Clinical trials: Non-allergic Rhinitis
Common Cold, Acute Respiratory Infection
Efficacy and Safety of XC8, Film-coated Tablets, 40 mg in Patients With Dry Non-productive Cough Against Acute Respiratory Viral Infection
Study to assess the efficacy and safety of XC8, film-coated tablets, 10 mg in comparison with placebo in patients with dry non-productive cough against acute respiratory infection.
- Conditions
- Common Cold, Acute Respiratory Infection, Influenza, Human
- Trial name
- NCT05273619
- Testing
- XC8, film-coated tablets, 10 mg
- Where
- 6 sites in Russia
- Volunteers
- 250 people
- Sponsor
- Valenta Pharm JSC
Common Cold
Safety and Efficacy Study of Oral XIGO Tablets to Treat The Common Cold
The purpose of the study will be to assess the efficacy and safety of XIGO administered orally, three times a day, compared with placebo in patients with the common cold.
- Trial name
- NCT01092039
- Testing
- lactoferrin, L-Glutamine and beta-glucans
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Xigo Health LLC
Common Cold/Flu, Nasal Congestion
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults
Phase III clinical trial to evaluate the efficacy and safety of a fixed-dose combination of 1000 mg dipyrone monohydrate + 60 mg caffeine + 4 mg chlorpheniramine maleate in improving symptoms of the common cold and flu in adults.
- Conditions
- Common Cold/Flu, Nasal Congestion, Nasal Obstruction
- Trial name
- PANAMA (NCT07626437)
- Testing
- dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg
- Where
- 15 sites in Brazil
- Volunteers
- 620 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Common Cold
A Study of Nasal Glucagon in Participants With a Common Cold
The main purpose of this study is to evaluate the safety of nasal glucagon (NG) in participants with a common cold, some of whom will also take a nasal decongestant.
- Trial name
- NCT02778100
- Testing
- Nasal Glucagon, Oxymetazoline
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Nasal Congestion
A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
The study will evaluate the safety and efficacy of the study medical device plus standard of care versus standard of care in subjects between 3 and 48 months (inclusive) presenting symptoms of a common cold.
- Trial name
- NCT05365789
- Testing
- Blocked Nose Baby nasal spray, Standard of care
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Common Cold, Pharyngitis
Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold
The purpose of this study is to determine the efficacy and safety of 1000 mg Aspirin (study medication) by comparing 1000 mg Paracetamol (study medication) in treating the symptoms of sore throat associated with a common cold.
- Conditions
- Common Cold, Pharyngitis, Tonsillitis
- Trial name
- NCT01465009
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 8 sites in United Kingdom
- Volunteers
- 508 people
- Sponsor
- Bayer
Acute Nasopharyngitis
A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults
2-DG-02 is a randomized, placebo-controlled, double-blind Phase 2 study to investigate the efficacy and safety of 2-Deoxy-D-Glucose as a pre-exposure prophylaxis using the rhinovirus challenge model in healthy study participants.
- Trial name
- NCT06375772
- Testing
- 2-Deoxy-D-glucose
- Where
- Netherlands
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- G.ST Antivirals GmbH
Common Cold
Study to Evaluate the Efficacy of EZC Pak in Adults With Upper Respiratory Infection (URI)
A randomized-controlled interventional clinical trial to evaluate the effectiveness of EZC Pak \& EZC Pak+D for the treatment of the common cold and/or a URI.
- Trial name
- NCT04943575
- Testing
- EZC Pak, EZC Pak +D
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- PPC Pharmaceuticals
Respiratory Tract Diseases
Study of Echinaforce Junior Tablets in Children With Acute Colds
This study aims to investigate safety and efficacy of Echinaforce Junior tablets in two dosages of 3 x 1 and 5 x 1 tablets per day in children 4 - 12 years old with acute colds.
- Trial name
- NCT02198391
- Where
- Switzerland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Common Cold
Echinaforce Junior Bioavailability Trial
In this bioavailability trial should be shown that the one of the main active constituent in alcoholic echinacea extracts, the alkylamide dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamide (short: tetraen) is bioavailable in…
- Trial name
- NCT03070314
- Testing
- Echinaforce junior
- Where
- Switzerland
- Sponsor
- A. Vogel AG
Allergic Rhinitis Due to Grass Pollens
International Registry on the Quality of Life of Patients With Grass-pollen-induced Allergic Rhinitis
The purpose of the present study is to describe patient's perception of quality of life and effectiveness of ORALAIR® over a follow-up period up to 5 years, in real-life settings.
- Trial name
- ALTO (NCT02041624)
- Where
- France
- Volunteers
- 740 people
- Sponsor
- Stallergenes Greer
Common Cold, Nasal Mucosal Inflammation
Post Market Clinical Follow-Up Study - Medical Device KalobaNaso
The goal of this observational PMCF study is to confirm the efficacy and safety of the medical device KalobaNaso (a nasal spray) in children, adolescents and adults with common cold symptoms, such as runny nose, nasal congestion…
- Conditions
- Common Cold, Nasal Mucosal Inflammation, Rhinitis
- Trial name
- PMCF (NCT05960318)
- Testing
- KalobaNaso spray, KalobaNaso junior spray
- Where
- Italy
- Volunteers
- 131 people
- Sponsor
- Schwabe Pharma Italia
Healthy
A Study Investigating the Safety and Efficacy of Bio-Active Silver Hydrosol™ in Providing Immune Support
The objective of this study is to investigate the ability of Bio-Active Silver Hydrosol™ in providing immune support in healthy adult males and females participating in intense aerobic exercise.
- Trial name
- NCT04144673
- Testing
- Silver Hydrosol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Natural Immunogenics Corp.
Common Cold
Study Comparing 3 Formulations to Evaluate the Efficacy and Safety of the Inflammatory Symptoms of the Upper Respiratory Tract, in Children Between 2 and 6 Years Old
The primary outcome of this study is to evaluate the clinical efficacy of the dose fixed combination and each drug, that composes it, isolated, regarding the respiratory symptoms improvement in superior air passages acute…
- Trial name
- NCT00967759
- Testing
- Bronpheniramine and fenilefrine (Decongex Plus), Bronpheniramine isolated, Fenilefrine isolated
- Where
- Brazil
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Common Cold
Mucinex Exploratory Cold Study
This is an exploratory, multicenter, randomized, blinded, placebo-controlled study of Mucinex in patients with colds. Patients will receive 7 days of treatment with either Mucinex or placebo.
- Trial name
- NCT01046136
- Testing
- guaifenesin (Mucinex)
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Reckitt Benckiser Inc.
Common Cold
Iota-Carrageenan Nasal Spray in Common Cold
The aim of this clinical trial is to investigate the effect of Iota-Carrageenan treatment on cold symptoms. The effect of treatment on the duration of the cold and the patients viral load plus cytokine level indicating the…
- Trial name
- NCT01944631
- Testing
- Iota-Carrageenan
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Boehringer Ingelheim
Influenza, Human, Acute Respiratory Infection
Study of Post-Exposure Ingavirin® Prophylaxis of Influenza and Acute Respiratory Viral Infections
The purpose of the study was to evaluate efficacy of prophylactic Ingavirin intake by people having contact with sick people infected with influenza and other acute respiratory viral infections
- Conditions
- Influenza, Human, Acute Respiratory Infection, Common Cold, Flu
- Trial name
- NCT03189537
- Testing
- Ingavirin (Imidazolyl Ethanamide Pentandioic Acid)
- Where
- 2 sites in Russia
- Volunteers
- 400 people
- Sponsor
- Valenta Pharm JSC
Rhinitis, Allergic, Perennial
A Pilot Study In Adults And Adolescents With Irritant (Non-Allergic) Rhinitis
The purpose of this pilot study is to compare the effects (effectiveness and safety)of an intranasal corticosteroid (fluticasone furoate nasal spray [FFNS]) with a placebo nasal spray for the treatment of irritant (non-allergic)…
- Trial name
- NCT00730756
- Testing
- Fluticasone Furoate Nasal Spray
- Where
- 5 sites in Thailand
- Volunteers
- 102 people
- Sponsor
- GlaxoSmithKline
Common Cold, Upper Respiratory Tract Infection (URTI)
Effect of Immune X on Common Cold Incidence in Healthy Adults
The goal of this clinical trial is to learn if Immune X can help prevent common cold events in healthy adults who have a history of upper respiratory tract infections.
- Trial name
- CELFI (NCT07787130)
- Testing
- Immune X
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Upper Respiratory Disease, Influenza
Immune Defense Protein Impact On Respiratory Immune Outcomes
The primary goal of this study is to observe the impact of the IDP® Supplement on the duration and severity of upper respiratory symptoms in older individuals during the cold and flu season.
- Conditions
- Upper Respiratory Disease, Influenza, Viral Upper Respiratory Infection
- Trial name
- NCT07431840
- Testing
- Immune Defense Protein 50mg Dose, IDP 200mg Dose
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Quantec Ltd