Clinical trials: Non-invasive
Bronchiolitis
Intrapulmonary Percussive Ventilation for Children With Bronchiolitis on Non-Invasive Ventilation Support
Prospective randomized study of patients admitted to the Pediatric Intensive Care Unit suffering from Bronchiolitis and are supported on Non Invasive Positive Pressure Ventilation.
- Trial name
- NCT03037801
- Testing
- Intrapulmonary Percussive Ventilation (Percussionaire Corp, Sandpoint, Idaho)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Intrabony Defect, Periodontal Diseases
RGD With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defect
Periodontal regeneration is a complex process that involves coordinated activities and interactions of many cell types, extracellular matrix, cytokines, and specific growth factors to restore tissue integrity.
- Conditions
- Intrabony Defect, Periodontal Diseases, Alveolar Bone Loss
- Trial name
- MINST + RGD (NCT06936605)
- Testing
- RGD Peptide
- Volunteers
- 45 people
- Sponsor
- Minia University
Non-Muscle-Invasive Bladder Cancer
AFU Registry of the Therapeutic Management and Follow-up of Non-Muscle-Invasive Bladder Cancer
The AFU has set itself the task of setting up a register of medical practices in order to define possible improvements in the therapeutic management and follow-up of NMIBC.
- Trial name
- TVNIM-AFU (NCT05002556)
- Where
- 44 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Association Francaise d'Urologie
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pregnant Women, Rh-Hr Blood-Group System
Fetal RhD Genotye Non Invasive Prenatal Determination
Actually, our center is doing the prenatal determination of RhD fetal genotype in all RhD negative pregnant women. The investigator want to demonstrate that this is an useful and efficient method.
- Trial name
- NCT02788383
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
ALS (Amyotrophic Lateral Sclerosis)
Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease
Motor neuron disease (MND) is a progressive neurological disorder involving degeneration of motor neurons, leading to muscle weakness, speech and swallowing difficulties, and respiratory failure.
- Trial name
- NCT07067229
- Testing
- Personalized rTMS, Standard rTMS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Visceral Obesity, Atherosclerosis
Abdominal Fat and Imaging Measurements of Heart Disease
Although it is frequently mentioned in the media that overweight and obesity have reached epidemic proportions worldwide and in this country, some Canadians are perplexed and sometimes confused about the role of obesity in…
- Conditions
- Visceral Obesity, Atherosclerosis, Metabolic Syndrome
- Trial name
- NCT01447745
- Where
- Canada
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Laval University
Respiration Disorders
Multicenter Prospective Observational Study on Diaphragmatic Function Assessment by Ultrasound in Patients With Acute Respiratory Failure Receiving Non-invasive Mechanical Ventilation or High Flow Nasal Canula
The primary goal of this study is to assess diaphragm function in patients with acute respiratory failure before and during the use of high-flow oxygen and/or non-invasive breathing support.
- Trial name
- DIAFUSION (NCT06892912)
- Testing
- Diaphragmatic ultrasound
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Foro Internacional en Cuidado Crítico
Hepatocellular Carcinoma, Portal Hypertension
CT-based HVPG Assessment for Predicting the Prognosis of HCC With TACE (CHANCE-CHESS 2302)
This study aims to evaluate the impact of non-invasive CT-based Hepatic Venous Pressure Gradient (HVPG) assessment on prognosis of hepatocellular carcinoma (HCC) patients treated with transarterial chemoembolization (TACE).
- Trial name
- NCT05704192
- Testing
- TACE ± Systemic therapy
- Where
- 2 sites in China
- Volunteers
- 373 people
- Sponsor
- Zhongda Hospital
Pregnancy, Monitoring
Feasibility Study: Continuous Fetal Monitoring During Maternal Exercise
This feasibility study will be the first study to assess the feasibility of continuous electrophysiological monitoring during maternal exercise in women with an uncomplicated pregnancy.
- Trial name
- NIEM-S (NCT07077109)
- Testing
- Electrophysiological monitoring
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Scoliosis
Study of the Surgical Treatment of Early Onset Scoliosis Using a Non-invasive Growing Rod
It is current practice for children who have surgery for early onset scoliosis (EOS) to be treated with insertion of extendable implants known as growth rod systems.
- Trial name
- NCT01362881
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- Ellipse Technologies, Inc.
Adult, Acute Respiratory Failure Admitted in ICU
Early Non Invasive Ventilation in Immuno-compromized Patients With Acute Respiratory Failure.
Assess the superiority of early non invasive ventilation in comparison to Oxygen therapy only, for immuno-compromized patients with acute respiratory failure
- Conditions
- Adult, Acute Respiratory Failure Admitted in ICU, Immuno Compromized
- Trial name
- IVNICTUS (NCT01915719)
- Testing
- Early non invasive ventilation, Oxygen therapy only
- Where
- France
- Volunteers
- 374 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Skin Lesions
Non-invasive Melanoma Assessment Using a Topical Fluorescence Reagent and Optical Imaging
The use of MDS to access the presence of melanoma in the skin.
- Trial name
- NCT02056522
- Where
- 2 sites in Israel
- Volunteers
- 357 people
- Sponsor
- Orlucent, Inc
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults
This study evaluates the use of the EarFlo device in adults with clinically confirmed Eustachian tube dysfunction and/or otitis media with effusion.
- Conditions
- Otitis Media With Effusion (OME), Eustachian Tube Dysfunction, Otitis Media With Effusion
- Trial name
- NCT07777302
- Testing
- EarFlo Device
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Philip Perez
Dehydration, Hypovolemia
Validation of a Wearable Bioimpedance Sensor for Hydration Monitoring
The purpose of the project is to validate the performance of a wearable bioimpedance sensor (Re:Balans®) for monitoring hydration status.
- Trial name
- VAMOS (NCT07655401)
- Testing
- Bioimpedance sensor
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Mode Sensors AS
Chronic Thyroid Disease
T1 Tissue Mapping as a Non Invasive Biomarker for Quantification of Chronic Thyroid Related Microscopic Myocardial Fibrosis.
CMR T1 tissue mapping helps in detection and quantification of the microscopic myocardial fibrosis and is more accurate and non invasive maneuver.
- Trial name
- NCT07247981
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chest Pain, CAD
Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD
Rationale: Patients with chest pain usually undergo multiple diagnostic examinations to demonstrate or rule out atherosclerotic coronary artery disease (CAD).
- Trial name
- CLEAR-CAD (NCT05344612)
- Testing
- CT Coronary Angiography
- Where
- Netherlands
- Volunteers
- 6,444 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Periodontal Disease, Periodontitis
Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique
This randomized controlled clinical trial aims to evaluate the effectiveness of using nano-hyaluronic acid (nano-HyA) gel alongside a minimally invasive non-surgical technique (MINST) to treat deep intrabony defects in patients…
- Trial name
- NCT07595757
- Testing
- Minimally invasive non-surgical technique (MINST), nano-hyaluronic acid
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Neuromuscular Diseases
MSOT as Non-invasive Biomarker for Diagnosis and Monitoring of Neuromuscular Diseases
The goal of this study is to learn if Multispectral Optoacoustic Tomographs (MSOT) works to diagnose and follow the course of neuromuscular diseases (NMDs) in children.
- Trial name
- NCT06438965
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Children's Hospital of Eastern Ontario
Type I Complex Regional Pain Syndrome
Non Invasive Neurostimulation Technology for the Treatment of Type I Complex Regional Pain Syndrome (CRPS I)
Complex Regional Pain Syndrome (CRPS) / Complex Regional Pain Syndrome (CRPS) is a chronic neurological disorder that affects the extremities and is characterized by disabling pain, swelling, vasomotor instability, sudomotor…
- Trial name
- NCT05052736
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Las Palmas de Gran Canaria
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