Clinical trials: Nutrition, Enteral
Gastric Cancer, Pancreatic Cancer
The Impact of Immunostimulating Nutrition on the Outcome of Surgery
The aim of the study was to assess the clinical effect of immunostimulatory enteral and parenteral nutrition in patients undergoing resection for gastrointestinal cancer.
- Trial name
- NCT00558155
- Testing
- peptisorb, Stresson, Parenteral nutrition
- Where
- Poland
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Pancreaticoduodenectomy, Malnutrition
Enteral vs. Oral Nutrition After Pancreatoduodenectomy
Patients suffering from pancreas cancer as well as patients with chronic pancreatitis or requiring pancreas surgery often are in a compromised nutritional status.
- Conditions
- Pancreaticoduodenectomy, Malnutrition, Postoperative Complications
- Trial name
- NUTRIWHI (NCT05042882)
- Testing
- Early enteral nutrition
- Where
- 3 sites in France, Switzerland
- Volunteers
- 144 people
- Sponsor
- University of Lausanne Hospitals
Infant, Premature, Nutrition, Enteral
Aspiration of Residual Gastric Contents
The primary purpose of this study is to determine nutrition outcomes and risks to gastrointestinal integrity and function of aspirating for routine gastric contents prior to each feeding in very low birth weight premature infants.
- Trial name
- NCT01863043
- Testing
- No aspiration of gastric contents, Routine aspiration of gastric contents
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Florida
Critically Ill
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS)
This study evaluates the effect of whey protein enriched enteral nutrition in addition to exercise training on the preservation of muscle function in critically ill patients.
- Trial name
- PRESMUS (NCT03231540)
- Testing
- Whey protein supplement
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Amsterdam UMC, location VUmc
Diabetes Mellitus, Type 2
Insulin Glargine for Diabetes Metabolism(DM)Type II Patients Under Enteral Nutrition
Primary Objective: 1- Proportion of patients with mean daily glycemia <140mg/dL during the period of 7 days of treatment with glargine plus supplemental glulisine versus patients with glulisine sliding scale.
- Trial name
- NCT01081938
- Testing
- INSULIN GLARGINE, INSULIN GLULISINE
- Where
- 10 sites in Brazil
- Volunteers
- 15 people
- Sponsor
- Sanofi
Gastrointestinal Dysfunction, Critical Illness
Effect of Different Feeding Method on Gastrointestinal Function of Critical Patients
The intestine is the most vulnerable target organ in septic patients and is the first to be damaged organ in multiple organ dysfunction syndrome(MODS).Therefore, improving intestinal motility and mucosal barrier function is…
- Conditions
- Gastrointestinal Dysfunction, Critical Illness, Nutrition Disorders
- Trial name
- DFM-GFC (NCT04224883)
- Testing
- Continuously feeding, 16-hours feeding, intermittent feeding
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Tube Feeding
Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates
It is hypothesized that using methylnaltrexone in addition to pain killer narcotics (opiates) in patients will result in increased tube feeding rates with more frequent nutrition at goal calorie rate.
- Trial name
- NCT01360372
- Testing
- Methylnaltrexone, Saline injection
- Where
- 2 sites in United States
- Sponsor
- Drexel University
Sepsis
Omega-3 Fatty Acid for Critically Ill Patients.
Sepsis is the most common reason for intensive care unit (ICU) admission. Sepsis flares up the systemic inflammatory response with its mediators.
- Trial name
- NCT03388450
- Testing
- Omega 3
- Volunteers
- 110 people
- Sponsor
- Menoufia University
Severe Stroke, Enteral Nutrition
Effect of Intermittent Enteral Feeding in Severe Stroke
This is a single-center, randomized, exploratory clinical trial investigating whether intermittent enteral feeding improves outcomes compared to continuous feeding in patients with severe stroke.
- Trial name
- NCT07353658
- Testing
- Intermittent Enteral Feeding, Continuous Enteral Feeding
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Diarrhoea
The Effect of Enteral Nutrition Supplemented With Prebiotics on Colonic Microbiota in the Critically Ill Patients
Primary objective of this study is to measure the change of concentration of faecal bifidobacteria between critically ill patients who receive enteral formula with and without prebiotics during enteral nutrition.Our null…
- Trial name
- PrebioticFOS (NCT02144168)
- Testing
- Prebiotics-free enteral formula, Prebiotics containing enteral formula
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Liver Cirrhoses, Chronic Pancreatitis
Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study
Malnutrition and muscle wasting are common consequences of life-threatening, chronic diseases of the gastrointestinal tract. Such diseases include liver cirrhosis, chronic pancreatitis and short bowel syndrome.
- Conditions
- Liver Cirrhoses, Chronic Pancreatitis, Short Bowel Syndrome
- Trial name
- NCT04474743
- Testing
- No intervention - cross-sectional observational only
- Where
- 3 sites in Germany
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Enteral Nutrition
Enteral Formula Tolerance in Pediatric Patients
The purpose of this prospective study seeks to assess ability to achieve enteral feeding goals with standard polymeric enteral formula in a stable, pediatric tube-fed population.
- Trial name
- NCT02779335
- Testing
- Enteral Formula
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Société des Produits Nestlé (SPN)
Malnutrition, Gastrointestinal Cancer
Home Enteral Nutrition in Malnourished Patients With Gastrointestinal Cancer
Phase III, medical, multicentric, controlled, open label, two-parallel groups, randomized, clinical trial. The aim of this study is to evaluate the efficacy of home enteral nutrition on the nutritional status, the quality of life…
- Trial name
- NCT02664974
- Testing
- Enteral nutrition, Dietary counseling
- Where
- 2 sites in Italy
- Volunteers
- 79 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Crohn's Disease
Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission
The purpose of this study is to assess the effect of Tripterygium Glycosides Combined with enteral nutrition in the treatment of Crohn's disease for induction remission and compare the therapeutic effect with patients who only…
- Trial name
- NCT01820247
- Testing
- enteral nutrition, Tripterygium glycosides
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhu Weiming
Neurological Impairments
Nutritional Management of Neurologically Impaired Children Across China
A retrospective study to (1) investigate clinical characteristics, nutritional status, and nutritional management in neurologically impaired children in China, (2) assess whether enteral nutrition (particularly tube feeding)…
- Trial name
- NCT06612736
- Where
- China
- Volunteers
- 586 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Crohn's Disease
Cyclic Exclusive Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's Disease
The purpose of this study is to compare the rate of first relapse at 12 months between maintenance therapy with cyclic exclusive enteral nutrition (EEN) (at least 100% daily calories) and maintenance therapy with supplementary…
- Trial name
- CD-HOPE (NCT02201693)
- Testing
- MODULEN IBD
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Hospitalized Children, Nursing
Evidence-based Practice in the Management of Gastric Tube Placement in Children
This multi-center quality improvement project aims to enhance gastric tube placement practices for children by systematically reviewing the latest evidence.
- Conditions
- Hospitalized Children, Nursing, Enteral Nutrition Therapy
- Trial name
- NCT07038538
- Testing
- Evidence-based gastric placement
- Where
- 22 sites in China
- Volunteers
- 2,750 people
- Sponsor
- Children's Hospital of Fudan University
Critical Illness
The Effect of Continuous Versus Intermittent Enteral Nutrition on Metabolic Outcomes in Critically Ill Patients
The goal of this clinical trial is to investigate the effect of continuous versus intermittent enteral nutrition on metabolic outcomes in critically ill adult patients.
- Trial name
- CONVEnIENT (NCT07173504)
- Testing
- Intermittent enteral nutrition
- Where
- 5 sites in Netherlands
- Volunteers
- 124 people
- Sponsor
- Gelderse Vallei Hospital
Crohn Disease
Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial
This study will compare the tolerability and efficacy of conventional formula Exclusive Enteral Nutrition (EEN) and whole-food blended smoothie EEN by enrolling a total of 60 participants with newly diagnosed pediatric Crohn's…
- Trial name
- mRE-EEN (NCT06216899)
- Testing
- Whole-food based smoothie, Formula
- Where
- 3 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital