Clinical trials: Nutrition Disorder
Obesity & Overweight, Healthy Adult
Vitis Intervention Trial in Substrate Metabolism
Obesity is associated with reduced metabolic flexibility (MetFlex), the capacity to shift between carbohydrate and lipid oxidation in response to nutrient availability.
- Trial name
- VITIS (NCT07800988)
- Testing
- Freeze-Dried Whole Grape Powder
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Diabetes
Crossover Trials Which Assessed Consumption of Slowly Digestible Carbohydrates for 21 Days on Gastric Emptying Rates
To gain a better understanding about the conditioning effect of consumption of slowly digestible carbohydrate on gastric emptying rate, respiratory quotient and metabolic flexibility, this study will focus on monitoring change in…
- Trial name
- INT (NCT05430061)
- Testing
- slowly digestible carbohydrate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Purdue University
Morbid Obesity, Opioid-Related Disorders
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of…
- Conditions
- Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
- Trial name
- NCT03925610
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Obesity
To Study Different Levels of MK0493 for Safety, Efficacy, and Tolerability in Obese Patients (0493-017)(COMPLETED)
To study different doses of MK0493 for safety, efficacy and tolerability in obese patients.
- Trial name
- NCT00482196
- Testing
- MK0493
- Volunteers
- 173 people
- Sponsor
- Merck Sharp & Dohme LLC
Cardiovascular Diseases, Heart Diseases
Genomic Dissection of a QTL Affecting the Lipid Profile
To search for the genetic cause of the metabolic syndrome, a lipid disorder that poses a major risk for coronary heart disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia, Familial Combined
- Trial name
- NCT00064688
- Sponsor
- Medical College of Wisconsin
Obesity, Insulin Resistance
Neural Functioning of Feeding Centers in Obese Youth
To explore whether obese adolescents with insulin resistance and relative low leptin levels exhibit functional alterations of the neuronal circuits involved in the regulation of energy metabolism and food seeking behaviors.
- Trial name
- NCT01808846
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yale University
No Condition
NutFinForce - Lifestyle Performance Medicine Intervention on Defense Performance in Finland
Summaries are in Finnish for attendees are availabe and reviewed in ethical approcval process
- Trial name
- NutFinForce (NCT06799988)
- Testing
- Digitally Delivered Lifestyle Performance Medicine intervention
- Where
- Finland
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Scheduled Cardiac Surgery, Sternotomy
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters
Postoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and…
- Conditions
- Scheduled Cardiac Surgery, Sternotomy, Elderly Patients, Obesity
- Trial name
- BLS-Sterno (NCT01828788)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Overweight, Postmenopausal
Post Exercise Substrate Oxidation, Appetite and Energy Intakes in Overweight/Obese Postmenopausal Women (EScAPE)
High-intensity interval exercise (HIIT), as compared to moderate intensity continuous training (MICT), is a time-efficient strategy to decrease total and abdominal fat mass (FM).
- Trial name
- EScAPE (NCT04364061)
- Testing
- Moderate Intensity Continuous Exercise, High-Intensity Interval Exercise (1), High-Intensity Interval Exercise (2)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Obesity
Identification of In-vivo Probe Based Confocal Laser Endomicroscopy Cellular Characteristics in Obese Women
Previous studies have shown that histological changes in the gastric mucosa between obese and non-obese individuals do exist. Understanding these histological differences (between obese and non-obese individuals) might elucidate…
- Trial name
- NCT02781961
- Testing
- cellvizio
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Obese, Overweight
The Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight Patients
This is a multicenter, randomized, double-blind, placebo controlled trial to evaluate the effect and safety of Liraglutide Injection on body weight loss compared with placebo in obese or overweight adult patients with comorbidity…
- Trial name
- NCT04605861
- Testing
- Liraglutide
- Where
- China
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Obesity, Overweight
Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults
The purpose of this micro-randomized trial is to evaluate the effects of 7 types of intervention messages targeting specific behavior change techniques (i.e., BCT messages) delivered in "just-in-time" (JIT) moments on daily…
- Conditions
- Obesity, Overweight, Overweight and Obesity
- Trial name
- Nudge (NCT05625061)
- Testing
- Core Behavioral Weight Loss (BWL) Intervention, Behavior Change Technique 1 Message (Action Planning), Behavior Change Technique 2 Message (Discrepancy between Current Behavior and Goal)
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of North Carolina, Chapel Hill
Metabolic Syndrome, Insulin Resistance
Impact of Obstructive Sleep Apnea Syndrome on Metabolic Syndrome in Severe Obesity
The aim of this project is to study the relationship between obstructive sleep apnea (OSA) and metabolic syndrome (MS) in a population of obese patients who are candidates for bariatric surgery.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Adipokines, Cytokines
- Trial name
- SYBILA (NCT01029561)
- Testing
- CPAP, Diet
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Hospital Universitari de Bellvitge
Overweight, Obesity
Effect of Dietary Habits on Metabolic Health
The goal of this application is to understand the connection between people's eating habits and the risk for developing diabetes, obesity, and cardiovascular disease.
- Conditions
- Overweight, Obesity, Prediabetes, Meals
- Trial name
- NCT02298790
- Testing
- Meal schedule
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity
Varying the Energy Density and Portion Size of the Main Course After a First-course Salad
The purpose of this research is to determine whether varying the energy density and portion size of the main course will affect meal energy intake after consumption of a first course that has previously been shown to enhance…
- Trial name
- NCT01729390
- Testing
- Energy density and portion size feeding study
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Penn State University
Down Syndrome
Nutritional Status in Children With Down Syndrome
To evaluate the nutritional status of children with Down's syndrome and to determine the prevalence of nutritional deficiencies among those children.
- Trial name
- DS (NCT06989060)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Lung Cancer (NSCLC)
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
The general goal of the STARLighT study is to test whether a structured physical exercise and nutritional intervention significantly impacts clinical outcomes in patients with early-stage lung cancer.
- Trial name
- STARLighT (NCT07042724)
- Testing
- Physical exercise and nutrition intervention for the neoadjuvant setting, Physical exercise and nutrition for the adjuvant setting, Health educational material
- Where
- Italy
- Volunteers
- 324 people
- Sponsor
- Universita di Verona
Vitamin D Deficiency, Parkinson Disease
12 Weeks Vitamin D Supplementation and Physical Activity in PD Patients With DBS
Parkinson's disease (PD) is the second most frequently appearing neurodegenerative disease. It is a progressive disease of the central nervous system (CNS) and affects around 1% of people over 60 years old.
- Trial name
- NCT04768023
- Testing
- Juvit D3
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Obesity
Healthy Sleeping and Feeding During Infancy
Childhood obesity has reached epidemic proportions and its prevalence continues to rise, even among very young children. A recent report from the National Health and Nutrition Examination Survey (NHANES) revealed that from 1999…
- Trial name
- NCT00125580
- Testing
- Infant sleep instruction
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pregnancy, Malnutrition in Pregnancy
Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)
Acute malnutrition in pregnancy is a risk factor for adverse outcomes in mothers and their unborn children. Undernutrition during pregnancy can result in maternal complications such as life-threatening hemorrhage and hypertensive…
- Conditions
- Pregnancy, Malnutrition in Pregnancy, Nutrition Disorders, Stunting
- Trial name
- NCT03079388
- Testing
- Ready-to-use-supplementary food, Corn-soy-blend, Monthly intermittent preventive treatment of malaria during pregnancy (IPTp)
- Where
- Sierra Leone
- Volunteers
- 1,489 people
- Sponsor
- Washington University School of Medicine
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