Clinical trials: Nutrition Processes
Cardiometabolic Risk, Abdominal Obesity
Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention
The aim of the study is to evaluate the synergistic effects of daily consumption of food products fortified with bioactive components (fibres, polyphenols, omega-3, Slow Digestible Starch) for 9 weeks, compared to the daily…
- Trial name
- SINFONI (NCT04190706)
- Testing
- bioactive components fortified food products intake (biscuits and cookies), control food products intake (biscuits and cookies)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Chronic Disease
Multiple Chronic Conditions for Older Adults
Multiple chronic conditions are common and expensive among patients aged ≥65 and are associated with lower quality of life, poorer response to treatment, worse medical and psychiatric outcomes, higher mortality, and higher costs…
- Trial name
- NCT03387735
- Testing
- Treatment as usual (TAU) + Internet, TAU + ElderTree
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Critical Illness, ICU
Trial on the Impact of Indirect Calorimetry-Guided Nutritional Support on Patient-Centered Outcomes in Critically Ill Patients - The OPTICal Study
This multicentric randomized controlled trial aims to evaluate whether indirect calorimetry (IC)-guided nutritional support improves patient-centered outcomes in critically ill adult patients compared to standard formula-based…
- Trial name
- OPTICal (NCT07343440)
- Testing
- Indirect Calorimetry Group, Control Group - Formula-Based Group
- Where
- 3 sites in Switzerland
- Volunteers
- 356 people
- Sponsor
- HEIDEGGER CP
Obesity
Clinical Efficacy and Safety of a Laparoscopic Sleeve Gastrectomy in Obese Patients
This study aim to evaluate the clinical efficacy and safety after laparoscopic sleeve gastrectomy in patients with obesity. 300 patients with obesity and 49 healthy individuals with normal BMI were enrolled.
- Trial name
- NCT04548232
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Docosohexaenoic Acid Supplementation of Mothers to
DHA Supplementation for Lactating Mothers
The purpose of this research study is to find out whether preterm infants are receiving enough of the essential and long chain fatty acids important for brain development and immune function.
- Trial name
- DHA-1 (NCT01732874)
- Testing
- Expecta 200 mg, Expecta 1 gram
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Chronic Kidney Disease, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients
The investigators hypothesize that the chronic kidney disease patients who suffer from vitamin D deficiency will be benefit from given Vitamin D2 because coronary artery calcification and hyperparathyroidism will be improved.
- Trial name
- EVIDENCE (NCT01672047)
- Testing
- Vitamin D2
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Peking University People's Hospital
Obesity, Inflammation
Walnut Consumption and Gut Microbiota
Obesity is a growing health issue that effects the majority of adults in the United States. Prevalence of other metabolic diseases are increased in obese adults, including systemic inflammation.
- Trial name
- NCT05441748
- Testing
- Walnuts, Walnut Oil, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Dehydration
Reference Values and Determinants of Hydration in Children 3-13 y
Purpose: 1. Develop reference values for hydration biomarkers for children of 3 to 13 years old 2. Explore the association between children's and parents' hydration markers and fluid intake habits in children aged 3-13 y 3.
- Trial name
- HYBISKUS (NCT02937038)
- Where
- United States
- Volunteers
- 1,454 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Infective Endocarditis, Endocarditis, Bacterial
Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment
Infective endocarditis (IE) is associated with high morbidity and mortality. Patients with IE are affected by a lengthy hospitalization, leading to physical deconditioning and a rapid decline in physical fitness, muscle mass and…
- Conditions
- Infective Endocarditis, Endocarditis, Bacterial, Infection; Heart, Bacteremia
- Trial name
- ENDOCARE (NCT06563609)
- Testing
- Intensive physical Therapy, Probiotic treatment, Individualised Nutritional Support
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Johannes Grand
Malnutrition, Pneumonia
Childhood Acute Illness and Nutrition Network
The CHAIN Network aims to identify modifiable biomedical and social factors driving the greatly increased risk of mortality among young undernourished children admitted to hospital with acute illness, as inpatients and after…
- Conditions
- Malnutrition, Pneumonia, Diarrhea, Sepsis
- Trial name
- CHAIN (NCT03208725)
- Where
- 8 sites in Bangladesh, Kenya and 3 more
- Volunteers
- 4,335 people
- Sponsor
- University of Oxford
Growth Failure, Stunting
ELICIT 2.0: Pilot Study of the Effect of Maternal Protein Supplementation During Lactation on Childhood Growth
Haydom Global Health Research Center in north central Tanzania represents an important rural setting for performing high-quality medical research in sub-Saharan Africa.
- Conditions
- Growth Failure, Stunting, Malnutrition, Protein Malnutrition
- Trial name
- NCT04565314
- Testing
- Plumpy'Mum
- Where
- Tanzania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Critical Illness, Enteral Nutrition
Trial of Enteral Glutamine on Intestinal Permeability in Critically Ill Patients
Glutamine-induced recovery in intestinal barrier function by reducing bacterial translocation was demonstrated in previous studies.
- Conditions
- Critical Illness, Enteral Nutrition, Intestinal Permeability
- Trial name
- NCT03113240
- Testing
- Glutamin, Maltodextrin
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University
Chronic Kidney Hospitalized
Wasting in Chronic Kidney Disease
Protein energy wasting is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of…
- Trial name
- PEW (NCT03135717)
- Testing
- Nutritional care
- Volunteers
- 48 people
- Sponsor
- Hospices Civils de Lyon
ICU Patients
Scandinavian Intensive Care Unit (ICU) Glutamine Study
This is a prospective double-blinded placebo-controlled block randomized study in intensive care patients comparing intravenous glutamine supplementation to placebo. The hypothesis is an improvement of clinical outcome.
- Trial name
- NCT00922714
- Testing
- Glutamine
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Scandinavian Critical Care Trials Group
Obesity, Diet Modification
The Effects of Lowering Dietary Carbohydrates on Health, Exercise Performance and Wellbeing-related Outcomes
The aim of the study is to investigate the long-term effects of the ketogenic diet and exercise (including interactions) on health markers, exercise performance and wellbeing outcomes in sedentary overweight individuals.
- Trial name
- NCT03934476
- Testing
- Ketogenic diet, Exercise HIIT
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University of Ostrava
Anemia, Chronic Liver Disease
Etiopathogenesis of Anemia in Chronic Liver Disease
Anemia is the most common complication of liver cirrhosis and is seen in 75% of cases. The etiology of anemia in liver disease is diverse and often multi-factorial.
- Trial name
- NCT04622449
- Where
- India
- Volunteers
- 125 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
COPD
Sarcopenia in COPD Patients: a French Study
The prevalence of sarcopenia is high in many organ pathologies such as COPD, but remains little studied in acute respiratory failure.
- Trial name
- SARCOBS (NCT03111849)
- Testing
- sarcopenia
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Clermont-Ferrand
Morbid Obesity, Postoperative Pain
Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery
This prospective randomized controlled trial aims to compare the clinical effectiveness and safety of opioid-free anesthesia (OFA) versus traditional opioid-based anesthesia (OBA) in adult patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Postoperative Pain, Opioid Free Anesthesia, Bariatric Surgery
- Trial name
- NCT07337135
- Testing
- Opioid-Based Anesthesia (Remifentanil-Based Protocol), Opioid-Free Anesthesia (Dexmedetomidine-Ketamine-Lidocaine Protocol)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Hospital dos Lusíadas
Pregnancy, Malaria
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
There are few safe, effective, and affordable interventions to improve pregnancy outcomes in low resource settings where the highest rates of poor birth outcomes occur.
- Conditions
- Pregnancy, Malaria, Nutrition, Placental Development
- Trial name
- AGREE (NCT05934318)
- Testing
- L-citrulline
- Where
- Kenya
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
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