Clinical trials: Nutrition Processes
Short Bowel Syndrome, Intestinal Failure
Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants?
The aim of this study is to determine the feasibility of conducting a trial to examine the efficacy of an ω3FA (Omega-3 fatty acid) containing balanced lipid emulsion in the prevention of progression of PNALD in infants with…
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Gastrointestinal Motility Disorder, Mucosal Enteropathy
- Trial name
- NCT00793195
- Testing
- Intralipid 20%, SMOFlipid 20%
- Where
- 5 sites in Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
End-Stage Liver Disease, Liver Transplantation
Multidimensional Frailty Assessment and Post-Transplant Outcomes in Liver Transplant Candidates
This study will evaluate frailty, nutrition, sarcopenia, and psychological health in people waiting for a liver transplant. The purpose is to understand how these factors affect outcomes before and after transplantation.
- Conditions
- End-Stage Liver Disease, Liver Transplantation, Cirrhosis
- Trial name
- NCT07414095
- Testing
- Comprehensive Observational Assessment in Liver Transplant Candidates
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Diabetes Mellitus, Type 1
TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk
The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) is an international effort to conduct a primary prevention nutrition trial for type 1 (insulin-dependent) diabetes.
- Trial name
- TRIGR (NCT00179777)
- Testing
- Hydrolysed infant formula, Nonhydrolysed infant formula
- Where
- 18 sites in United States, Australia and 13 more
- Volunteers
- 5,156 people
- Sponsor
- University of Helsinki
Morbid Obesity
Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, and Activation of Central Reward System
Background: The investigators have found that obesity and insulin resistance result in significantly increased brain insulin-stimulated glucose uptake, whereas in every other tissue glucose uptake is lower in the obese compared…
- Trial name
- BARIBRAIN (NCT04343469)
- Testing
- Bariatric Surgery (RYGB or LSG)
- Where
- 2 sites in Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Chronic Pancreatitis
The Diagnosis of Chronic Pancreatitis
To develop a new standardized multimodal diagnostic approach to CP considering: WP 1: Fat in faeces and functional testing; the combination of tests has to be easy to practice, should take as little time as possible and…
- Trial name
- NCT01059669
- Testing
- diagnostic test
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Nutrition Poor
Decision-Making Processes While Online Grocery Shopping
Individuals living with food insecurity are disproportionately affected by overweight and obesity and associated chronic health problems.
- Trial name
- NCT03248583
- Testing
- Default option, Psychoeducation, Incentive
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University at Albany
Post Operative Nausea and Vomiting, Sleeve Gastrectomy
Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy
The aim of this study is to compare the possible efficacy of ondansetron and gabapentin on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.
- Conditions
- Post Operative Nausea and Vomiting, Sleeve Gastrectomy, Morbid Obesity
- Trial name
- NCT05620641
- Testing
- Ondansetron 8mg, Gabapentin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Obesity, Metabolic Diseases
Fibrosis a New Pathological Actor in Adipose Tissue
Adipose tissue (AT) has specific alterations in obesity in particular increased fibrosis amount compared to lean subjects. Fibrosis amount measured by immunohistochemistry on adipose biopsies appears to to predict weight loss…
- Conditions
- Obesity, Metabolic Diseases, Fibrosis, Body Weight
- Trial name
- fibrota (NCT01655017)
- Testing
- biopsy
- Where
- 2 sites in France
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Neoplasms
Fish Oil Supplement in Rectal Cancer
Neoadjuvant treatment with radiotherapy (RDT) and chemotherapy (CT) are the treatment of choice for rectal adenocarcinomas in stages II and III. This results currently in pathologic complete response in 10% to 30% of cases.
- Trial name
- NCT02534389
- Testing
- omega-3 fish oil
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- AC Camargo Cancer Center
Surgical Wound Infection, Infection; Cesarean Section
Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section
The purpose of this study is to examine whether obese women (BMI >= 30) who give birth by caesarean section have a reduced incidence of wound infection and dehiscence when incisional Negative Pressure Wound Therapy is applied…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- NCT01890720
- Testing
- iNPWT, Standard postoperative wound dressing
- Where
- 5 sites in Denmark
- Volunteers
- 876 people
- Sponsor
- Odense University Hospital
Chronic Hepatitis C
Vitamin D Deficiency in Subjects With Chronic Hepatitis C Compared to Healthy Volunteers
The objective of this study is to assess the prevalence of vitamin D deficiency in patients with chronic Hepatitis C compared to a matched control group of healthy individuals in the Sioux Falls area.
- Trial name
- NCT01274013
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Child Malnutrition
Addressing the Double Burden of Malnutrition in Guatemala
Globally, populations are experiencing increases in the double burden of malnutrition, commonly defined as maternal overweight/obesity and child stunting in the same household.
- Trial name
- NCT06750120
- Testing
- Family food ration, Optimal weight counseling, Enhanced Usual Care
- Where
- Guatemala
- Volunteers
- 1,532 people
- Sponsor
- Brigham and Women's Hospital
Diabetes, Obesity
A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling
The purpose of this study is to determine whether a lipid infusion can up-regulate toll-like receptor 4 (TLR4) signaling in human subjects
- Trial name
- NCT01740817
- Testing
- Intralipid 20%, Saline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Liver Failure, Critical Illness
Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure
The purpose of the study is to determine the tolerance on lipid metabolism and the safety of short-term parenteral nutrition as compared to enteral nutrition in critically ill patients with liver failure.
- Trial name
- SELLIFA (NCT00522730)
- Testing
- Parenteral nutrition, Enteral nutrition
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Short Bowel Syndrome
Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short Bowel Syndrome Pediatric Patients
The purpose of this study is to evaluate if the treatment could maximize intestinal absorption, minimize the inconvenience of diarrhea, and avoid, reduce or eliminate the need for parenteral support (PS) to achieve normal growth…
- Trial name
- REVE (NCT03562130)
- Testing
- Teduglutide
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stunting
Impact of Life-size Growth Charts on Understanding of Stunting
Randomized control trial testing whether exposure to a wall hanging (growth mat) enabling parents to physically compare their children's height against the World Health Organization (WHO) standards for height-for-age in…
- Trial name
- NCT04579328
- Testing
- Exposure to Growth Mats
- Where
- United States
- Volunteers
- 1,019 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dehydrated, Water-Electrolyte Imbalance, Malnutrition
Explorative Study on a New Device' Ability to Register Hydration Change in Elderly Subjects During Rehabilitation.
Test the ability of continuous measurements from a new sensor patch to set the hydration state in subjects who are malnourished/dehydrated or overhydrated or otherwise not optimally hydrated.
- Trial name
- NCT04937465
- Testing
- No intervention done
- Where
- 6 sites in Norway
- Sponsor
- Mode Sensors AS
Obesity, Overweight
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities
The main purpose of this phase 3b study is to evaluate the efficacy and safety of tirzepatide compared with semaglutide in adult participants who have obesity or overweight with weight related comorbidities without Type 2…
- Trial name
- SURMOUNT-5 (NCT05822830)
- Testing
- Tirzepatide, Semaglutide
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 751 people
- Sponsor
- Eli Lilly and Company
Primary Neoplasm, Secondary Neoplasm
Nutritional Supplementation in Patients With no Signs of Malnutrition
The aim of the study was to assess the effect of nutritional supplementation on nutritional status and postoperational complications in cancer patients with no clinical signs of malnutrition
- Conditions
- Primary Neoplasm, Secondary Neoplasm, Abdominal Neoplasm
- Trial name
- NCT01894828
- Testing
- Nutritional supplements
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- MedSource Polska
Malnutrition, Child, Growth; Stunting, Nutritional
Samaki Salama: Small-scale Fisheries for Healthy Nutrition and Ecosystems
The purpose of this study is to test the effectiveness of a bundled intervention to address malnutrition and its intersections with nutrition security and fisheries sustainability in Kilifi, Kenya.
- Trial name
- NCT05254444
- Testing
- Social marketing, social marketing + gear modification
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
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