Clinical trials: Nutrition Disorder
Weight Loss, Time Restricted Feeding
TRE: Microbiome, Metabolic Health and Bone
In the Time-Restricted Eating: Microbiome and Bone (TREMBO) study, the primary goal is to determine the effect of time-restricted eating with caloric restriction compared to caloric restriction alone on bone health, as well as…
- Conditions
- Weight Loss, Time Restricted Feeding, Bone Loss
- Trial name
- TREMBO (NCT05548517)
- Testing
- Time Restricted Eating (TRE), Calorie Restriction
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Glucose Metabolism Disorders, Overweight or Obesity
Metabolic Effects of Oral Sodium Butyrate Supplementation on Overweight Individuals
Numerous evidences suggest an important role of short-chain fatty acids, produced by the intestinal fermentation of dietary fibers by the intestinal microbiota, in the modulation of various biological functions relevant to human…
- Trial name
- NCT06247020
- Testing
- Supplementation with sodium- butyrrate
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Federico II University
Cancer, Venous Thromboembolism
WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism
Cancer patients that develop blood clots are treated with low molecular weight heparin injections (LMWH). One kind of these LMWHs, dalteparin, has its dose determined based on a patient's weight using a formula of 200…
- Conditions
- Cancer, Venous Thromboembolism, Obesity
- Trial name
- WAVe (NCT03297359)
- Testing
- Dalteparin
- Where
- 5 sites in Canada
- Volunteers
- 92 people
- Sponsor
- Ottawa Hospital Research Institute
Anemia, Pregnancy
Assessing Health System Readiness for Scaling Antenatal MMS in Cambodia
Malnutrition among pregnant women in low- and middle-income countries (LMICs) can cause micronutrient deficiencies that result in adverse maternal and neonatal health outcomes.
- Conditions
- Anemia, Pregnancy, Micronutrients, Supplement
- Trial name
- TIPS-Cambodia (NCT07400796)
- Testing
- Multiple micronutrient supplement (MMS) for pregnancy
- Where
- Cambodia
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity, Overweight
Promoting Gastrointestinal Health and Reducing Subclinical Inflammation in Obese Individuals
This study evaluates the impact of increased intake of fruits and vegetables and whole grains on markers of inflammation and gut microbial composition.
- Trial name
- NCT02602496
- Testing
- Fruits and Vegetables, Whole Grain, Control
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Obesity, Childhood Obesity
The Effects of Integrative Neuromuscular Training on Physical Function in Overweight Children
Childhood obesity is an ongoing and increasing issue, resulting in changes in body mass which cause biomechanical alterations in the lower limbs.
- Trial name
- NCT05724303
- Testing
- 8-week neuromuscular training program
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Malnutrition
Malnutrition Clinical Characteristics Validation Study
Malnutrition (under-nutrition) occurs in approximately 30% of hospitalized adults worldwide and results in poor outcomes. However there is no universal method for diagnosing malnutrition.
- Trial name
- MCC (NCT02182427)
- Where
- 4 sites in United States, Australia
- Volunteers
- 54 people
- Sponsor
- Academy of Nutrition and Dietetics
NAFLD, Obesity
Biomarkers in the Diagnosis and Prognosis of NAFLD
Fibrosis is considered the leading cause of liver diseases and related mortality. Specifically, hepatic fibrosis is regarded as the consequence of reparative mechanisms initiated by hepatocytes in response to chronic damage.
- Conditions
- NAFLD, Obesity, Liver Fibrosis, Diabetes Mellitus, Type 2
- Trial name
- NCT06098417
- Testing
- Plasma Test, Liver biopsy, Visceral adipose tissue biopsy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Trieste
Obesity
Lorcaserin and Behavioral Modification for Overweight and Obesity Management in Chinese Obese Patients
The purpose of this study is to assess the safety and weight loss effect of lorcaserin at the end of the first year of treatment (Week 48) in overweight and Chinese adult obese patients compared to placebo.
- Trial name
- NCT03720574
- Testing
- Lorcaserin 10 mg BID
- Where
- 9 sites in China
- Volunteers
- 100 people
- Sponsor
- Kanion & Huawe Medicine Co.,Ltd
Pancreatic Cancer, Periampullary Cancer
Prehabilitation in Pancreatic Surgery
In patients with pancreatic cancer, older age, multiple comorbidities, frailty, malnutrition and poor functional status are common, especially in individuals receiving neoadjuvant chemotherapy.
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Frailty Syndrome, Malnutrition
- Trial name
- PIPS (NCT06069297)
- Testing
- Multimodal Prehabilitation
- Where
- Italy
- Volunteers
- 238 people
- Sponsor
- IRCCS San Raffaele
Prediabetic State, PreDiabetes
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
The purpose of the study is to assess the feasibility and acceptability of incorporating hands-on nutritional demonstrations to enhance the Diabetes Prevention Program (DPP) curriculum among patients who are at-risk for…
- Conditions
- Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy
- Trial name
- NCT06897982
- Testing
- One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Insulin Resistance, Hyperglycemia
A Cold Physical Treatment to Manage Insulin Resistance
Insulin resistant volunteers will choose to undergo an 8-week cold treatment, 2 hours per day, to selective regions of the body enriched with brown fat including neck, supraclavicular and interscapular regions) in combination…
- Conditions
- Insulin Resistance, Hyperglycemia, Hyperinsulinemia, Diabetes
- Trial name
- CTPMIR (NCT02852759)
- Testing
- Selective Cold, Electroacupuncture
- Where
- China
- Volunteers
- 33 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Obesity, Morbid
Preoperative Carbohydrate Loading in Bariatric Surgery
The aim of this study is to perform a randomized non-blinded clinical trial to assess influence of preoperative carbohydrates loading in patients undergoing bariatric surgery measured by changes in the course of the postoperative…
- Trial name
- NCT04486079
- Testing
- Nutricia PreOp
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Medical University of Gdansk
Pediatric Obesity
Evaluation of Body Composition in Pediatric Patients With Overweight or Obesity
In recent decades, the prevalence of obesity and overweight has dramatically increased globally, representing a serious problem for society and for the health system of many countries, estimating an impact of 2-8% on global…
- Trial name
- OBIASITY (NCT06312280)
- Testing
- Mediterranean diet
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity and Overweight
Plant-Based Foods and (Poly)Phenol Supplementation in Gut Microbiota Modulation, Body Weight, and Cardiometabolic Risk
This single-blind, randomized controlled trial aims to evaluate the effects of increased dietary polyphenol intake-either through a healthy plant-based diet (PBD) or supplementation-on body weight and cardiometabolic risk factors…
- Trial name
- PREDIET-ARAC (NCT06911346)
- Testing
- Diet supplementation, Polyphenol-rich supplement
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Universidad Catolica de Temuco
Alzheimer Disease(AD), Sarcopenia
Silkworm Pupa Powder Improves Dementia.
The purpose of this clinical trial is to determine whether silkworm pupa powder is effective in treating Alzheimer's disease. It will also investigate whether silkworm pupa powder can improve the nutritional and frailty status of…
- Conditions
- Alzheimer Disease(AD), Sarcopenia, Asthenia
- Trial name
- NCT06898476
- Testing
- Silkworm pupa powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Critically Ill
Protein Supplementation vs Standard Feeds in Underweight Critically Ill Children: A Dual-Centre Pilot RCT
This pilot trial is part of a long-term research program leading to a large trial to determine if a strategy of supplementing protein in a subset of critically ill children is superior to standard enteral nutrition care.
- Trial name
- NCT04565613
- Testing
- Enteral protein supplementation
- Where
- Singapore
- Volunteers
- 34 people
- Sponsor
- KK Women's and Children's Hospital
Overweight and Obese Women
The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
The study will be a randomized, double-blind, 17-day metabolic intervention trial including 14 days of high-dose or low-dose iron supplementation. A total of 70 overweight or obese (OW/OB) women will be enrolled.
- Trial name
- NCT07315282
- Testing
- 195 mg iron daily, 15 mg iron daily
- Where
- Lebanon
- Volunteers
- 70 people
- Sponsor
- Nicole Stoffel
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