Clinical trials: Non-cardiac Thoracic Surgery
Operative, Non Cardiac, Thoracic Disease
Comparison of Intra and Extraluminal Bronchial Blocker in Adults
The objective of this study is to evaluate the time and ease of placement of an extra-luminal Arndt bronchial blocker versus placing it intra-luminally.
- Trial name
- NCT02646813
- Testing
- Intraluminal Placement, Extraluminal Placement
- Volunteers
- 42 people
- Sponsor
- Wake Forest University Health Sciences
Cardiopathy, Surgery
Bilevel Positive Airway Pressure in Cardiac Surgery
The purpose of this study was to determine the effects of Bilevel Positive Airway Pressure (BiPAP) on variables clinics, cardiorespiratory and physical functional in patients undergoing cardiac surgery at the University Hospital…
- Trial name
- NCT02600182
- Testing
- Bilevel Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Prof. Dr. Antônio Marcos Vargas da Silva
Stable Angina Pectoris, Periodontitis
Effect of Periodontal Therapy on Asprosin in Stable Angina
This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis.
- Trial name
- NCT07591844
- Testing
- Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Coronary (Artery); Disease
Follow-up of Patients With Multivessel Coronary Artery Disease After CABG
The FAMOUS Trial is a single-center, prospective, randomized study aimed to compare three different strategies (clinical, anatomical, or functional) in preventing MACE after CABG.
- Trial name
- FAMOUS (NCT03040700)
- Testing
- Myocardial Perfusion Scan, Coronary CTA
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Ministry of Health, Brazil
Hemostasis, Hemostatic Techniques
A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery
The objective of this clinical investigation is to evaluate the safety and efficacy of ETHIZIA to control minimal, mild, or moderate soft tissue bleeding during open surgery when compared to SURGICEL Original in the percentage of…
- Trial name
- NCT06664788
- Testing
- ETHIZIA, SURGICEL Original
- Where
- 7 sites in United States, Netherlands
- Volunteers
- 108 people
- Sponsor
- Ethicon, Inc.
Controlling Mild to Moderate Bleeding During Surgery
The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study
The objective of this study is to evaluate the safety and hemostatic effectiveness of EVARREST as an adjunct to controlling mild to moderate soft hepatic parenchyma or soft tissue bleeding during open hepatic, abdominal, pelvic…
- Trial name
- NCT03255174
- Testing
- EVARREST® Fibrin Sealant Patch
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery
Assisted Fluid Management IDE Study
The primary objective of this study is to evaluate the performance of the Acumen™ Assisted Fluid Management (AFM) Feature in its ability to predict a subject's fluid responsiveness.
- Conditions
- Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery, Pelvic Surgery, Major Peripheral Vascular Surgery
- Trial name
- AFM (NCT03469570)
- Testing
- EV1000 Clinical Platform with Assisted Fluid Management (AFM) Feature
- Where
- 10 sites in United States
- Volunteers
- 330 people
- Sponsor
- Edwards Lifesciences
Hemorrhage, Soft Tissue Bleeding
EVARREST™ Fibrin Sealant Patch Post-Market Study
The objective of this study is to evaluate the clinical utility of EVARREST™ Fibrin Sealant Patch (Fibrin Pad) as an adjunct to hemostasis in soft tissue bleeding during intra-abdominal (stomach area), retroperitoneal (hip and…
- Trial name
- EVARREST (NCT01902459)
- Testing
- EVARREST™ Fibrin Sealant Patch, Standard of Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ethicon, Inc.
Postoperative Atrial Fibrillation
The Effect of Intra Operative Dexmedetomidine in Prevention of Early Postoperative Atrial Fibrillation
The incidence of atrial fibrillation (AF) after lung resection varies between 12% and 30% after lobectomy and 23%-67% after pneumonectomy. The average time of onset of AF after lung resection is 2-3 days.
- Trial name
- NCT05320705
- Testing
- Intra Operative Dexmedetomidine
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain, Acute Post-Operative, Anxiety
Effects of Reflexology and Cold Application Before Chest Tube Removal in CABG Patients
This randomized controlled trial evaluated the effects of foot reflexology and cold application, administered separately before chest tube removal, on pain, state anxiety, and physiological parameters in patients following…
- Conditions
- Pain, Acute Post-Operative, Anxiety, Chest Tube Removal, Coronary Artery Bypass
- Trial name
- NCT07528482
- Testing
- Reflexology, Cryotherapy alone
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Hemorrhage, Soft Tissue Bleeding
The Paediatric EVICEL® Soft Tissue and Parenchymal Organ Bleeding Study
To evaluate the safety and effectiveness of EVICEL® Fibrin Sealant (Human) as an adjunct to achieve haemostasis during surgery in paediatric patients.
- Trial name
- NCT02227706
- Testing
- EVICEL® Fibrin Sealant, SURGICEL® Absorbable Hemostat
- Where
- 13 sites in Belgium, Canada and 1 more
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.
Chest Pain, Acute Coronary Syndrome
HEART Pathway Implementation
The purpose of this study is to determine the effectiveness of the HEART Pathway, a clinical decision aid for the care of patients with chest pain, in a "real-world" clinical setting.
- Conditions
- Chest Pain, Acute Coronary Syndrome, Chest Pain Atypical Syndrome, Chest Pain Rule Out Myocardial Infarction
- Trial name
- NCT02056964
- Where
- United States
- Volunteers
- 14,717 people
- Sponsor
- Wake Forest University Health Sciences
Lung Cancer
Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function
RATIONALE: Video-assisted surgery followed by radiation therapy may be an effective treatment in patients whose poor heart and lung function make them high risk for standard surgery.
- Trial name
- NCT00002624
- Testing
- adjuvant therapy, diagnostic thoracoscopy, therapeutic thoracoscopy
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 66 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Myocardial Injury, Thoracic Diseases
Effects of Ciprofol on Myocardial Injury After Non-cardiac Surgery in Video-Assisted Thoracoscopic Surgery
Myocardial injury after noncardiac surgery (MINS) refers to postoperative elevation of cardiac troponin (cTn) levels caused by underlying ischemic mechanisms (i.e., coronary artery supply-demand imbalance or atherosclerotic…
- Conditions
- Myocardial Injury, Thoracic Diseases, Thoracoscopic Surgery
- Trial name
- CP-MINS (NCT07028593)
- Testing
- Propofol, ciprofol
- Where
- China
- Volunteers
- 1,058 people
- Sponsor
- Tongji Hospital
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
Pulmonary Complications in Surgical Patients
Effect of Delayed Remote Ischemic Preconditioning on Postoperative Pulmonary Complications in Elderly Patients Having Non-Cardiac Thoracic Surgery
Study Summary: The Effect of a Simple Arm Cuff Procedure on Lung Complications After Surgery in Older Adults 1. What is the purpose of this study? This clinical study aims to find out if a simple, non-invasive procedure called…
- Trial name
- NCT07208500
- Testing
- RIPC
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Shanghai Geriatric Medical Center
Thoracic, Surgery
Non Invasive Cardiac Output Evaluation With Starling SV for Lung Elective Surgery
Intraoperative hemodynamic optimization decreases postoperative complications and length of stay in high risk patient. Therefore, continuous monitoring of cardiac output (Qc) is recommended to guide fluid management.
- Trial name
- NICOLE (NCT04251637)
- Testing
- Cardiac output monitoring with Starling SV.
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Ischemic Heart Disease, Lung Injury
Effect of Human Umbilical Cord-derived Mesenchymal Stem Cells on Non-cardiac Surgery-induced Lung Injury
This study is an exploratory clinical study to observe the improvement of lung function before and after the treatment by human umbilical cord-derived mesenchymal stem cells, and the purpose is to evaluate the safety and…
- Conditions
- Ischemic Heart Disease, Lung Injury, Non-cardiac Surgery
- Trial name
- NCT04996966
- Testing
- human umbilical cord-derived mesenchymal stem cells, saline
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Shanghai East Hospital
Thoracic Surgery
Evaluation of the Alveolar Recruitment Obtained During Non-invasive Ventilation After Cardiac Surgery
The great majority of cardiac surgery patients develop a degree of post-operatory respiratory failure. This is due to several factors.
- Trial name
- ARCTICS (NCT02804997)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens