Clinical trials: Nuclear Cataract
Cataract With a Nuclear Sclerosis Grade Between 1 to 3
Zero CDE Technique for Lens Removal During FLACS
The Zero CDE (cumulative dissipated energy) technique facilitates cataract removal with no or minimal phaco energy. This is facilitated by a femtosecond laser, which pre-divides the cataractous lens nucleus into multiple small…
- Trial name
- NCT07404293
- Testing
- Femtosecond laser-assisted cataract surgery using Zero CDE
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Bochner Eye Institute
Epiretinal Membrane, Macular Hole
Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal
The purpose of this trial is to compare the ability of two doses of OT-551 ophthalmic solution and drug-free solution to safely and effectively prevent or delay the progression of nuclear cataracts that frequently develop as a…
- Trial name
- NCT00333060
- Testing
- OT-551 ophthalmic solution
- Where
- 16 sites in United States
- Volunteers
- 164 people
- Sponsor
- Othera Pharmaceuticals
Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery
A Randomized Study of Gas Bubble Technique in Cataract Surgery
To investigate the efficiency and safety of using "Gas Bubble Technique" to reduce corneal endothelial damage in hard nucleus cataract patients.
- Trial name
- NCT06636279
- Testing
- Gas bubble technique
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sichuan Provincial People's Hospital
Brown Cataract
Modified Nuclear Phacoemulsification in Brown Cataract
Irrigation of the nucleus with saline for 30 seconds after creating the central groove.
- Trial name
- NCT07252154
- Testing
- phacoemulsification
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Fuchs Dystrophy, Cataract
The Evaluation of Balanced Salt Solution During Cataract Surgery
This study aims to identify if the use of BSS PLUS® Sterile Intraocular Irrigating Solution as an irrigation solution leads to improved corneal outcomes vs BSS® Sterile Irrigating Solution in more compromised corneas.
- Trial name
- NCT05853978
- Testing
- BSS Plus, BSS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Adam Fedyk, MD, FACS
Cataract
Cataract Surgery to Obtain Human Lens Material for the Study of Nuclear Cataracts
Cataract, in which the lens of the eye is opacified, is the major cause of blindness. This study will examine protein material of the lens called crystallins to try to determine what causes nuclear cataracts, a type of cataract…
- Trial name
- NCT00001613
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Anterior Chamber Inflammation, Ocular Pain
A Retrospective Review of DEXTENZA 0.4 mg inseRt Following Corneal Transplant or Cataract Surgery
A Retrospective Review of Pain and Inflammation Resolution Outcomes in Patients Who Received DEXTENZA Intracanalicular Dexamethasone (0.4 mg) Insert Prior to or Following Corneal transplant or Cataract surgery
- Conditions
- Anterior Chamber Inflammation, Ocular Pain, Corneal Edema, Corneal Defect
- Trial name
- NCT04975971
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nicole Fram M.D.
Cataract Surgery, Cataract and Fuchs Endothelial Corneal Dystrophy
Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy
The purpose of the study is to investigate whether there is a difference in BCVA in patients who receive one of the following two surgeries: intervention group (arm 1) cataract surgery alone and control group (arm 2) cataract…
- Trial name
- ETCF (NCT06425666)
- Testing
- Intervention group /arm 1 (Cataract surgery alone), Control group /arm 2: Corneal transplantation as Descemet Membrane Endothelial Keratoplasty (DMEK) in combination with cataract surgery (triple-DMEK)
- Where
- 4 sites in Denmark, Germany and 2 more
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Nuclear Cataract
Microinterventional Endocapsular Nuclear Fragmentation Assisted Cataract Surgery
Rationale: In cataract surgery, fragmentation of a hard nucleus requires relatively much ultrasound energy. It is suspected that the level of energy used is associated with the degree of corneal endothelial loss.
- Trial name
- NCT05736042
- Testing
- Lens fragmentation
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Oogziekenhuis Rotterdam