Clinical trials: Normative, open to volunteers
Pediatric ALL, Adolescent
Pediatric Normative Markerless Movement Analysis
The objective of this project is to collect baseline data from a normative population of 20 children that gender and age matches the population of patients expected to be treated by Mary Bridge Children's Research \& Movement Lab.
- Trial name
- NCT06249880
- Testing
- Observation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MultiCare Health System Research Institute
HIV (Human Immunodeficiency Virus), Alcohol Misuse
PNF RCT to Decrease Alcohol Use and Increase HIV Prevention
Randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among adolescents and…
- Conditions
- HIV (Human Immunodeficiency Virus), Alcohol Misuse, STI
- Trial name
- NCT07731932
- Testing
- PNF - HIV norms, PNF - Alcohol use norms, PNF - HIV and alcohol use norms
- Where
- Uganda
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Alcohol Use
CPNF Intervention Development and Testing
The project will develop brief interventions that allow participants to customize which groups they receive feedback for in relation to things such as drinking norms for younger or older students, student athletes, etc.
- Trial name
- Project SHIFT (NCT07036198)
- Testing
- Customizable personalized normative feedback (CPNF), Personalized normative feedback (PNF), Attention-Matched Control (AMC)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Washington
Tongue Cancer
Normative Ranges of Lingual Strength and Endurance and the Impact of the IOPI Lingual Strength Trainer on Quantitative Functional Outcomes and Patient-Reported Outcomes After Partial Glossectomy or Hemiglossectomy for Oral Tongue Cancer, An Unblinded: Randomized Pilot Study
The purpose of this study is to learn more about tongue strength and endurance by using the Iowa Oral Performance Instrument (IOPI). The IOPI is a device that measures tongue pressure.
- Trial name
- NCT07124520
- Testing
- Iowa Oral Performance Instrument (IOPI)
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lower Limb Amputation Below Knee (Injury)
Restoration of Normative Postural Control
The objective of this proposal is to investigate the effects of training to use direct electromyographic (dEMG) control of a powered prosthetic ankle on transtibial amputees'. The aimed questions to answer: 1.
- Trial name
- NCT06452186
- Testing
- direct EMG controlled prosthetic ankle, PT guided prosthetic training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- North Carolina State University
Lung Cancer
TROP2 NMR Concordance Study
This is a two-stage, multi-center study to compare concordance of Local solution and Mixed solution with a Reference solution in testing TROP2 NMR in untreated advanced NSCLC patients, as well as clinical application and…
- Trial name
- NCT07624318
- Testing
- Reference solution, Mixed solution, Local solution
- Where
- 4 sites in China
- Volunteers
- 3,400 people
- Sponsor
- AstraZeneca
Collecting Normative Data of Ulnar Nerve CSA
MULTICENTER ULNAR NERVE ULTRASONOGRAPHIC and NEUROPHYSIOLOGICAL STUDY: NORMATIVE DATA COLLECTION
The study population will include a total of 500 subjects, selected from outpatients accessing the Neurophysiology Service for a neurophysiological study of the upper limbs.
- Trial name
- US-ULN (NCT06818162)
- Testing
- normative data
- Volunteers
- 500 people
- Sponsor
- IRCCS San Raffaele
Healthy Participants
Supervision of Clinicians in Oncology by Psycho-oncologists : Evaluation
Communication in the oncology setting involves cognitive as well as emotional challenges for both clinicians and patients, and interactional dimensions that emerge in their encounter.
- Trial name
- SCOPE (NCT07268378)
- Testing
- Supervision session
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
ACL Injury, Anterior Cruciate Ligament Injuries
Baseline ACL Injury Risk Screening and Normative Data
This is a prospective, observational cohort study aimed at establishing a database of normative biomechanics for healthy athletes and surveying these athletes for 12 months following baseline testing for the occurrence of new…
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
- Trial name
- NCT06635668
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Sanford Health
Lumbar Canal Stenosis, Lumbar Spinal Stenosis
Is it Really Necessary Going All Over the Top in Patients With Symptomatic Lumbar Spinal Stenosis?
The goal of this clinical trial is to evaluate the theory of epidural pressure by comparing a surgical procedure that aims to perform less bone resection compared to conventional surgery in patients with lumbar spinal stenosis.
- Conditions
- Lumbar Canal Stenosis, Lumbar Spinal Stenosis, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07026305
- Testing
- Pressure-guided laminectomy (PGL), Laminectomy without pressure guidance (LWPG)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Epilepsy
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
Objectives: The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images based on pre- and postsurgical localization of epileptic foci in patients…
- Trial name
- NCT02107989
- Testing
- MRI, MEG
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lower Urinary Tract Symptoms (LUTS)
Establishing Normative Urodynamics Parameters for the Glean Urodynamics System in Healthy Adults
A prospective, open-label, single arm interventional trial to establish normative reference ranges for urodynamics parameters in healthy adult participants using using the Glean Urodynamics System.
- Trial name
- NCT07485205
- Testing
- Glean Urodynamics System
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bright Uro
Vitamin D 25-Hydroxylase Deficiency, Lymphoma Non-Hodgkin
High-Dose vs Standard Ergocalciferol for Vitamin D Normalization in Aggressive Non-Hodgkin Lymphoma
The goal of this clinical trial is to evaluate whether a high-intensity loading dose of ergocalciferol (vitamin D2) can normalize blood vitamin D levels more rapidly and safely than standard weekly dosing in patients with newly…
- Trial name
- NCT07366450
- Testing
- High-Dose Loading Ergocalciferol, Standard Weekly Ergocalciferol
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Anorexia Nervosa in Remission, Bulimia Nervosa
Therapeutic Ketogenic Diet in Anorexia Nervosa
This study will investigate the effects of therapeutic ketogenic diet (TKD) on eating behavior including drive to restrict, body dissatisfaction, mood and anxiety in individuals with anorexia nervosa who have been weight…
- Conditions
- Anorexia Nervosa in Remission, Bulimia Nervosa, Anorexia Nervosa
- Trial name
- NCT06000774
- Testing
- Therapeutic Ketogenic Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Hyperandrogenism, Polycystic Ovary Syndrome
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary…
- Conditions
- Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
- Trial name
- CBS010 (NCT04723862)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diabetes Mellitus Type 2 in Obese
Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction
This is a randomized controlled trial to determine whether a low-carbohydrate (LC) diet can lead to normalized blood glucose levels in patients with short duration of type 2 diabetes (T2D).
- Trial name
- CarborCal (NCT05801614)
- Testing
- Low carb diet
- Where
- Sweden
- Volunteers
- 286 people
- Sponsor
- Region Stockholm
Healthy Adults
Normative Data for Cardiorespiratory Fitness in Healthy Adults
Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle…
- Trial name
- NDFCFIHAUTQCST (NCT07275619)
- Where
- Pakistan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Advanced Heart Failure, Left Ventricular Assist Devices
Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients
The TARGET trial is a prospective, single-center, randomized, open-label, active-controlled inequality clinical trial designed to evaluate the safety and efficacy of low-intensity anticoagulation therapy (target INR 1.5-2.0)…
- Conditions
- Advanced Heart Failure, Left Ventricular Assist Devices, Anticoagulation Treatment, Bleeding Complications
- Trial name
- TARGET (NCT07081035)
- Testing
- Warfarin (low-intensity anticoagulation), Warfarin (standard anticoagulation)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center