Clinical trials: Normal Weight Adults
Healthy, Normal Weight
Childhood Metabolic Markers of Adult Morbidity in Blacks
Blacks are at increased risk for obesity, type 2 diabetes mellitus and cardiovascular disease. A common pathogenetic link among these entities is insulin resistance/hyperinsulinemia.
- Conditions
- Healthy, Normal Weight, Overweight
- Trial name
- NCT01312051
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Psoriasis, Metabolic Syndrome
Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome
This study was a randomized, open-label, parallel-group, active comparator controlled study with two treatment arms designed to answer the question whether the combination of Secukinumab with lifestyle intervention could…
- Trial name
- METABOLYX (NCT03440736)
- Testing
- Secukinumab, Life-style intervention
- Where
- 75 sites in Germany
- Volunteers
- 781 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
Moving Forward: A Weight Loss Intervention for African-American Breast Cancer Survivors
This is a randomized intervention study to examine the effects of the Moving Forward Guided Weigh Loss Intervention compared to a self-guided weight loss program on BMI and behavioral, biological, and psychosocial outcomes in…
- Trial name
- NCT02482506
- Testing
- MF-WLP, SG-WLP
- Volunteers
- 240 people
- Sponsor
- Medical College of Wisconsin
Ewing Sarcoma, Osteosarcoma
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
The purpose of the study was to investigate whether functional MRI imaging (diffusion weighted imaging) is useful for monitoring the therapeutic response of bone sarcomas in children and young adults.
- Trial name
- FUBEO (NCT01780779)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Overweight, Obesity
Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk
The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity.
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Healthy
- Trial name
- PINEAPPL (NCT06355544)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Integrative Phenomics
Obesity
Effects of Sweetness on Neurocognitive Responses, Glycemia and Food Intake
This study aims to examine potential differences in neurocognitive responses to food-related cues, physiological and appetite responses as well as subsequent energy intake following the consumption of preloads differing in…
- Trial name
- NCT03711084
- Testing
- Natural high potency sweetener from leaf extract, Glucose, Sucrose
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Healthy Participants Study, Overweight and Obese Adults
A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity
The goal of this clinical trial is to learn about the safety and tolerability of drug ZP6590 and to learn how the body processes the drug ZP6590 in adults.
- Conditions
- Healthy Participants Study, Overweight and Obese Adults, First in Man Study to Evaluate Initial Safety
- Trial name
- NCT07721597
- Testing
- ZP6590, solution for injection
- Where
- Germany
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Zealand Pharma
Cancer
Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer
RATIONALE: Cyproheptadine hydrochloride may prevent weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine is more effective than a placebo in preventing weight loss in young patients…
- Trial name
- NCT01132547
- Testing
- cyproheptadine hydrochloride
- Where
- 14 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of South Florida
Obesity
The Incidence and Factors of Brown Adipose Tissue in Chinese
Previous studies have shown active brown adipose tissue (BAT) is present in adults and may play important roles in regulating energy homeostasis.
- Trial name
- NCT01381042
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Huashan Hospital
Hunger
The Effect of Television Watching on Liking of Food
The purpose of the study is to investigate the effect of television viewing on liking of food.
- Trial name
- NCT02505490
- Testing
- Television, No Television
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity, Normal Physiology
Energy Expenditure Responses to Different Temperatures
Background: The way that the body burns calories is known as energy expenditure. Some studies show that when we are cold, we burn more calories to keep our bodies warm.
- Trial name
- NCT01568671
- Testing
- Room temperatures
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy
Leptin and Endothelial Function
The purpose of this trial was to determine if injections of leptin would improve vascular function in normal-weight, healthy volunteers.
- Trial name
- NCT00121433
- Testing
- leptin
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ultrasound, Sarcopenia
Muscle Quality and Subcutaneous Adipose Tissue in the Rectus Femoris and Rectus Abdominis Muscles: Ultrasound Evaluation and Functional Correlation in Older Adults
The goal of this observational, cross-sectional study is to examine the relationship between body composition and muscle quality in women over the afe of 65.
- Conditions
- Ultrasound, Sarcopenia, Obesity
- Trial name
- NCT07069777
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Salamanca
Healthy Normal Weight
Meal Texture and Satiety
The aim of the present study is to compare the nutritional compensation between iso-caloric meals of various textures (liquid vs solid) in health young adults.
- Trial name
- FEED (NCT04041752)
- Testing
- SOLID, LIQUID_P, LIQUID_L
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma
This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with…
- Conditions
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Trial name
- NCT01825902
- Testing
- fluorine F 18 fluorothymidine, fludeoxyglucose F 18, positron emission tomography
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Obesity, Type 2 Diabetes
Impacts of Intermittent Fasting on Energy Balance and Associated Health Outcomes
Obesity is a global concern with links to conditions such as diabetes. Historically, these conditions have been managed by reducing energy intake on a daily basis, which is often hampered by low adherence rates and compensatory…
- Trial name
- NCT02498002
- Testing
- Physical Activity Monitoring (Actiheart), Energy Intake Monitoring, Body Weight Monitoring
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bath
Normal Weight Adults, Adults With Obesity
Validation of a French-version of the Leeds Food Preference Questionnaire in Normal Weight and Patients With Obesity
While Food reward is an important component of the appetite control to consider, there is actually no tool that has been developed in French to perform its evaluation.
- Trial name
- LFPQ-F (NCT04041830)
- Testing
- Visit 1, Visit 2
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
The purpose of this clinical trial is to find out whether one type of fish oil works better than another at improving metabolic health in people who are at high risk of developing type 2 diabetes.
- Conditions
- Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity & Overweight
- Trial name
- END-T2D (NCT07575438)
- Testing
- Fish Oil, Corn oil control
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Mood, Eating Patterns
The Effect of Portion Sizes on Mood
The purpose of this study is to investigate whether different portion sizes will effect overall mood.
- Trial name
- NCT01725425
- Testing
- Control, Increase Portion Size, Decrease Portion Size
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity
Impact of Whey and Soy Protein Ingestion in Conjunction With Energy Restriction in Overweight/Obese Individuals
It is known that dieting (restricted energy intake) without resistance training leads to a reduced metabolic rate, and the loss of both fat and muscle mass.
- Trial name
- NCT01530646
- Testing
- Weight loss, Soy, Whey
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McMaster University