Clinical trials: Normative
Hypertension
Selara Drug Use Investigation (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety information of Eplerenone on patients with hypertension related to their appropriate use in daily practice.
- Trial name
- ESSENCE (NCT00749775)
- Testing
- Selara
- Volunteers
- 3,338 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Secondary Hypogonadism
Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism
The Purpose of the study is to determine the effects of Androxal on morning testosterone and reproductive status in men with secondary hypogonadism(confirmed morning Testosterone less than 250 ng/dL), compared to changes with…
- Trial name
- NCT01270841
- Testing
- topical testosterone, Androxal
- Where
- 18 sites in United States
- Volunteers
- 83 people
- Sponsor
- Repros Therapeutics Inc.
Management of Anticoagulation
Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care
Patients who receive a mechanical heart valve to replace a diseased heart valve must take an anticoagulation medicine the rest of their lives, and monitor their level of anticoagulation.
- Trial name
- NCT00703963
- Testing
- INRatio monitor by Hemosense, Usual Care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anticoagulation
Prospective Evaluation of an Extended Interval of INR Follow-up in a VA Anticoagulation Service
The purpose of this study is to determine the feasibility, safety, and acceptability of implementing an extended interval of INR follow-up in Veterans on a stable dose of warfarin in the Anticoagulation Clinic at the William S.
- Trial name
- NCT02392104
- Testing
- Warfarin
- Volunteers
- 51 people
- Sponsor
- William S. Middleton Memorial Veterans Hospital
Puberty
The COPENHAGEN Puberty Study
By clinical examinations and withdrawing of blood samples from a large number of healthy Danish children, this study will reveal if age of pubertal onset is declining.
- Trial name
- NCT01411527
- Where
- Denmark
- Volunteers
- 1,957 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke
Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke
Despite the functional importance, fingertip forces are rarely explicitly addressed with feedback in therapy. This gap in treatment is due to a lack of tools to provide explicit feedback on patients' volitional finger force…
- Trial name
- NEAD (NCT03995069)
- Testing
- 3D, 1D
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- VA Office of Research and Development
Hypovitaminosis D
Rapid Normalization of Vitamin D in Critically Ill Children: A Phase II Dose Evaluation Randomized Controlled Trial
Documented roles for vitamin D in calcium homeostasis, cardiovascular and respiratory health, inflammation, innate immunity, and neuromuscular function have led to the hypothesis that deficiency might represent a modifiable risk…
- Trial name
- VITdAL-PICU (NCT02452762)
- Testing
- Vitamin D3
- Where
- 4 sites in Austria, Canada and 1 more
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Eastern Ontario
Hyperkalemia
A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8
The study is designed to determine if ZS 10g administered up to three times over 10h added to insulin and glucose in patients presenting with hyperkalemia will prove tolerable and efficacious.
- Trial name
- ENERGIZE (NCT03337477)
- Testing
- Sodium Zirconium Cyclosilicate(ZS), Insulin, Glucose
- Where
- 25 sites in United States, Denmark and 2 more
- Volunteers
- 70 people
- Sponsor
- AstraZeneca
Multiple Sclerosis
Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS
In an individual with MS the central nervous system (CNS) is over-protective and causes the threshold for stretch reflex and muscle tightness to be set lower than normal.
- Trial name
- NCT04942938
- Testing
- Neubie
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- CommonSpirit Health
Acromegaly
Effects of Sandostatin LAR® in Acromegaly
This study aims primarily to determine the effect Insulin-like Growth Factor 1 (IGF-1) normalization into current IGF-I normal ranges with Sandostatin LAR® therapy on biochemical metabolic, cardiovascular and body composition…
- Trial name
- NCT01424241
- Testing
- Sandostatin LAR
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Columbia University