Clinical trials: Normative
Uterine Fibroid
Implementation of Uterine Fibroid Option Grid Patient Decision Aids Across Five Organizational Settings
UPFRONT is a study that aims to use two implementation frameworks - the Consolidated Framework for Implementation Research and the Normalization Process Theory - to guide the implementation of a uterine fibroid patient decision…
- Trial name
- UPFRONT (NCT03985449)
- Testing
- Uterine Fibroid Option Grid encounter patient decision aid (text only), Uterine Fibroid Option Grid encounter patient decision aid (text + Pictures), Uterine Fibroid Option Grid encounter patient decision aid (online)
- Where
- United States
- Volunteers
- 748 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alcohol Drinking
Evaluating Within-Person and Between-Person Effects Of A Personalized Normative Feedback Intervention On Drinking As They Are Moderated By Self-Determination
This study evaluates within-person and between-person effects of a personalized normative feedback intervention and injunctive norms as they are altered by self-determination in heavy drinkers.
- Trial name
- NCT03583515
- Testing
- Alcohol-Specific Personalized Normative Feedback, Social Media Personalized Normative Feedback
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Houston
Healthy
The Influence Body Position and Axial Load on Spinal Stiffness
The objective of this study is to examine the influence of body position and additional axial load on spinal stiffness in young healthy adults.
- Trial name
- NCT03495843
- Testing
- Spinal stiffness
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Balgrist University Hospital
Obesity, Insulin Resistance
Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth
Vitamin D deficiency is extremely common in obese youth. In our obese population followed in the Endocrinology clinic at Children's Medical Center Dallas, vitamin D levels were inversely correlated with a measure of insulin…
- Conditions
- Obesity, Insulin Resistance, Vitamin D Deficiency
- Trial name
- NCT02168660
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Perrin C White, MD
Urinary Tract Obstruction
A Comparative Study of Normalized Residual Activity and Standard Parameters in 99mTc-DTPA Diuretic Renography:
The present study aims to compare the diagnostic performance of Normalized Residual Activity (NORA) with conventional renographic parameters obtained from 99mTc-diethylenetriamine pentaacetic acid (99mTc-DTPA) diuretic renography…
- Trial name
- NCT07811388
- Testing
- 99m Tc-DTPA, Furosemide
- Volunteers
- 57 people
- Sponsor
- Assiut University
Aging, Dementia Alzheimers
Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE)
Scalp to cortex distance (SCD), as a key technological parameter of brain stimulation, has been highlighted in the guidelines of non-invasive brain stimulation.
- Conditions
- Aging, Dementia Alzheimers, Parkinson Disease, Dementia Frontotemporal
- Trial name
- NCT05967390
- Testing
- Transcranial Magnetic Stimulation
- Where
- Hong Kong
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Hyperphosphatemia, End Stage Renal Disease
A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HP
The study is designed to evaluate the ability of tenapanor alone or in combination with sevelamer to achieve serum phosphorus concentration (sP) within the population reference range (sP >2.5 and ≤4.5 mg/dL) in patients with…
- Trial name
- NORMALIZE (NCT03988920)
- Testing
- Tenapanor, Sevelamer Carbonate
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Ardelyx
Cortical Development Malformation, Multiparametric Magnetic Resonnance Imaging
Normative Brain Volume Profiles From Multicenter Fetal MRI
Fetal brain MRI is an essential diagnostic tool to inform parents about the prognosis of abnormalities detected on routine ultrasound.
- Conditions
- Cortical Development Malformation, Multiparametric Magnetic Resonnance Imaging, Brain Cortical Thickness, Prenatal Diagnosis
- Trial name
- MULTINORMFET (NCT06081036)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,423 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Healthy
Development, Implementation and Initiation of Normative Database Quantitative Ultra High Field MRI Paramaters
The Centre for Magnetic Resonance in Biology and Medicine (CRMBM, UMR-CNRS 7339 AMU) obtained funding for a whole body NMR imaging at 7.
- Trial name
- NCT02402751
- Testing
- acquisition of normative database with ultra high field MRI, MRI
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Children, Only, Vestibular Function
Normative Data of Vestibular and Postural Function in Danish Children
The goal of this age-based cohort study is to provide normative data of vestibular function in the general Danish pediatric population.
- Trial name
- VASIC (NCT06229730)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Pregnant Women, First Pregnancy
Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnant Women
Pregnancy causes the development of biomechanical adaptations in the musculoskeletal system, especially in the lumbopelvic region.
- Trial name
- NCT05335330
- Testing
- Evaluation of biomechanics and viscoelastic properties of Thoracolumbar fascia
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Alzheimer's Disease
Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults
Biomarkers of Alzheimer's disease (AD) occupy an essential place in recently formulated diagnostic criteria for AD where their role is to identify the pathophysiological processes underlying cognitive impairment or to predict…
- Trial name
- NCT01609335
- Testing
- F-18 FDG, C-11 PiB
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
College Drinking, Underage Drinking
Revolutionizing Normative Re-education
Personalized Normative Feedback (PNF), the most widely-used college alcohol intervention approach, suffers from several limitations innovatively remedied in the current proposal through CampusGANDR, a smartphone-based app for…
- Conditions
- College Drinking, Underage Drinking, Alcohol Use Disorder
- Trial name
- GANDR (NCT04356261)
- Testing
- Gamified Personalized Normative Feedback
- Where
- United States
- Volunteers
- 1,143 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Advanced Heart Failure, Left Ventricular Assist Devices
Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients
The TARGET trial is a prospective, single-center, randomized, open-label, active-controlled inequality clinical trial designed to evaluate the safety and efficacy of low-intensity anticoagulation therapy (target INR 1.5-2.0)…
- Conditions
- Advanced Heart Failure, Left Ventricular Assist Devices, Anticoagulation Treatment, Bleeding Complications
- Trial name
- TARGET (NCT07081035)
- Testing
- Warfarin (low-intensity anticoagulation), Warfarin (standard anticoagulation)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center
Fall, Old Age; Debility
Normative Data of Dynamic Gait Index and 5 Time Sit to Stand Test Among Elderly Population
The goal of this observational study is to measure the normative data for dynamic gait index and 5 time sit to stand test in elderly population.
- Trial name
- NCT05651412
- Testing
- Dynamic gait index and 5 time sit to stand test
- Where
- 2 sites in Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Secondary Hypogonadism
Phase III Study to Evaluated Morning Testosterone Normalization in Men With Secondary Hypogonadism
The purpose of ZA-301 is to determine the effects of Androxal on morning testosterone and reproductive status in younger overweight men with acquired hypogonadotropic hypogonadism (confirmed morning T<300 ng/dL) and normal sperm…
- Trial name
- NCT01532414
- Testing
- Androxal
- Where
- 23 sites in United States
- Volunteers
- 151 people
- Sponsor
- Repros Therapeutics Inc.
Focal Segmental Glomerulosclerosis
Treating to Reduce Albuminuria and Normalize Hemodynamic Function in Focal ScLerosis With dApagliflozin Trial Effects
Patients with Focal Segmental Glomerulosclerosis (FSGS) constitute an increasing proportion of the total glomerulonephritis (GN) patient cohort in North America while FSGS is a risk factor for end stage renal failure.
- Trial name
- TRANSLATE (NCT02585804)
- Testing
- Dapagliflozin
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Retinal Vascular, Retina
Normative Data Collection Study of the Zilia Ocular for the Measurement of Oxygen Saturation in the Retina
Mainstream oximetry devices use two-wavelength systems to photograph the retina and estimate the oxygen saturation levels in the retinal vessels by comparing light absorption in the blood of the vessels at the selected…
- Trial name
- NCT04408677
- Testing
- Zilia Ocular
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Zilia Inc.
Glaucoma
Building a Database of Results From People Without Eye Problems
The purpose of this study is to build a database of results from a new test that measures contrast sensitivity (the Spaeth-Richman Contrast Sensitivity Test (SPARCS)).
- Trial name
- SPARCS (NCT02627339)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Advanced Primary Lung Adenocarcinoma
The Use of CT Perfusion to Determine the Normalization Window Period in the Treatment of Advanced Primary Lung Adenocarcinoma With Endostar
To evaluate the change of blood perfusion before/after the use of Endostar, discuss the time sequence of Endostar TM in treating advanced lung adenocarcinoma in normalization window period.
- Trial name
- NCT01564329
- Testing
- endostar
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd