Clinical trials: Noninvasive
Oral Dissolution Therapy, Extracorporeal Shock Wave Lithotripsy
The Efficacy of Oral Dissolution Therapy (ODT), Extracorporeal Shock Wave Lithotripsy (ESWL), and Combined ESWL and ODT as Non-Invasive Modalities for Treating Small and Medium-Sized Radiolucent Renal Stones
This study aimed to compare oral dissolution therapy (ODT), extracorporeal shock wave lithotripsy (ESWL), and a combination of ESWL and ODT as noninvasive modalities for treating small and medium-sized renal radiolucent.
- Conditions
- Oral Dissolution Therapy, Extracorporeal Shock Wave Lithotripsy, Noninvasive, Small
- Trial name
- NCT06814834
- Testing
- Oral dissolution therapy, Extracorporeal shock wave lithotripsy, Oral dissolution therapy + extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease
Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial
Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV).
- Trial name
- NCT04834037
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Esophagus Cancer
Clinical Study on Noninvasive Evaluation of Ivonescimab Antibody Distribution and Expression in Esophageal Cancer Patients by 89Zr-AK112 PET Imaging
As a humanized bispecific antibody targeting PD-1 and VEGF-A, everolizumab exhibits high specificity for binding PD-1 and VEGF-A in vivo.
- Trial name
- NCT07440212
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Respiratory Distress Syndrome, Noninvasive Ventilation
Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome
The objective of this study is to evaluate the efficacy of noninvasive ventilation with helmet in reducing endotracheal intubation rates in comparison with Noninvasive Ventilation (NIV) facemask among patients with Acute…
- Conditions
- Acute Respiratory Distress Syndrome, Noninvasive Ventilation, Corona Virus Disease, Acute Respiratory Failure
- Trial name
- NCT04507802
- Testing
- Non invasive ventilation via helmet
- Where
- Qatar
- Volunteers
- 60 people
- Sponsor
- Hamad Medical Corporation
Acute Respiratory Failure
High Flow Nasal Cannulas in Children
Non-invasive Continuous Positive Airway Pressure (nCPAP) is widely recognized as an efficient respiratory support in infants with mild to moderate Acute Hypoxemic Respiratory Failure (AHRF).
- Trial name
- HFNC (NCT03689686)
- Testing
- Noninvasive Respiratory Support
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lumbar Stabilization Surgery, Noninvasive Hemoglobin Monitoring
Effect of Prone Position on Continuous Noninvasive Hemoglobin Measurement
This prospective observational study aims to evaluate whether the prone position affects the agreement between noninvasive hemoglobin (SpHb) measurements and laboratory hemoglobin values in patients undergoing lumbar…
- Trial name
- NCT07823569
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Glioblastoma, Glioblastoma Multiforme
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma
This clinical study to evaluate sonobiopsy is significant because sonobiopsy will fundamentally enhance the clinician's insight into the molecular features of an intracranial lesion to tailor treatment approaches and optimize…
- Trial name
- NCT05281731
- Testing
- Sonobiopsy, Research blood, Cancer Personalized Profiling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Noninvasive Ventilation
Low Versus High PEEP in Noninvasive Ventilation for Hypoxemic Respiratory Failure
Current study aimed to explore the effect of high PEEP during noninvasive ventilation among hypoxemic patients with acute respiratory failure.
- Trial name
- NCT05193786
- Testing
- Different level of PEEP
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Chongqing Medical University
Parkinson Disease
Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
This is a pilot randomized, sham-controlled, double-blind, multi-center study evaluating the safety and preliminary effectiveness of the Gen0Bh Transcranial Focused Ultrasound System for the treatment of motor symptoms in…
- Trial name
- NCT07207122
- Testing
- Gen0Bh Transcranial Focused Ultrasound System (Active)
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sanmai Technologies PBC dba Sanmai
Retinal Vascular Disease
Swept-Source Optical Coherence Tomography for Noninvasive Retinal Vascular Imaging
This is a clinical pilot study to assess the feasibility of using a swept-source optical coherence tomography (SSOCT) system to perform noninvasive imaging of the retinal vasculature in patients with existing microvascular…
- Trial name
- SWEPT (NCT01834196)
- Testing
- Swept-Source Optical Coherence Tomography
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Cardiac Physiology, Cardiac Output
The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation
The purpose of this study is to test the accuracy of a new noninvasive way to measure how much blood our heart pumps per minute.
- Trial name
- NCT00783679
- Testing
- NICO device
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Septic Shock
Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output Monitoring
This randomized controlled study investigates the value of critical care ultrasound and non-invasive cardiac output monitoring in guiding fluid resuscitation for patients with septic shock in the emergency department.
- Trial name
- CUS-NICOM-SS (NCT07162857)
- Testing
- non-invasive cardiac output monitoring, Ultrasonic technology
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Mai Xiaowei
COPD, Hypercapnic Respiratory Failure
Efficacy of High-intensity NPPV and Low-intensity NPPV in Patients With Chronic Hypercapnic COPD
High-intensity noninvasive positive pressure ventilation (NPPV), which can well improve the gas exchange and reduce the work of breathing of patients, is a new strategy targeted at maximally reducing arterial carbon dioxide.
- Trial name
- NPPV;COPD (NCT03238014)
- Testing
- Noninvasive positive pressure ventilation
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Respiratory Distress Syndrome, Newborn
RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress Syndrome
Noninvasive ventilation defines methods of providing ventilation support with constant or variable pressure using nasal or nasopharyngeal interfaces without endotracheal intubation or tracheostomy.
- Trial name
- NCT03366714
- Testing
- nasal CPAP support with RAM cannula, nasal CPAP support with Hudson cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Chronic Obstructive Pulmonary Disease
The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world, being the fourth leading cause of death in the world.
- Trial name
- NCT02680639
- Testing
- BiPAP Synchrony ventilator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Philips Respironics
Depression - Major Depressive Disorder
Effect of Neurofeedback and TMS
The goal of this clinical trial is to is to learn whether adding EEG neurofeedback (NFB) to repetitive transcranial magnetic stimulation (rTMS) is safe and feasible for adults with major depressive disorder (MDD).
- Trial name
- NCT07892287
- Testing
- Repetitive Transcranial Magnetic Stimulation, Alpha-down EEG Neurofeedback
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
ARDS (Acute Respiratory Distress Syndrome)
EIT Evaluation of the Impact of Inhaled Nitric Oxide on Ventilation/Perfusion Mismatch in ARDS Patients Receiving Noninvasive Respiratory Support
This study aimed to quantitatively evaluate the immediate effect of inhaled nitric oxide on the ventilation / perfusion ratio in ARDS patients receiving nasal high flow oxygen therapy or noninvasive ventilation using electrical…
- Trial name
- NCT07617298
- Testing
- Inhale different doses of nitric oxide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ming Zhong
Ventricular Tachycardia
Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia
Prospective single-arm study investigating the safety of non-invasive cardiac radiosurgery for the treatment of ventricular tachycardia (VT).
- Trial name
- SMART-VT (NCT04642963)
- Testing
- Cardiac Radiosurgery
- Where
- 2 sites in Poland
- Volunteers
- 11 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Hypoxemia
The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)
The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of…
- Trial name
- NCT02713737
- Testing
- heated humidified high-flow nasal cannula, noninvasive ventilation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology