Clinical trials: Non-invasive
Non-Muscle Invasive Bladder Cancer, NMIBC
Sample Collection for Ongoing Research and Product Evaluation Study - Non-muscle Invasive Bladder Cancer (SCORE-NMIBC)
The SCORE-NMIBC study is a prospective, multi-center, study designed to collect data and biological samples from participants diagnosed with non-muscle Invasive Bladder Cancer (NMIBC).
- Conditions
- Non-Muscle Invasive Bladder Cancer, NMIBC, High-risk Non-Muscle Invasive Bladder Cancer
- Trial name
- SCORE-NMIBC (NCT07763197)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Natera, Inc.
Leukoderma
Evaluation of Treatment for Leukoderma by Cellular Level Resolution Full-field Optical Coherence Tomography
OCT is an optical technology that emerged as a non-invasive skin imaging for the skin. In this protocol, the investigators plan to study the optical imaging features of leukoderma.
- Trial name
- NCT04935424
- Testing
- ApolloVue® S100 Image System (Apollo Medical Optics)
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Chang Gung Memorial Hospital
Surgery
Peripheral Regional Blockade and EMG
The investigators are studying a type of technology that is already used called surface electromyography (EMG). This measures and records electrical activity using sensor stickers in a non-invasive way.
- Trial name
- Electromyogram (NCT06982027)
- Testing
- BlockSynop surface electromyography device, Peripheral nerve block
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nationwide Children's Hospital
Healthy
Non-invasive Measurement of Glucose with Advanced Spectroscopy Techniques and Machine Learning Models
Primary aim of this pilot study is to provide evidence for a non-invasive, continuous, and transcutaneous measurement method to determine blood glucose levels robustly and accurately.
- Trial name
- NCT06406075
- Testing
- Lab demo 1.0
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liom Health AG
ADHD
Non-invasive Brain Stimulation for Pediatric ADHD
The possibility of influencing brain activity and steadily enhancing behavioral performance through external intervention has long fascinated neuroscientists.
- Trial name
- NCT03104972
- Testing
- tDCS, tRNS
- Where
- Israel
- Volunteers
- 47 people
- Sponsor
- Hebrew University of Jerusalem
Surgery--Complications
Goal-directed Therapy in Neurosurgery.
The purpose of the study is to assess feasibility of future large randomised controled study aimed on assessment of effect of goal-directed therapy on incidence of complications in neurosurgery compared to standard care.
- Trial name
- NCT04754295
- Testing
- Goal-Directed Therapy, STANDARD
- Where
- Czechia
- Volunteers
- 34 people
- Sponsor
- Brno University Hospital
Low-grade NMIBC, FGFR Gene Amplification
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC
- Conditions
- Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations, FGFR3 Gene Alteration
- Trial name
- SURF302 (NCT06995677)
- Testing
- TYRA-300 60mg, TYRA-300 50mg, TYRA-300 Dose 70 mg
- Where
- 48 sites in United States, Australia and 2 more
- Volunteers
- 90 people
- Sponsor
- Tyra Biosciences, Inc
Persistent Post-concussive Symptoms
Transcutaneous Auricular Vagus Nerve Stimulation for Persistent Post-concussion Symptoms
Persistent post-concussive symptoms (PPCS) affect a significant proportion of individuals following a concussion, leading to debilitating impacts on their quality of life and work capacity.
- Trial name
- taVNS-PPCS (NCT07017257)
- Testing
- Active taVNS
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- University of Liege
Non-muscle Invasive Bladder Cancer
Urine-based Molecular Testing vs Cystoscopy for Surveillance of Nonmuscle Invasive Bladder Cancer (NMIBC)
The purpose of this study is to evaluate patient-reported preference for urine based molecular testing (CxBladder Monitor) compared to cystoscopy for patients on surveillance for Nonmuscle Invasive Bladder Cancer (NMIBC).
- Trial name
- NCT06126796
- Testing
- CxBladder Monitor, Cystoscopy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Mayo Clinic
Preoxygenation, Anaesthesia Induction
An Algorithmic Approach to Preoxygenation
The aim of this randomized controlled trial is to evaluate an algorithmic approach to gradually adding pressure-supported ventilation and end-tidal positive pressure when conventional tidal volume breathing is insufficient for…
- Conditions
- Preoxygenation, Anaesthesia Induction, Non-invasive Positive Pressure Ventilation
- Trial name
- NCT06736197
- Testing
- Group TVB, Group PSV, Group PSV+PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 378 people
- Sponsor
- Pamukkale University
General Anaesthesia
Accuracy of CNAP PPV Under General Anaesthesia
Noninvasive pulse pressure variation for the guidance of perioperative fluid therapy is compared with the gold standard of invasive measurements. Cardiac output is derived by the PICCO monitor.
- Trial name
- NCT02166580
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University Hospital Schleswig-Holstein
Blood Pressure, Arterial Stiffness
Comparison of Different Non-invasive Methods to Assess Pulse Wave Analysis
The primary goal of the study is to compare different methods for pulse wave measurement and analysis which are cuffless and contactless. The novel measurement tools will be compared to cuff-based reference methods.
- Conditions
- Blood Pressure, Arterial Stiffness, Arrythmia
- Trial name
- MULTI-PWA (NCT05790642)
- Testing
- Pulse wave measurement and analysis
- Where
- Germany
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Acquired Brain Injury, Recovery of Function
Does Physiotherapy Plus Non-invasive Brain Stimulation Improve Motor Recovery in Children With Acquired Brain Injury?
The current study will evaluate the feasibility of transcranial direct current stimulation (tDCS) combined with an existing intensive physiotherapy program for children with ABI within the in/day-patient brain injury program at…
- Conditions
- Acquired Brain Injury, Recovery of Function, Transcranial Electrical Stimulation
- Trial name
- NCT04422886
- Testing
- active transcranial direct current stimulation (tDCS), Physiotherapy
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Depression - Major Depressive Disorder
Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains
Spinal interoceptive pathways (SIPs) convey bodily signals to an interoceptive system in the brain and their dysregulation is linked to major depressive disorder (MDD).
- Trial name
- MOSPID (NCT06795451)
- Testing
- transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Cincinnati
Alzheimer Disease
Memory Functions in Mild Alzheimer's Disease
The overall objective of this project is to examine the effects of non-invasive brain stimulation on episodic memory performance
- Trial name
- MemStim-lab (NCT04785053)
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Cardiac Output, Blood Pressure
Cardiac Function as Measured by Non-invasive Electrical Velocimetry Cardiac Monitor in Hospitalized Children
To assess whether a non-invasive cardiac output monitor can follow heart function in children during treatments in the hospital. To establish a normal reference for children who are well and awake.
- Trial name
- NCT01030445
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Boston Children's Hospital
Acute Coronary Syndrome, Percutaneous Transluminal Coronary Angioplasty
Establish a Telecare Model of Acute Coronary Syndrome Patient With Heart Stent Implantation by a Non-invasive Wearable Device and Artificial Intelligence Cloud to Reducing Medical Adverse Events.
Heart disease is still one of the world's most important health problems, and it ranks second among the top ten causes of death among Taiwan.
- Trial name
- NCT04455568
- Testing
- use EKG Wisdom bracelet
- Volunteers
- 400 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Elective Surgical Procedures
Evaluation of Non-Invasive Assessment for Post RFAL Procedure Monitoring Using the Nanowear Wearable Multiple Sensor Vest
The objective of this study is to evaluate an experience of post-operative monitoring using the Nanowear wearable multiple sensor vest in plastic surgery
- Trial name
- NCT04721405
- Testing
- Observational Study: No intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Nanowear Inc.
Blood Pressure Monitoring
Measurement Agreement Between IBP and NIBP During Induction of Anesthesia in High Risk Patients
The AGREE-BP study aims to evaluate how closely blood pressure measurements taken with an automated upper-arm cuff agree with measurements taken through a small plastic tube placed in an artery, called an arterial catheter…
- Trial name
- AGREE-BP (NCT07870356)
- Testing
- non-invasive oscillometric blood pressure monitoring
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Graz
Dyspnea, Acute Decompensated Heart Failure
Evaluation of Cardiopulmonary Diseases by Ultrasound
Historically, ultrasound imaging of the lung parenchyma has been challenging because of the high total ultrasound energy attenuation and scattering by the air in the lungs.
- Trial name
- NCT02248831
- Testing
- Recording Doppler ultrasound signals noninvasively
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Echosense Ltd.
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