Clinical trials: Normoxia, active
Normoxia, Intermittent Moderate Hypoxia
Brain Connectivity and Corticospinal Excitability in Response to Moderate Hypoxia
Hypoxia, defined as a reduction in the availability of oxygen, induces significant physiological adaptations. While the deleterious effects of severe and chronic hypoxia are well documented, several studies indicate that moderate…
- Conditions
- Normoxia, Intermittent Moderate Hypoxia, Continuous Moderate Hypoxia
- Trial name
- NEUROXIE (NCT07516028)
- Testing
- Moderate hypoxia, Normoxia, Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Critical Illness, Wounds and Injury
Strategy to Avoid Excessive Oxygen in Major Burn Patients
The objective is to determine the effectiveness of a multimodal educational intervention to reduce supplemental oxygen use in major burn patients.
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Trial name
- SAVE-O2 (NCT04534972)
- Testing
- Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg)
- Where
- 6 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- University of Colorado, Denver
Critical Illness, Wounds and Injury
Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients
The objective is to determine the effectiveness of a multimodal educational intervention to reduce supplemental oxygen use in critically injured patients.
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Trial name
- SAVE-O2 (NCT04534959)
- Testing
- Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg)
- Where
- 8 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- University of Colorado, Denver
High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N)
Normobaric Hypoxia as a Strength Training Intensity Amplifier in Ice Hockey Players: Effects on Anaerobic Performance and Muscle Contraction Properties
The goal of this research study is to investigate the effects of resistance training performed under normobaric hypoxia (simulated altitude conditions) on anaerobic performance, lactate clearance, and muscle contractility in…
- Conditions
- High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N), High-intensity Strenght Training in Normobaric Hypoxia (H-H), Low-intensity Strenght Training in Normobaric Hypoxia (L-H)
- Trial name
- NCT06930027
- Testing
- Resistance Training (High-Intensity), Resistance Training (Low-Intensity), Normobaric Hypoxia
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Obstructive Sleep Apnea of Adult, Hypoxia, Brain
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).
- Conditions
- Obstructive Sleep Apnea of Adult, Hypoxia, Brain, Sleep Apnea, Sleep Disorder
- Trial name
- NCT03255408
- Testing
- Drug Lowering Cerebral Blood Flow (CBF) and Normoxia Sleep, Drug Lowering CBF and Intermittent Hypoxia Sleep
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary