Clinical trials: Nulliparous
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postpartum Disorder
Bladder Displacement During Abdominal and Pelvic Floor Exercises
This study evaluates the bladder base displacements during abdominal and pelvic floor exercises in postpartum women comparing to nulliparous women
- Trial name
- NCT04154527
- Testing
- Pelvic Floor and Abdominal Exercises
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Castilla-La Mancha
Induction of Abortion
Foley's Catheter Balloon for Induction of Mid Trimester Abortion in Nulliparous Women With or Without Tension Applied
Induction of abortion is a hot subject that has complex and emotional controversy. The most common time of abortion is the second trimester which represent about 10-15% of all induced abortions over the world.
- Trial name
- NCT02842164
- Testing
- Tension group, No tension group, Foley catheter Balloon
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Labor, Epidural Analgesia
Effect of Epidural Analgesia on the Length of Labor and Delivery and Fetal Outcomes
The purpose of this study is to determine if there is a difference in the duration of the first and second stage of labor in nulliparous women , with or without epidural analgesia.
- Conditions
- Labor, Epidural Analgesia, Nulliparous
- Trial name
- NCT02396563
- Testing
- epidural analgesia, Ropivacaine
- Volunteers
- 100 people
- Sponsor
- University of Cagliari
ART, Pre-Eclampsia
Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology
This study seeks to validate the hypothesis that nulliparous pregnant women after Assisted Reproductive Technology (ART) are at high risk of preeclampsia and perinatal complications and represent a subgroup for which aspirin…
- Trial name
- APPART (NCT05625724)
- Testing
- Aspirin
- Where
- 21 sites in France
- Volunteers
- 1,164 people
- Sponsor
- University Hospital, Toulouse
Contraception
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
Because of misoprostol's known ability to cause cervical dilation, some family planning providers give their patients a dose of this drug prior to insertion.
- Trial name
- miso (NCT01147497)
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Emory University
Intrauterine Device
Vaginal Dinoprostone Administration Prior to a T380A Intrauterine Device Insertion in Nulliparous Women.
To investigate whether vaginal dinoprostone administered before intrauterine device (IUD) insertion reduces failed insertions, insertion-related complications and pain in nulliparous women.
- Trial name
- NCT03686085
- Testing
- Dinoprostone 3 mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Motor Imagery, Action Observation
Movement Simulation Techniques and Therapeutic Exercise in Young Nulliparous Women
Both motor imagery and action observation training, either alone or in combination with physical practice, have been shown to improve some clinical variables of interest such as strength and motor control.
- Conditions
- Motor Imagery, Action Observation, Therapeutic Exercise
- Trial name
- NCT06090435
- Testing
- Therapeutic exercise plus motor imagery, Therapeutic exercise plus action observation, Therapeutic exercise
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Labor Onset and Length Abnormalities
Effect of Tafoxiparin on Cervical Ripening and Induction of Labor in Term Pregnant Women With an Unripe Cervix
The study is designed as a randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof of Concept Study (section A) with a conditional dose finding follow up (Section B) to Evaluate the Efficacy on Cervical ripening…
- Trial name
- NCT04000438
- Testing
- DF01, PL1
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Pain
Massage for Pain Relief During the Active Phase of Labor
The objective of this research is to evaluate the effect of massage therapy as a resource for pain relief during the active phase of labor.
- Trial name
- NCT01392053
- Testing
- Lumbosacral Massage
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hysteroscopy
Office Hysteroscopy Versus Cervical Probing for Cervical Stenosis
This study aims to estimate if performing a small caliber office hysteroscopic cervical negotiation would succeed to bypass tight markedly stenotic cervix in comparison to blind cervical probing done under general anesthesia.
- Trial name
- NCT03457350
- Testing
- cervical negotiation
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Woman's Health University Hospital, Egypt
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Induction of Labor Affected Fetus / Newborn
Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients
A randomized, prospective trial will be offered to women admitted to the labor floors at Mount Sinai Medical Center for labor induction.
- Trial name
- NCT03348683
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Labour Dystocia
Accelerated Titration of Oxytocin for Nulliparous Patients With Labour Dystocia: ACTION Pilot Study
The ultimate objective is to test the hypothesis that an 'accelerated titration' protocol for labour augmentation with oxytocin reduces the risk of caesarean births relative to a 'gradual titration' protocol.
- Trial name
- ACTION (NCT01397630)
- Testing
- Oxytocin
- Where
- 2 sites in Canada
- Volunteers
- 79 people
- Sponsor
- Ottawa Hospital Research Institute
Labor (Obstetrics)--Complications
Uterocervical Angle Versus Cervical Length as a Predictor of Labor Induction in Term Singleton Pregnancy
Induction of labor is frequently performed in all obstetric clinics. Failed IOL has been defined in many different ways.Bishop scoring, which is a traditional and subjective method, is more frequently evaluated with cervical…
- Trial name
- NCT06558500
- Testing
- Uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Urinary Incontinence, Anal Incontinence
Tridimensional Pelvic Floor Ultrasound and Quality of Life Scores Questionnaires in Nulliparous or Parous Women
Evaluation of the impact of the delivery in the system of suspension and sustentation of pelvic floor, by 3D ultrasound and quality of life questionnaires.nt
- Conditions
- Urinary Incontinence, Anal Incontinence, Sexual Dysfunction, Self Esteem
- Trial name
- NCT03656601
- Testing
- 3D pelvic ultrasound
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Dyspareunia, Pain
Effects of Myofascial Release With and Without Thiele Massage
Dysperunia is caused by chronic discomfort during sexual intercourse causing pain during vaginal intercourse.Sexual pain causes relationship decreasing quality of life following anxiety and depression.Myofascial techniques with…
- Conditions
- Dyspareunia, Pain, Quality of Life
- Trial name
- NCT05834088
- Testing
- Myofascial release techniques, Thiele massage
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Slow Labour Progress
Labour Augmentation by Means of Oxytocin - Obstetric Outcome and Women's Experiences
Slow labour progress is common in nulliparous women and is associated with childbirth complications and negative birth experiences. Oxytocin augmentation is widely used to treat slow labour despite associated risks for the fetus.
- Trial name
- NCT01263158
- Testing
- Expectancy of standard oxytocin treatment
- Where
- Sweden
- Volunteers
- 2,072 people
- Sponsor
- Göteborg University
Pre-eclampsia, Intra-uterine Growth Restriction
Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
The objective of this study is to test the efficacy of low-dose aspirin (160 mg/day), given bedtime and started early during pregnancy (≤ 15 +6 weeks of gestation) in nulliparous pregnant women selected as "high-risk" by the…
- Trial name
- PERASTUN (NCT01729468)
- Testing
- Aspirin
- Where
- 17 sites in France, Martinique
- Volunteers
- 1,106 people
- Sponsor
- University Hospital, Tours
Contraception
Intra Uterine Device Insertion in Nulliparous Women
Over the last several years, more and more women are choosing intrauterine contraception (IUDs) to meet their birth control needs.
- Trial name
- NCT01422226
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver