysis Patients
The aim of this study is to investigate the effect of cognitive training combined with physical exercise on cognitive function, physical performance and frailty indicators in the hemodialysis population.
- Conditions
- Cognitive Dysfunction, Physical Inactivity, Chronic Kidney Diseases
- Trial name
- DIAKOG (NCT05150444)
- Testing
- Cognitive and physical exercise training
- Where
- Slovenia
- Volunteers
- 44 people
- Sponsor
- University Medical Centre Ljubljana
Mood Disorders, Major Depressive Disorder
Immune Activation, Neural Plasticity and Depression
Major depressive disorder (MDD) is a chronic, recurring and potentially life-threatening illness that affects up to 10% of the population across the globe.Increasing evidence indicates a clear link between immune dysfunction and…
- Conditions
- Mood Disorders, Major Depressive Disorder, Sleep Deprivation
- Trial name
- NCT06306248
- Testing
- Total sleep deprivation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS San Raffaele
Cancer-related Cognitive Impairment, Cancer-related Cognitive Dysfunction
CanCOG®: Pilot Trial of Cognitive Rehabilitation for Cancer Survivors
Cancer-related cognitive impairment (CRCI) affects a large proportion of non-central nervous system cancer survivors and can negatively impact cognitive functioning and daily life.
- Conditions
- Cancer-related Cognitive Impairment, Cancer-related Cognitive Dysfunction, Cancer-related Cognitive Difficulties, Depression and Anxiety Symptoms
- Trial name
- CanCOG® (NCT07755839)
- Testing
- CanCOG® - Cogntive Rehabilitation in Cancer
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Aveiro University
Chronic Pain, Mental Health Disorder
Therapeutic Writing for Adults Suffering From Chronic Pain and Comorbid Mental Health Disorders
The goal of this observational study is to understand the effects and experiences of therapeutic writing interventions in adult women with chronic pain and co-occurring mental health conditions.
- Conditions
- Chronic Pain, Mental Health Disorder, Psychiatric &Amp;Amp;or Mood Disorder, Psychiatric Comorbidities
- Trial name
- TWfCP&MH (NCT07058532)
- Testing
- Therapeutic Writing Intervention in Pain Rehabilitation
- Where
- Finland
- Sponsor
- Toni Salikka
Primary Dysmenorrhea (PD)
Graded Motor Imagery for Primary Dysmenorrhea
The goal of this clinical trial is to learn if graded motor imagery can reduce pain sensitivity and period pain in women with primary dysmenorrhea (painful periods with no medical cause).
- Trial name
- NCT07618832
- Testing
- Graded Motor Imagery (GMI)
- Where
- Pakistan
- Volunteers
- 81 people
- Sponsor
- Dr. Mehak Naeem
Acute Coronary Syndromes (ACS), Sleep Quality
Eye-Ear Sleep Band for Sleep Quality in Coronary Care Unit
Sleep disturbances are common in patients admitted to the coronary care unit (CCU), where continuous light, noise, and monitoring equipment disrupt normal sleep.
- Conditions
- Acute Coronary Syndromes (ACS), Sleep Quality, Sleep Deprivation
- Trial name
- EESQ-CCU (NCT07490743)
- Testing
- Eye-Ear Sleep Band, Standard CCU Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Koç University
Bowel Preparation for Colonoscopy
Individualized Non-pharmacological Intervention for Bowel Preparation
Colonoscopy is essential for the early detection of colorectal cancer. However, inadequate bowel preparation remains a common challenge, associated with reduced adenoma detection rates, prolonged procedure time, and increased…
- Trial name
- NCT07684716
- Testing
- Individualized bowel preparation regimen, Information-framing guidance, Standard bowel preparation guidance
- Where
- China
- Volunteers
- 339 people
- Sponsor
- General Hospital of Shenyang Military Region
Tobacco Cessation
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
The purpose of this study is to determine whether public housing residents trained in Tobacco Cessation and Motivational Interviewing Techniques to become Tobacco Treatment Advocates(TTA) will be effective in increasing the quit…
- Trial name
- NCT01651611
- Testing
- Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Boston University
Labor Pain, Anxiety
Breathing Exercises During Labor and Maternal Outcomes
This randomized controlled trial evaluated the effects of guided breathing exercises applied during labor on maternal stress, pain, anxiety, birth satisfaction, and labor outcomes.
- Conditions
- Labor Pain, Anxiety, Stress, Psychological
- Trial name
- NCT07566026
- Testing
- Guided Breathing Exercises During Labor
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Nilgun Avci
Auditory Hallucinations, Schizophrenia Spectrum
Cost-utility Study of Cognitive-behavioral Management of Auditory Hallucinations in Schizophrenic Disorder
The aim of the study is to assess the effectiveness and costs of a cognitive-behavioral treatment (CBT) for auditory hallucinations (psychotherapy) as an adjunct to usual care, comparing it to the effectiveness and costs of usual…
- Trial name
- VOICES (NCT07134816)
- Testing
- Cognitive and behavioral therapy for auditory hallucinations, Usual treatment
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Montpellier
Intensive Care Unit Delirium
Prevention of Delirium in ICU Using Multimodal Interventions
This study was designed to evaluate the impact of non-pharmacological multimodal interventions including ongoing orientation, sensory correction, setting of familiar circumstance and promotion of sleep enviromnet for prevention…
- Trial name
- NCT05950958
- Testing
- Multimodal therapy for prevention of delirium
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Seoul National University Hospital
Confort, Older Adults With Cancer
Enhancing Patient Experience in Geriatric Oncology
Approximately 60% of new cancer diagnoses and 70% of cancer-related deaths occur in adults aged 65 years and older, a population frequently affected by multimorbidity, frailty, sensory impairment, and treatment-related symptom…
- Trial name
- NCT07671586
- Testing
- Comfort menu and cart implemented
- Where
- Brazil
- Volunteers
- 264 people
- Sponsor
- Hospital Sirio-Libanes
Stress, Non Pharmacological Intervention
Effects of Swaddling and Nesting on Pain and Stress in Newborns
This study aims to investigate the effects of swaddling and cradling methods on pain and stress levels in newborn infants receiving respiratory support.
- Conditions
- Stress, Non Pharmacological Intervention, Newborn Diseases
- Trial name
- NCT07335263
- Testing
- swaddling, Nesting
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kutahya Health Sciences University