Clinical trials: Normal Aging
Early Onset Alzheimer Disease, Mild Cognitive Impairment
Reference Database & Longitudinal Registry of the Normal and Pathological Aging Brain
Establishment of a BNA reference database for the Adult and Elderly Population. Hypothesis-generating study designed to collect data that will aid in future scientific and engineering exploration of correlations between clinical…
- Conditions
- Early Onset Alzheimer Disease, Mild Cognitive Impairment, Depression, Aging
- Trial name
- (BNA™) (NCT02875496)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Skin Aging, Dry Skin
Human In Use Test of GINPI-HP-004 in Healthy Adults
The main objective of this study was to confirm skin acceptability of the product GINPI REF. GINPI BATCH: 10/06/2024 applied under normal use conditions in healthy female adult volunteers, under gynecological control, by means of…
- Trial name
- NCT07533474
- Testing
- Depigmentig cosmetic product
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- i+Med S.Coop.
Skin Aging
Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging
Facial skin aging is a complex process combining factors such as sun exposure, smoking and those that are believed to be inherited.
- Trial name
- NCT00974480
- Testing
- Redermic, Tretinoin (Rejuva-A)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Hyperpigmentation, Skin Ageing
Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen
A12-week single-center, open-label, clinical study is being conducted to assess the efficacy and tolerability of the Brightening Treatment paired with a skincare regimen on healthy female subjects aged 20-65 years with…
- Conditions
- Hyperpigmentation, Skin Ageing, Post Inflammatory Hyperpigmentation, Skin Roughness
- Trial name
- NCT07501000
- Testing
- Brightening Treatment
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Physiological Stress, Disorder of Aging
Non-inferiority of Belotero® Basic Versus Juvéderm® Ultra 3
This study will investigate the non-inferiority of Belotero® Basic versus Juvéderm® Ultra 3 in the treatment of nasolabial folds
- Conditions
- Physiological Stress, Disorder of Aging, Skin Diseases, Wrinkles
- Trial name
- NCT01305187
- Testing
- Hyaluronic Acid Filler
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Dermal Filler, Volume Deficiency of the Midface
An Interventional Study to Evaluate the Safety and Performance of Crosslinked Hyaluronic Acid Hydrogel
The aim of this interventional, pre-market, double- blinded, controlled, two stages study is to evaluate the performance and safety of Crosslinked Hyaluronic Acid (CLHA) Hydrogel (with and without Lidocaine) for the Treatment of…
- Trial name
- NCT05853224
- Testing
- Crosslinked Hyaluronic Acid (CLHA) Hydrogel with and without Lidocaine
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biopolimeri Srl
Skin Condition, Hair Fragility
Assessment of Anti-aging Efficacy of Marine Collagen Peptides
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
- Conditions
- Skin Condition, Hair Fragility, Nails, Ingrown
- Trial name
- NCT06306105
- Testing
- Marine Collagen Peptides
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Hyperpigmentation, Photodamaged Skin
A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging
This open-label, multi-center clinical trial was conducted to evaluate the dual skincare regimen of vitamin C serum and moisturizing sunscreen SPF 45 to improve facial hyperpigmentation and photodamage after 12 weeks of twice…
- Conditions
- Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
- Trial name
- NCT05423873
- Testing
- Gentle Cleansing Lotion, Revision Skincare
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Healthy
Behavioral and Physiological Effects of Visual Training
The primary objective of this study is to evaluate the learnability of a 3 week, 40 minutes per day, 5 day per week, computer-based visual training exercise by healthy mature individuals undergoing normal aging.
- Trial name
- NCT00526942
- Testing
- SAAGE-designed, visual memory-based cognitive training
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Aging, Frailty
Mitophagy and Autophagy in Elderly Subjects
In recent years, evidence has shown that mitochondrial dysfunction plays an important role in the development of age-related muscle decline that may lead to frailty.
- Conditions
- Aging, Frailty, Mitophagy
- Trial name
- NCT02472340
- Testing
- Muscle Biopsy
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Aging
Evaluation of the Safety and Efficacy of Profhilo® Structura
Profhilo® Structura is composed of a buffered saline solution of high molecular weight (H-HA) and low molecular weight (L-HA) hyaluronic acid.
- Trial name
- NCT06719154
- Testing
- Profhilo Structura
- Where
- 3 sites in France, Poland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Acne, Adult
Study To Investigate If Embody's Retinol Gummies Improve The Early Signs Of Skin Aging And Overall Skin Health
The Embody retinol study is a single-arm clinical trial on skin aging prevention and adult acne. The purpose of this study is to determine the effect of a retinol gummy in adults aged 18-45 on skin aging and overall skin health.
- Trial name
- NCT04884516
- Testing
- Retinol gummy
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Embody Beauty, Inc.
Skin Condition
Fermented Grape Combined With Fruits and Vegetables Drink on Anti-aging and Anti-inflammatory
60 subjects were recruited and divided into placebo group and fermented grape drinks group.
- Trial name
- NCT04805697
- Testing
- fermented grape drinks
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Performance Characteristics of Mesofiller Aox for the Correction of Mild and Moderate Facial Wrinkles.
The investigation is a single centre, interventional, prospective, non-randomized, open-label, uncontrolled, single arm, un-blinded investigation for evaluation of safety and performance of the medical device M-AOX-2021 in the…
- Trial name
- NCT06486740
- Testing
- mesofiller aox
- Where
- Bulgaria
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Skin Aging
Pilot Study to Evaluate the Safety and the Efficacy of the Matrix and Cells Obtained by the AmeaCell® Device and Intended for the Filling of Wrinkles on the Face.
The purpose of this study is to evaluate the filling using the Matrix and Cells, obtained by the Ameacell® device from autologous adipose tissue and intended for the filling of wrinkles on the face.
- Trial name
- SKINMAT (NCT03529292)
- Testing
- AmeaCell
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Symbioken
Hyperpigmentation, Skin Aging
Identification of Gene Biomarkers in Aging Skin
This study is a blinded, prospective, single-center, clinical study conducted in Japanese female subjects between the ages of 20-75 years.
- Trial name
- NCT00884936
- Where
- Japan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Interleukin Genetics, Inc.
Hyperpigmentation, Melasma
Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions
Randomized clinical trial to assess the effectiveness and tolerability of Mela B3 serum in combination with 35% glycolic acid peel vs.
- Conditions
- Hyperpigmentation, Melasma, Solar Lentigo, Peeling
- Trial name
- NCT07429786
- Testing
- Glycolic acid peel alone, MelaB3 serum
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Hair Loss, Skin Laxity
Nourishing Hair, Skin & Nails Supplement Study (Derm Aid)
A 90 day eight arm virtual interventional study looking at the impact of various supplement formulations for improves in hair, skin \& nail health via self report, and dermatology assessment via remote dermatologist assessment.
- Conditions
- Hair Loss, Skin Laxity, Cosmetic Acne, Nails; Soft
- Trial name
- NCT04249128
- Testing
- Vegetarian Collagen, Keratin, Ceramides
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ProofPilot
Skin Aging on Face, Skin Care Dermocosmetics
Efficacy of Topical Niacinamide Riboside on the Signs of Facial Skin Aging
Niacinamide riboside (topical NR, also known as nicotinamide riboside) is an endogenous compound and a precursor (building block) to the essential cellular co-enzyme, nicotinamide adenine dinucleotide (NAD+).
- Conditions
- Skin Aging on Face, Skin Care Dermocosmetics, Skin Care, Fine Lines and Wrinkles
- Trial name
- NR-RADIANCE (NCT07774000)
- Testing
- Topical niacinamide riboside
- Where
- South Africa
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.