Clinical trials: Non-invasive
Superficial Bladder Cancer
Phase 2b, Trial of Intravesical DTA-H19/PEI in Patients With Intermediate-Risk Superficial Bladder Cancer
This study is designed to assess the efficacy and safety of DTA-H19/PEI given as six intravesical instillations of 20 mg of plasmid DNA complexed with PEI into the bladder of patients with intermediate risk superficial bladder…
- Trial name
- NCT00595088
- Testing
- BC-819/PEI
- Where
- 6 sites in United States, Israel
- Volunteers
- 47 people
- Sponsor
- Anchiano Therapeutics Israel Ltd.
Unwanted Flanks Fat
UltraShape Device Using the U-Sculpt/VDF Transducer for Flanks Fat
Prospective, blinded, one arm, baseline-controlled clinical study for the evaluation of the UltraShape treatment for non-invasive fat and circumference reduction.
- Trial name
- NCT02465762
- Testing
- ultrashape Fat reduction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Breast Cancer Invasive Nos, Stage 0 Breast Carcinoma
Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers
The purpose of this study is to determine whether a new surgical technique (radioguided seed localization) for localizing nonpalpable breast tumours is better than the standard technique (needle localization).
- Trial name
- NCT00225927
- Testing
- radioguided seed localization for nonpalpable breast cancers
- Where
- 3 sites in Canada
- Volunteers
- 333 people
- Sponsor
- McMaster University
Neurologic Disorder, Paralysis
EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis
Neuralis is an innovative assistive technology designed for individuals with severe neuromuscular conditions, enabling wheelchair control through EEG signals.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT06169696
- Testing
- Intervention/Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Synaptrix Labs Inc.
Cardiac Arrhythmia
StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias
This is a prospective, single-center, phase II trial that will be monitoring the safety and efficacy of using stereotactic ablative radiotherapy (SBRT) to treat patients with a medical condition affecting heart rate and rhythm…
- Trial name
- START-CA (NCT04843683)
- Testing
- Stereotactic Ablative Radiotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Motor Adaptation and Generalization, Posterior Parietal Cortex
Examining Lateralized Aspects of Motor Control Using Non-invasive Neural Stimulation
Motor adaptation and generalization are believed to occur via the integration of various forms of sensory feedback for a congruent representation of the body's position in space along with estimation of inertial properties of the…
- Conditions
- Motor Adaptation and Generalization, Posterior Parietal Cortex, Cerebellum
- Trial name
- NCT05947279
- Testing
- Comparing motor adaptation reaching performance
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Endothelial Dysfunction
Evaluation of a New Non-Invasive Device for Detection of Endothelial Dysfunction
The purpose of the study is to investigate the sensitivity and specificity of the Endotect compared with an ultrasound device in a flow-mediated vasodilatation (FMD) test.
- Trial name
- NCT00650741
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lavi Cardiatec
Cardiac Disease
Comparison of NICOM and Innocor for Non-Invasive Determination of Cardiac Output
Cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The aim of the study at hand was to evaluate NICOM (bioreactance) as a new method for determinion of CO and to compare it to Innocor…
- Trial name
- NCT02331342
- Testing
- NICOM cardiac output measurement, Innocor cardiac output measurement
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Trisomy 21
Study of High Risk Non Invasive Prenatal Test Population
The investigator want to study the population of high risk (over 1/50) of Trisomy 21. According to french guidelines, these patients needs to have a invasive test (such as amniocentesis) but some patients prefer to have a Non…
- Trial name
- NCT04737070
- Testing
- Prenatal test for Trisomy 21 screening
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Diabetic Nephropathies MeSH:D003928, Diabetes Mellitus, Type 2
Wearable NH₃ Sensor for Remote Non-invasive Monitoring and Diagnosis of Diabetic Kidney Disease
This observational study aims to validate whether a novel wearable sensor can non-invasively and remotely assess the renal health status of patients with diabetes by detecting the concentration of ammonia (NH₃) in exhaled breath…
- Conditions
- Diabetic Nephropathies MeSH:D003928, Diabetes Mellitus, Type 2, Kidney Diseases
- Trial name
- NCT07875010
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Shanghai Pudong Hospital
COPD Exacerbation, COPD Exacerbation Acute
Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this clinical trial is to test if treatment with prehospital Non-invasive ventilation (NIV) for patients with acute respiratory failure (ARF), due to acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- COPD Exacerbation, COPD Exacerbation Acute, Noninvasive Ventilation, Emergency Medical Services
- Trial name
- PRENIV (NCT06211920)
- Testing
- Non-invasive ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Central Denmark Region
Acute Respiratory Failure
Epidemiology of Respiratory Insufficiency in Critical Care
Acute respiratory failure is a common entity in intensive care units nowadays and is associated with significant morbidity and mortality, thus representing a major health problem.
- Trial name
- ERICC (NCT01268410)
- Where
- Brazil
- Volunteers
- 773 people
- Sponsor
- Hospital Sirio-Libanes
Blood Pressure, Blood Pressure Measurement
NIBP Accuracy Study for Adult
The purpose of this study is developing new NIBP enhancement.
- Trial name
- NCT07684859
- Where
- Finland
- Sponsor
- GE Healthcare
Intracerebral Hemorrhage, Cerebral Hemorrhage
MIECH: The Minimally Invasive Endoscopic Surgery With the Axonpen System for Spontaneous Intracerebral Hemorrhage
The primary objective of this trial is to provide preliminary safety data of minimally invasive endoscopic surgery using the Axonpen™ system for spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Intracerebral Hemorrhage, Cerebral Hemorrhage, Intracranial Hemorrhage, Basal Ganglia Hemorrhage
- Trial name
- NCT04839770
- Testing
- Axonpen system
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Clearmind Biomedical Inc.
Systemic Hypertension
Non-Invasive Blood Pressure Measurement in Critically Ill PAtients Post Cardiosurgical Therapy
The aim of the present study is to evaluate the accuracy of measuring beat-by-beat diastolic blood pressure from a non-invasive, cuffless and non-obtrusive watch-like optical device worn at the wrist.
- Trial name
- IMPACT (NCT03710473)
- Testing
- Optical sensor, Pulse watch
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Muscle Invasive Bladder Carcinoma
FL- 101 Study in Non-Metastatic MIBC
A pilot window of opportunity study of FL-101 in patients with non-metastatic MIBC who are eligible for radical cystectomy (RC) but are ineligible for, or decline, cisplatin-based neoadjuvant therapy.
- Trial name
- NCT05395260
- Testing
- FL-101
- Sponsor
- Flame Biosciences
Cardiac Resynchronization Therapy
Comparison of Multi-point Pacing and Conventional CRT Through Non-invasive Hemodynamics Measurement and Global Longitudinal Strain Assessment
Pilot, perspective, multi-center non-randomized study comparing Multi-point pacing and conventional CRT through non-invasive hemodynamics measurement and Global Longitudinal Strain assessment
- Trial name
- COMPACT-MPP (NCT04299360)
- Testing
- Cardiac Resynchronization Therapy device programming
- Where
- 3 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Azienda Ospedaliera Universitaria Mater Domini, Catanzaro
Healthy
Medicsen Smartpatch: Safety & Performance (SOUNDD)
The goal of this clinical trial is to understand the efficacy of Medicsen's Smartpatch to deliver drugs through the skin in healthy volunteers.
- Trial name
- SOUNDD (NCT07615959)
- Testing
- Medicsen Smartpatch, Subcutaneous (SC) single dose
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medicsensors S.L
Bladder Cancer, Metastatic Bladder Cancer
A Window of Opportunity Trial: Avelumab in Non-metastatic Muscle Invasive Bladder Cancer
This is a pilot study of avelumab in patients with non-metastatic, muscle invasive bladder cancer who are eligible for radical cystectomy (RC), but are ineligible for cisplatin based neoadjuvant therapy.
- Conditions
- Bladder Cancer, Metastatic Bladder Cancer, Invasive Bladder Cancer
- Trial name
- NCT03498196
- Testing
- Avelumab
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Baylor College of Medicine
Diabetes Mellitus
Technological-based Personalized Care Intervention for Supporting Older People With Diabetes Mellitus
The objectives of this project are (1) to develop a new model of DM management using non-invasive healthcare technology for continuous glucose monitoring; (2) to use health apps to give timely personalized care intervention for…
- Trial name
- NCT06783907
- Testing
- Non-invasive blood glucose monitoring, Traditional blood glucose monitoring
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Metropolitan University
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