Clinical trials: Normal Physiology
Normal Physiology
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Background: Transcranial magnetic stimulation (TMS) of the brain has been used to change the activity and connections in the brain to improve memory.
- Trial name
- NCT04694131
- Testing
- TMS
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Normal Physiology
Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRI
Background: Dopamine (DA) is a chemical signal in the brain linked to learning, memory, and habits. Stimulant drugs like methylphenidate can increase DA in the brain. Researchers want to measure DA with and without this drug.
- Trial name
- NCT03326245
- Testing
- Methylphenidate Pill, Intravenous methylphenidate
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Normal Physiology
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids
Background: The immune system defends the body against bacteria and other harmful invaders. But it can overact and attack healthy cells by mistake.
- Trial name
- NCT02798523
- Testing
- Methylprednisolone sodium succinate(Solu-Medrol), Topical methylprednisolone (Advantan emulsion 0 /1%)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Normal Physiology
Sensory Afferents for Deep Pressure Sensation
Background: Much is known about how people perceive light touch, temperature, and pain. But less is known about how deep pressure is perceived. Deep pressure is an important part of many touch therapies, like massage therapy.
- Trial name
- NCT03937778
- Testing
- Deep pressure block
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)