Clinical trials: Nutrition, open to volunteers
Malnutrition in Children, Liver Stiffness
Effect of Malnutrition on Liver and Spleen Stiffness in Children
This prospective observational study aims to evaluate the effect of malnutrition on liver and spleen stiffness in children using shear wave elastography.
- Conditions
- Malnutrition in Children, Liver Stiffness, Spleen Stiffness, Shear Wave Elastography
- Trial name
- SWE (NCT06932445)
- Testing
- Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif AĞIR
Enterocutaneous Fistulas
Vitamin C and Zinc in Patients With Enterocutaneous Fistulas.
Various micronutrients play an important role in the process of closure and recurrence of enterocutaneous fistulas, such as Vitamin C and Zinc.
- Trial name
- VITAC (NCT06009744)
- Testing
- Low-dose vitamin C and zinc, High-dose vitamin C and zinc
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Hospital Juarez de Mexico
Obesity, Overweight
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Study ASC30-301 (AURORA-1) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance doses of once-daily oral…
- Conditions
- Obesity, Overweight, Chronic Weight Management
- Trial name
- AURORA-1 (NCT07743463)
- Testing
- ASC30 tablets A1
- Where
- 122 sites in United States, Canada and 5 more
- Volunteers
- 3,003 people
- Sponsor
- Ascletis Pharma (China) Co., Limited
Prader-Willi Syndrome, PWS-like Syndrome
GROWing Up With Rare GENEtic Syndromes
Introduction Rare complex syndromes Patients with complex genetic syndromes, by definition, have combined medical problems affecting multiple organ systems, and intellectual disability is often part of the syndrome.
- Conditions
- Prader-Willi Syndrome, PWS-like Syndrome, Silver Russel Syndrome, Congenital Hypopituitarism
- Trial name
- GROW UR GENES (NCT04463316)
- Testing
- Retrospective file studies
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Obesity
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
This first-in-human study will evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending oral doses of ACCG-2671.
- Trial name
- NCT07815678
- Testing
- ACCG-2671
- Where
- 6 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
Prader-Willi Syndrome
Brain Olfactory Pathways in Prader-Willi Syndrome
Studying the cerebral activity of children with Prader-Willi Syndrom (PWS) when the study propose to them nasal activations.
- Trial name
- PRADOL (NCT07006207)
- Testing
- olfactory stimulation, functional MRI
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Cardiovascular Diseases, Obesity
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Obesity, PreDiabetes, Diabetes Type 2
- Trial name
- SWIFT-CORE-101 (NCT06412536)
- Testing
- Blood work
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brooklyn Clinical Research
Type1diabetes
Effects of Ketosis on Brain Function in Patients With T1DM
The scientific goal of this study is to examine the effects of a ketogenic diet on hypoglycemia tolerance and brain function in people with type 1 diabetes mellitus (T1D) and to clarify the mechanistic role of ketones in this…
- Trial name
- NCT04219709
- Testing
- Very low carbohydrate diet, Standard carbohydrate diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston Children's Hospital
Rhythm Nodal, Metabolism and Nutrition Disorder
The Biological Rhythm of Human Metabolite
The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs.
- Conditions
- Rhythm Nodal, Metabolism and Nutrition Disorder, Metabolism Disorder, Lipid
- Trial name
- NCT03669809
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Diet Habits, Body Composition
Body Composition and Lifestyles in Athletes With Disabilities
Disability involves limitations that affect mobility and the ability to perform daily activities and achieve competitive goals. It is expected that disability has a significant impact on body composition, including reductions in…
- Conditions
- Diet Habits, Body Composition, Athlete Assessment, Sport Nutrition
- Trial name
- PADES (NCT07464899)
- Testing
- Diet, body composition, Physical activity
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Femoral Fractures, Frailty
Preoperative Oral Nutrition And Outcomes In Frail Elderly Patients With Femur Fractures
The goal of this observational study is to learn whether preoperative oral nutrition support improves clinical outcomes in elderly patients with femur fractures who have a high frailty index.
- Conditions
- Femoral Fractures, Frailty, Malnutrition
- Trial name
- NCT07463352
- Testing
- Oral Nutritional Supplement (ONS)
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Duzce University
Gastrostomy, Tracheostomy
No DIET Trial: Dogmatic Interruption of Enteral nuTrition
There is currently limited guidance on when to hold nutritional supplementation through for patients, who are receiving tube feeding, undergoing surgical procedures.
- Trial name
- NCT06431048
- Testing
- Naso-enteral nutrition will be stopped when the patient is called to the OR for scheduled procedure., Naso-enteral nutrition will be stopped 2 hours before the scheduled procedure.
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jeffrey Coughenour
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Childhood Obesity
Leipzig Childhood Obesity Study
The aim of this study is to identify polymorphisms that make children and adolescents more prone to obesity and metabolic dysfunction, as well as to identify biomarkers that are linked to causes and consequences of obesity.
- Trial name
- NCT04491344
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Obesity, Visceral Adipose Tissue
Nutritional Oleic Acid Modulation of adIpose Cholesterol Metabolism in Patients Living With Obesity
Disruption of white adipose tissue (WAT) homeostasis during obesity is central to the development of associated cardiometabolic complications.
- Conditions
- Obesity, Visceral Adipose Tissue, White Adipose Tissue Inflammation, Subcutaneous Adipose Tissue
- Trial name
- NAMICO (NCT07027033)
- Testing
- acid-rich sunflower oil oleic acid, conventional sunflower oil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Obesity & Overweight, Culinary Medicine
Cooking Classes as a Family-based Intervention for Weight Reduction: Effects on Dietary Quality and Weight Management in Abu Dhabi (United Arab Emirates)
The goal of this quasi-experimental interventional study is to learn if healthy cooking classes for home cooks can improve weight management and dietary quality among Emirati adults with overweight or obesity living in Abu Dhabi.
- Trial name
- NCT07675148
- Testing
- Culinary Medicine Healthy Cooking and Home Meal Implementation Program
- Where
- United Arab Emirates
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institute for Healthier Living Abu Dhabi
Frailty, Malnutrition
Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)
Background. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly.
- Conditions
- Frailty, Malnutrition, Anorexia, Presbycusis
- Trial name
- EDERE 2021 (NCT04923087)
- Testing
- Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Multiple Sclerosis, Nutrition
Nutritional Status and Muscle Function in Ambulatory Multiple Sclerosis Patients With Dysphagia
The aim of this study is to evaluate the relationship between dysphagia severity and indicators of nutritional status and muscle function in ambulatory patients diagnosed with Multiple Sclerosis (MS) who have swallowing…
- Conditions
- Multiple Sclerosis, Nutrition, Swallowing
- Trial name
- NCT07564921
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Sanko University
Adolescents With Obesity, Adolescents With Overweight & Weight-related Comorbidities
A Study of Ecnoglutide Injection in Overweight or Obese Chinese Adolescents
The aim of the study is to evaluate the safety and efficacy of Ecnoglutide injection in overweight or obese Chinese adolescents
- Trial name
- NCT07836270
- Testing
- Ecnoglutide Injection
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Atrial Fibrillation (AF), Ablation Treatment
Mazdutide for Reducing Atrial Fibrillation Recurrence After Catheter Ablation in Obese Patients
This is a multicenter, open-label, superiority randomized controlled trial enrolling adult patients aged 18 to 75 years. All participants have abdominal obesity (BMI ≥ 28 kg/m² with specific waist circumference standards) and…
- Conditions
- Atrial Fibrillation (AF), Ablation Treatment, Obesity & Overweight, Mazdutide
- Trial name
- MOTIVE-AF (NCT07897305)
- Testing
- Mazdutide, Conventional treatment
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing Anzhen Hospital
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