Clinical trials: Nursing Home
Depression
Medication Treatment for Depression in Nursing Home Residents
This study will examine therapeutic and adverse effects of continuing versus discontinuing antidepressant medication in nursing home residents who have had no more than a single episode of depression and who no longer have…
- Trial name
- NCT00076622
- Testing
- Antidepressant medication, No antidepressant medication
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Pennsylvania
Aging
Cycled Testosterone Therapy to Improve Physical Function in Frail Nursing Home Residents
Frailty is a recognized cause for disability, hospitalization, and mortality in nursing home residents. Testosterone treatment is among the potentially beneficial treatments in addition to resistance exercise for improving muscle…
- Trial name
- NCT02679274
- Testing
- Testosterone
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pain
Shared Decision Making to Improve Palliative Care in the Nursing Home
Twenty-eight percent of Americans over the age of 65 die in a nursing home. Research has found the quality of care of end-of-life care in nursing homes to have many challenges.
- Trial name
- NCT02917603
- Testing
- Web Conferencing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Alzheimer's Disease and Related Dementias
OPTIMAL in NH Residents With Dementia
The purpose of this study is to develop and refine OPTIMAL and evaluate its feasibility, fidelity, and usefulness. The OPTIMAL is designed to teach staff to effectively engage residents in eating using individualized…
- Trial name
- NCT05255068
- Testing
- OPTIMAL
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Iowa
Deficiency of Vitamin D3
Optimizing Vitamin D in the Elderly
Vitamin D deficiency is highly prevalent in older people in the absence of vitamin D supplementation. The limited data available show marked inter-individual variability in response to vitamin D supplementation in very old, frail…
- Trial name
- NCT01554241
- Testing
- D3 2000 IU/day, D3 4000 IU/day, D3 50,000 IU weekly
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, San Francisco
COVID-19 Vaccines
Improving COVID-19 Vaccine Uptake in Nursing Homes
SARS-CoV-2 vaccine, now being administered to skilled nursing facility (SNF) residents and staff, has highly variable acceptance between facilities.
- Trial name
- NCT04732819
- Testing
- High touch multi-pronged behavioral intervention
- Where
- 4 sites in United States
- Volunteers
- 23,768 people
- Sponsor
- Brown University
Physical Deconditioning
Shifting Rehabilitation Paradigms in Skilled Nursing Facilities
This study seeks to improve rehabilitation methods for restoring physical function with skilled nursing facility care. More specifically, this study is designed to evaluate the effectiveness of an intensive therapeutic…
- Trial name
- NCT02927171
- Testing
- IntenSive Therapeutic Rehabilitation for Older Skilled Nursing Home Residents
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- VA Office of Research and Development
Pressure Injury
Skin Change Actions by Nursing
Pressure injuries, local areas of damage to the skin and underlying soft tissue that are costly and painful, are often preventable with timely use of prevention strategies.
- Trial name
- SCAN (NCT06127524)
- Testing
- SEM Scanner
- Where
- 7 sites in United States
- Volunteers
- 4,733 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Long-Term Care, Long-term Care Facility
Effect of Empathy-Based Program on Nursing Assistants in Long-term Care Facilities
This randomized controlled trial aims to explore the impact of an Empathy-Based Program on the level of empathy among nursing assistants in a long-term care facility.
- Trial name
- NCT07044492
- Testing
- Virtual Reality (VR) with Debriefing
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Infection
Targeted Infection Control in Long-term Care
This is an interventional study aimed at reducing multi-drug resistance and infections in nursing home (NH) residents. Each year, a staggering 1.5-2.0 million infections occur in NHs.
- Trial name
- NCT01062841
- Testing
- Targeted Infection Control
- Where
- United States
- Volunteers
- 418 people
- Sponsor
- University of Michigan
Atrial Fibrillation, Deep Vein Thrombosis
Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.
This primary care study aims to compare the "time in therapeutic range" (TTR) of two strategies for monitoring the international normalized ratio (INR) over 6 months in nursing homes.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Stroke
- Trial name
- INR-CAP (NCT05561244)
- Testing
- Weekly monitoring using the capillary International Normalised Ratio strategy
- Where
- 33 sites in France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Covid19
COVID-19 Project ECHO in Nursing Homes
Nursing homes are ground zero for the COVID-19 pandemic. Nursing homes are ill-equipped for the pandemic; though facilities are required to have infection control staff, only 3% have taken a basic infection control course.
- Trial name
- NCT04499391
- Testing
- Project ECHO
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Alzheimer's Disease and Related Dementias
Smart Lighting for Nursing Home Residents With Dementia
This proposed study seeks to develop a smart ambient bright light (SABL) intervention to provide auto-controlled, consistent indoor lighting that incorporates natural daylight.
- Trial name
- NCT05825404
- Testing
- Smart Ambient Bright Light (SABL), Control
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Penn State University
Accidental Falls
CONNECT for Quality: A Study to Reduce Falls in Nursing Homes
Clinical trials have identified interventions that reduce adverse outcomes such as falls in nursing home (NH) residents but attempts to translate these into practice quality improvement (QI) techniques have not been successful.
- Trial name
- CONNECT (NCT00636675)
- Testing
- Falls QI, Connect
- Where
- United States
- Volunteers
- 1,726 people
- Sponsor
- Duke University
Diabetes, Hyperglycemia
Diabetes in the Elderly: Prospective Study
Diabetes is highly prevalent in the elderly, afflicting about 20% of older adults aged 65-75 years and 40% of adults >80years of age.
- Trial name
- DMElderly (NCT01131052)
- Testing
- Insulin Glargine, Insulin, Insulin glulisine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Guillermo Umpierrez
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
- Trial name
- ZEST II (NCT02589600)
- Testing
- Zoledronic acid, vitamin D, calcium
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Susan L. Greenspan