Clinical trials: Nutrition Disorder
Obesity and Diabetes Mellitus, Type 2
A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus
The purpose of this study is to assess the effects of JNJ-64565111 compared with placebo in severely obese Type 2 Diabetes Mellitus (T2DM) participants after 12 weeks of treatment on: the percentage change in body weight from…
- Trial name
- NCT03586830
- Testing
- JNJ-64565111 Dose Level 1, JNJ-64565111 Dose Level 2, JNJ-64565111 Dose Level 3
- Where
- 27 sites in United States
- Volunteers
- 196 people
- Sponsor
- Janssen Research & Development, LLC
Malnutrition
Improving Nutritional Status With Oral Nutritional Supplement in Chinese Elderly
This is a single- country, interventional, double-arm study involving Chinese Elderly subjects.
- Trial name
- NCT02360722
- Testing
- Oral Nutritional Supplement, Nutritional Education
- Sponsor
- Abbott Nutrition
Overweight, Diabetes
Effect of Gelesis200 on Body Weight in Overweight and Obese Subjects w/o Type 2 Diabetes
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis200 on Body Weight in Overweight and Obese Subjects without or with Type 2 Diabetes
- Conditions
- Overweight, Diabetes, PreDiabetes, Obesity
- Trial name
- LIGHT-UP (NCT03058029)
- Testing
- Gelesis200
- Where
- 30 sites in United States, Canada and 6 more
- Volunteers
- 300 people
- Sponsor
- Gelesis, Inc.
Obesity, Cryotherapy Effect
Cryotherapy and Body Slimming
The purpose of this study is to evaluate the efficacy of cryotherapy on the slimming of subcutaneous fat mass in the abdomen and saddlebags.
- Conditions
- Obesity, Cryotherapy Effect, Weight Loss
- Trial name
- Cryotherapy (NCT04287153)
- Testing
- Cryotherapy on abdomen and saddlebags
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinic Cryo Esthetic
Vitamin C Deficiency, Acute Disease
A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency
The aim of this long-term observational study is the documentation of the use of PASCORBIN® 7.5 g in patients with vitamin C deficiency.
- Conditions
- Vitamin C Deficiency, Acute Disease, Chronic Disease
- Trial name
- NCT02422901
- Testing
- vitamin C
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Obesity
Effect of Shock Wave Therapy Without Biological and Immuno-histochemical Analysis.
Informative Summary: Extracorporeal shockwave therapy (ESWT) is a new method for treating aesthetic disorders within the field of aesthetic medicine, its mechanisms of action and physiological effects promise to combat localized…
- Trial name
- ESWT (NCT05017636)
- Testing
- shock wave therapy
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Indústria Brasileira Equipamentos Médicos - IBRAMED
Malnutrition
Impact of a Nutrition Quality Improvement Program on Outcomes of Malnourished Patients
A nutrition-focused QIP will be implemented as standard of care at select branches of the home health division of the health care system.
- Trial name
- NCT03011944
- Testing
- Quality Improvement Program
- Where
- 2 sites in United States
- Volunteers
- 1,546 people
- Sponsor
- Abbott Nutrition
Healthy Participants
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by mouth as different formulations.
- Trial name
- NCT07723833
- Testing
- Elecoglipron Reference Formulation Dose A, Elecoglipron Test formulation 1 Dose A, Elecoglipron Reference Formulation Dose B
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Overweight , Obesity
A Study of SRSD384 in Overweight or Obese Participants
This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD384 alone in overweight or obese participants (Part A) and in combination with tirzepatide in…
- Trial name
- NCT07557355
- Testing
- SRSD384 injection
- Where
- Australia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sirius Therapeutics Co., Ltd.
Diabete Mellitus, Hypertension
Faisalabad Initiative of Research and Management of NCDs
The burden of noncommunicable diseases (NCDs) continues to rise globally, and they have become the leading cause of morbidity and mortality, accounting for over 70% of deaths worldwide¹.
- Conditions
- Diabete Mellitus, Hypertension, Hypercholerolemia, Obesity (Disorder)
- Trial name
- FIRM-NCD (NCT07676214)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Obesity & Overweight, Gut
Precision Nutrition Recommendations Generated by Metataxonomic Microbiome Testing Improve Food Group Choices and Intestinal Health Indicators in an Obese Population in Colombia
This study evaluated whether personalized dietary recommendations based on gut microbiome testing can improve intestinal health and food choices in adults with obesity in the region of Antioquia, Colombia.
- Conditions
- Obesity & Overweight, Gut, Microbiome
- Trial name
- NCT07492485
- Testing
- Personalized dietary recommendations
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Astrolab bio
Obesity
Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.
The purpose of this study is to examine the long-term weight loss and safety of CP-945,598 in obese adults
- Trial name
- NCT00396448
- Testing
- CP-945,598 Treatment B, CP-945,598 Treatment A
- Where
- 61 sites in United States, Argentina and 9 more
- Volunteers
- 1,253 people
- Sponsor
- Pfizer
Healthy, Overweight and/or Obese Subjects
Clinical Trial to Study the Safety Tolerability, Pharmacokinetics, Food Effect & Pharmacodynamics of a New Compound P7435 in Healthy, Overweight and/or Obese Subjects
Clinical trial to study the safety tolerability, pharmacokinetics, food effect and pharmacodynamics of a new compound P7435 in in healthy, overweight and/or obese subjects
- Trial name
- NCT01764425
- Testing
- P7435
- Where
- 2 sites in India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Piramal Enterprises Limited
X-linked Hypophosphatemia
Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)
The objectives of the study are to: Identify a dose and dosing regimen of burosumab, based on safety and pharmacodynamic (PD) effect, in pediatric XLH participants Establish the safety profile of burosumab for the treatment of…
- Trial name
- NCT02163577
- Testing
- burosumab
- Where
- 9 sites in United States, France and 2 more
- Volunteers
- 52 people
- Sponsor
- Kyowa Kirin, Inc.
Obesity
Effect of Tesofensine on Weight Reduction in Patients With Obesity.
Purpose: To evaluate the efficacy on weight reduction, metabolic parameters and safety of tesofensine versus placebo in obese patients
- Trial name
- NCT00394667
- Testing
- Tesofensine
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- NeuroSearch A/S
Premenopausal Women, Overweight and Obese Women
A Pilot Study to Characterize the Bioavailability and Plasma Profile of Potato Polyphenols in Humans
Primary objective is to determine the bioavailability of and characterize the kinetic profile of target polyphenol metabolites of potatoes over 6 hour postprandial period.
- Trial name
- PPT (NCT02167607)
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Metabolic Syndrome, Diabetes
Evaluation of a Novel Self-Sampling Earwax Tool for Chronic Disease Biomarkers [TREARS STUDIES II]
Trears Biomarkers: A New Way to Manage Chronic Diseases Trears Biomarkers are changing how we care for chronic diseases by focusing on patients' needs.
- Conditions
- Metabolic Syndrome, Diabetes, Hypertension, Obesity and Obesity-related Medical Conditions
- Trial name
- Trears-II (NCT06932601)
- Volunteers
- 258 people
- Sponsor
- Trears
Metabolism and Nutrition Disorder, Obesity
A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or Obesity
This study looks at a new study medicine for weight control in people with overweight or obesity. The aim of this study is to see if the study medicine is safe for people to take.
- Trial name
- NCT03479892
- Testing
- NNC0194-0499
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Novo Nordisk A/S
Obesity, Overweight
A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity
Phase 2 clinical study will evaluate the safety, tolerability, pharmacokinetics (PK), and efficacy of various aleniglipron (GSBR-1290) dose regimens compared with placebo in participants living with obesity or overweight with ≥ 1…
- Conditions
- Obesity, Overweight, Chronic Weight Management
- Trial name
- ACCESS II (NCT06703021)
- Where
- 10 sites in United States
- Volunteers
- 85 people
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Obesity, Overweight
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Study ASC30-301 (AURORA-1) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance doses of once-daily oral…
- Conditions
- Obesity, Overweight, Chronic Weight Management
- Trial name
- AURORA-1 (NCT07743463)
- Testing
- ASC30 tablets A1
- Where
- 122 sites in United States, Canada and 5 more
- Volunteers
- 3,003 people
- Sponsor
- Ascletis Pharma (China) Co., Limited
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.