Clinical trials: Nonsuicidal Self-injury
Adolescents
Adolescents' Non-suicidal Behavior and Perception of Parents' Negative Emotional Expression and Family Communication
The starting point of this project is to study young people and adolescents, aiming to explore the correlation between non-suicidal behavior of young people and adolescents and the negative emotional expression of their parents…
- Trial name
- NCT06290115
- Testing
- Questionnaires set 1, Questionnaires set 2, Questionnaires set 3
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Borderline Personality Disorder
DBT for Chronically Self-harming Individuals With BPD: Evaluating the Clinical & Cost Effectiveness of a 6 mo. Treatment
Standard one-year dialectical behaviour therapy (DBT), which has four components, is an effective treatment for people with borderline personality disorder.
- Trial name
- FASTER-DBT (NCT02387736)
- Testing
- Dialectical Behaviour Therapy-6 months, Dialectical Behaviour Therapy-12 months
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- Centre for Addiction and Mental Health
Nonsuicidal Self-Injury
Internet-delivered Emotion Regulation Individual Therapy for Adolescents With NSSI - An Open Pilot Study
The primary aim is to investigate the effectiveness of an Internet-delivered Emotion Regulation Individual Therapy for Adolescents (ERITA) with nonsuicidal self-injury (NSSI).
- Trial name
- NCT02697019
- Testing
- Internet-delivered Emotion Regulation Individual Therapy for Adolescents
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Self-Injurious Behavior
Zero Self-Harm - a Mobile Phone Application to Reduce Non-suicidal Self-injury
Non-suicidal self-injury (NSSI), the deliberate, self-inflicted destruction of body tissue without suicidal intent and for purposes not socially sanctioned, is an increasing health care problem in Denmark.
- Trial name
- NCT04463654
- Testing
- Zero Self-Harm app
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Borderline Personality Disorder, Non-suicidal Self-injury (NSSI)
ERGT for Women Engaging in NSSI - an Effectiveness Study
The primary aim is to investigate the effectiveness of Emotion Regulation Group Therapy (ERGT) for women who self-harm in ordinary psychiatric outpatient health care.
- Trial name
- NCT01986257
- Testing
- Emotion Regulation Group Therapy (ERGT).
- Where
- Sweden
- Volunteers
- 97 people
- Sponsor
- Karolinska Institutet
NSSI
The Muti-centered Investigation，Pathogenesis and Intervention Study of Non-suicidal Self-injury Behavior in China
Non-suicidal self-injury (NSSINSSINSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT04094623
- Testing
- Dialectical behavior therapy, Social support group therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing Medical University
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Non-Suicidal Self Injury
A Case-Series Examination of a Brief CAT-Informed Intervention (CATCH-Y) for Young People That Have Self-Injured
Non-suicidal self-injury (NSSI), the term used for when somebody purposefully hurts themselves without intending to end their life. Often, it suggests that there are other difficulties going on in someone's life.
- Trial name
- CATCHY (NCT04708262)
- Testing
- Cognitive Analytic Therapy for Containing Self-Harm in Young People
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester
Nonsuicidal Self-injury, Depression
Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury
This is a feasibility trial of a digital mental health intervention aimed at adolescents (ages 14-18) with nonsuicidal self-injury and who are not currently engaged in mental health treatment.
- Conditions
- Nonsuicidal Self-injury, Depression, Anxiety
- Trial name
- NCT07224165
- Testing
- App-based digital mental health intervention for adolescent NSSI, App-based delivery of healthy living psychoeducational materials
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Non-suicidal Self-injury (NSSI), Adolescent
Neurobiological Markers of Non-suicidal Self-injury and Treatment Mechanisms of Adolescent Self-injury Intervention Skills Training
The goal of this clinical trial is to evaluate the effectiveness and safety of Adolescent Self-Injury Intervention Skills Training (ASIST), a treatment program developed by the research team, compared with treatment as usual…
- Trial name
- ASIST (NCT07910110)
- Testing
- Adolescent Self-Injury Intervention Skills Training (ASIST), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Borderline Personality Disorder (BPD)
Repetitive Transcranial Magnetic Stimulation Versus Theta Burst Stimulation on Impulsivity, Emotional Dysregulation, and Non-Suicidal Self-Injury in Borderline Personality Disorder Patients
the goal of this randomized clinical trial is to evaluate the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) and intermittent theta-burst stimulation (iTBS) in patients with borderline personality…
- Trial name
- TMS and TBS (NCT07919587)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Intermittent Theta-Burst Stimulation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Nonsuicidal Self Injury, Stigmatization
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and…
- Conditions
- Nonsuicidal Self Injury, Stigmatization, Cicatrix, Skin Transplantations
- Trial name
- NCT04420442
- Testing
- Scar Transformation Group
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Self-Harm, Deliberate, Non-Suicidal Self Injury
Aspects of Self-harm - Cognition, Imaging and Treatability
Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. This study aim at increased understanding of parameters associated with DSH with the long term goal to potentially improve and possibly personalise its…
- Conditions
- Self-Harm, Deliberate, Non-Suicidal Self Injury, Attempt Suicide, Personality Disorders
- Trial name
- NCT04905797
- Testing
- Emotional Stop Signal Task, Magnetic Resonance Imaging, World Health Organizations Disability Assessment Schedule (WHODAS 2.0)
- Where
- Sweden
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Region Skane
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol in Chinese Adolescents With Non-Suicidal Self-Injury
This study utilizes the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) to address non-suicidal self-injury among Chinese adolescents.
- Trial name
- NCT06858540
- Testing
- Unified protocol for transdiagnostic treatment of emotional disorders in adolescents
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Jian-Jun Ou