Clinical trials: Nursing Home Residents
Depression
Medication Treatment for Depression in Nursing Home Residents
This study will examine therapeutic and adverse effects of continuing versus discontinuing antidepressant medication in nursing home residents who have had no more than a single episode of depression and who no longer have…
- Trial name
- NCT00076622
- Testing
- Antidepressant medication, No antidepressant medication
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Pennsylvania
Chronic Disease, Acute Disease
Involving Nursing Home Residents and Their Families in Acute Care Transfer Decisions
This study addresses the Patient-Centered Outcomes Research Institute (PCORI) area of interest related to development of decision support tools that bring patients, families and clinicians together to decide, in this instance…
- Trial name
- NCT02568475
- Testing
- Provision of "Go to the Hospital or Stay Here?"
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Florida Atlantic University
Dementia
Music & MEmory: A Pragmatic TRial for Nursing Home Residents With ALzheimer's Disease_part1
The purpose of this trial is to test the effects of a personalized music intervention (Music and Memory, Inc.) on agitated and aggressive behaviors for nursing home residents with dementia.
- Trial name
- METRIcAL (NCT03821844)
- Testing
- Music and Memory
- Where
- 4 sites in United States
- Volunteers
- 1,073 people
- Sponsor
- Brown University
Dementia
Music & MEmory: A Pragmatic TRial for Nursing Home Residents With ALzheimer's Disease (METRIcAL)_part2
The purpose of this trial is to test the effects of a personalized music intervention (Music and Memory, Inc.) on agitated and aggressive behaviors for nursing home residents with dementia.
- Trial name
- METRIcAL (NCT04850807)
- Testing
- Music & Memory
- Where
- 4 sites in United States
- Volunteers
- 990 people
- Sponsor
- Brown University
Alzheimer's Disease and Related Dementias
Smart Lighting for Nursing Home Residents With Dementia
This proposed study seeks to develop a smart ambient bright light (SABL) intervention to provide auto-controlled, consistent indoor lighting that incorporates natural daylight.
- Trial name
- NCT05825404
- Testing
- Smart Ambient Bright Light (SABL), Control
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Penn State University
Xerosis Cutis
Skin Health and Effectiveness of Standardized Skin Care Regimens in Nursing Home Residents
Residents of institutional long-term care facilities are at high risk for developing skin and tissue diseases, e.g. xerosis cutis (including pruritus), infections (e.g., tinea pedis, candidiasis), chronic wounds or neoplastic…
- Trial name
- NCT02216526
- Testing
- Cetaphil® Restoraderm, Excipial
- Where
- Germany
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Infection
Targeted Infection Control in Long-term Care
This is an interventional study aimed at reducing multi-drug resistance and infections in nursing home (NH) residents. Each year, a staggering 1.5-2.0 million infections occur in NHs.
- Trial name
- NCT01062841
- Testing
- Targeted Infection Control
- Where
- United States
- Volunteers
- 418 people
- Sponsor
- University of Michigan
Gait, Medication Induced Gait Disturbances
BioButton Among Nursing Home Residents
This pilot study will explore the use of the BioIntellisense BioButton, a remote wearable multi-parameter monitor, to identify gait disturbances that occur as a side effect of polypharmacy.
- Trial name
- NCT06665685
- Testing
- BioButton Device, Providing Clinical Care with BioButton Device
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Charles Lin
Bacteriuria
A Trial of Cranberry Capsules for Urinary Tract Infection Prevention in Nursing Home Residents
Urinary tract infection (UTI) is the most common infection in nursing home residents, and bacteriuria is the greatest trigger for antimicrobial therapy in the nursing home setting.
- Trial name
- NCT01691430
- Testing
- 2 cranberry capsules
- Where
- 21 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes
ADA Linagliptin in Long Term Care
This is a study to determine whether glycemic control, as measured by change in HbA1c and frequency of hypoglycemia, is different between treatment with linagliptin (Tradjenta®) and basal insulin in long term care residents(LTC)…
- Trial name
- NCT02061969
- Testing
- linagliptin, insulin glargine
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Chronic Obstructive Pulmonary Disease, Depression
The Effect on Depressive Symptoms in ECF Residents With COPD
The purpose of this study is to assess the effect of treatment with Advair Diskus on depression using the Cornell depression scale in COPD patients in the nursing home.
- Trial name
- DISK-02 (NCT00974246)
- Testing
- Advair diskus
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Valley Medical Research
Pneumonia, Lower Respiratory Tract Infection
A Trial to Reduce Pneumonia in Nursing Home Residents
The purpose of this study is to test the effectiveness of an enhanced oral hygiene protocol in preventing pneumonia among nursing home residents.
- Trial name
- PRIDE (NCT00975780)
- Testing
- Enhanced Oral Care, Usual oral care
- Where
- United States
- Volunteers
- 834 people
- Sponsor
- Yale University
COVID-19, SARS-CoV2
A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff
The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease - 2019 (COVID-19).
- Trial name
- BLAZE-2 (NCT04497987)
- Testing
- Bamlanivimab, Etesevimab
- Where
- 27 sites in United States
- Volunteers
- 1,180 people
- Sponsor
- Eli Lilly and Company
Anemia, Chronic Kidney Disease
LEARN-6™: A Prospective, Observational Nursing Home Study
This is a prospective, multicenter, observational, hypothesis-generating study exploring mobility, Quality of Life and other physical performance measures among older, long-term stay Nursing Home residents with CKD, with versus…
- Trial name
- NCT00727571
- Testing
- Observations
- Volunteers
- 815 people, healthy volunteers welcome
- Sponsor
- Amgen
Diabetes, Hyperglycemia
Diabetes in the Elderly: Prospective Study
Diabetes is highly prevalent in the elderly, afflicting about 20% of older adults aged 65-75 years and 40% of adults >80years of age.
- Trial name
- DMElderly (NCT01131052)
- Testing
- Insulin Glargine, Insulin, Insulin glulisine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Guillermo Umpierrez
Alzheimer Disease
Optimizing Care for Patients With Dementia
Of the 1.4 million nursing home (NH) residents in long term care facilities, more than half have Alzheimer's disease or dementia.
- Trial name
- NCT03442322
- Testing
- transdisciplinary approach, multidisciplinary approach
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Respiratory Infection
Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents
This study will test the role of high dose vitamin D supplementation in prevention of acute respiratory infection in older nursing home residents.
- Trial name
- NCT01102374
- Testing
- High Dose Vitamin D, Standard Dose Vitamin D, Usual Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Colorado, Denver
Alzheimer's Disease and Related Dementias
OPTIMAL in NH Residents With Dementia
The purpose of this study is to develop and refine OPTIMAL and evaluate its feasibility, fidelity, and usefulness. The OPTIMAL is designed to teach staff to effectively engage residents in eating using individualized…
- Trial name
- NCT05255068
- Testing
- OPTIMAL
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Iowa
Alzheimer Disease, Dementia
Enhancing Sleep Quality for Nursing Home Residents With Dementia
This was a pilot study (R61) to prepare for a full clinical trial (R33) aiming to improve clinical outcomes for an important, growing, and vulnerable population-nursing home (NH) residents with Alzheimer's disease or related…
- Conditions
- Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
- Trial name
- 40Winks (NCT04533815)
- Testing
- LOCK sleep intervention
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Alabama, Tuscaloosa
Depressive Symptoms, Quality of Life
Life Story Book With Mentally Alert Residents of Nursing Homes
The objective of this study is to study the effects of the Life Story Book intervention on depressive symptoms and meaning in life for mentally alert residents of nursing homes.
- Trial name
- NCT03851016
- Testing
- Life Story Book, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Houston