Clinical trials: Nutrition Sciences
Obesity
Impact of Black Pepper on Energy Expenditure and Substrate Utilization
As obesity rates worldwide continue to increase, there is a focus on identifying active food ingredients which increase metabolic rate which can be used as a dietary supplement in the treatment of overweight and obesity.
- Trial name
- NCT01729143
- Testing
- 24-hour energy expenditure and substrate utilization
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Liver Disease Parenchymal
Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery
Obesity is a chronic disease characterized phenotypically by an increase in body weight (BMI>30 kg/m2) and by a series of associated pathologies, such as hypertension, diabetes, hepatic steatosis.
- Trial name
- NCT06372015
- Testing
- Nutritional Approach, Surgery Approach
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Ulcerative Colitis
Fecal Transplantation Using a Diet for Donor and Recipient in Refractory Colitis
Changing the microbiota has become the most intriguing target for intervention in inflammatory bowel disease (IBD). Dietary therapy is successful in mild to moderate Crohn's disease and may be effective in mild to moderate…
- Trial name
- NCT02734589
- Testing
- Fecal transplantation, Unique novel Diet for UC and Unique novel Diet for the donor + FMT, Unique novel Diet for UC
- Where
- 5 sites in France, Israel and 1 more
- Volunteers
- 54 people
- Sponsor
- Wolfson Medical Center
Obesity
Impact of Fitbit Plus Weight Management Program on Physical Activity and Metabolic Disease in Obese Adolescents
This study is evaluating the feasibility and efficacy of using Fitbit Charge HR devices to remotely track the physical activity of obese pediatric patients who are concurrently enrolled in a comprehensive weight loss intervention…
- Trial name
- NCT02507791
- Testing
- Fitbit Charge HR plus weekly phone calls to review physical activity data
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University Hospitals Cleveland Medical Center
Enteral Nutrition, COVID-19 Acute Respiratory Distress Syndrome
Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19
The goal of this observational study is to determine the relationship between the nutritional profile of critically ill patients diagnosed with COVID-19 and disease severity, prognosis, and survival, to assess the ability to meet…
- Trial name
- NCT06134674
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara City Hospital Bilkent
Childhood Obesity, Self-regulation
ONE PATH: Optimizing Nutrition Education for Parents and Teachers for Healthy Growth
This proposal uses an innovative methodological framework, the multiphase optimization strategy (MOST), to design an effective and efficient responsive feeding (RF) intervention that promotes child appetite self-regulation among…
- Conditions
- Childhood Obesity, Self-regulation, Appetite Regulation
- Trial name
- ONE PATH (NCT03817021)
- Testing
- ECE Provider, Parent Intervention, Child intervention
- Where
- United States
- Volunteers
- 1,461 people, healthy volunteers welcome
- Sponsor
- Penn State University
Malnutrition
Different Strategies for Preventing Severe Acute Malnutrition in Niger
Options for large-scale preventive distributions include fortified blended flours, ready-to-use foods and direct cash transfer either alone or in combination with family protective rations.
- Trial name
- NCT01828814
- Where
- Niger
- Volunteers
- 7,836 people, healthy volunteers welcome
- Sponsor
- Epicentre
Obesity
Effect of Specific Diet and Physical Activity on Weight and/or Fat Loss
The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low…
- Trial name
- NCT02325804
- Testing
- Lifestyle Counseling
- Where
- Slovakia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Obesity, Metabolic Syndrome
Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss
Dyspnea is a common complaint in obese patients. The mechanisms behind this dyspnea and the effects of weight loss on dyspnea are not completely understood.
- Trial name
- NCT03035149
- Testing
- Weight Management Program
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Transsexualism, Transgenderism
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Current study aims to characterize five highly interconnected physiological systems in patients undergoing cross-sex hormone therapy - namely glucose and lipid metabolism, energy balance, eating behavior, functional brain…
- Conditions
- Transsexualism, Transgenderism, Adiposity, Eating Behavior
- Trial name
- HHS (NCT04838249)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Diet, Healthy, Eating Behavior
SEP and the Impact of Portion Size on Daily Energy Intake
Reducing food portion size is a potential strategy to reduce energy intake. There is some evidence to suggest that individuals with lower socioeconomic position (SEP) intend to eat more from larger portions, suggesting that the…
- Conditions
- Diet, Healthy, Eating Behavior, Obesity
- Trial name
- NCT05173376
- Testing
- Portion size manipulation
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Inflammatory Bowel Diseases
Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing elective or emergent resection surgery for inflammatory bowel disease…
- Trial name
- NCT06309017
- Testing
- Nutrition specialist, Ensure Surgery Immunonutrition shakes
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Insulin Sensitivity, Obesity
Comparative the Effect of Metformin and Acupuncture on Weight Loss and Insulin Sensitivity
The investigators designed this randomized double blind (patients/ assessor) clinical trial to compare the therapeutic effects of Metformin monotherapy with Metformin and acupuncture combined therapy on weight loss and insulin…
- Trial name
- NCT02438540
- Testing
- metformin, acupuncture
- Volunteers
- 43 people
- Sponsor
- Amir Firouzjaei
Crohn Disease, Nutrition Assessment
Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients
Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is on the rise globally. Although medical treatments have advanced, CD still leads to significant health issues due to disease progression and medication side…
- Conditions
- Crohn Disease, Nutrition Assessment, Diet Therapy
- Trial name
- CONSISTENT (NCT06953791)
- Testing
- aCDED + Modulen, Prednisolone
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University Hospital Tuebingen
Bacterial Overgrowth Syndrome Small Bowel, Heart Failure with Preserved Ejection Fraction
Rifaximin and Cardiac Function in Patients with Heart Failure with Preserved Ejection Fraction
Single-center, double-blind, randomized, controlled intervention study of the effect of correction of bacterial overgrowth syndrome in the small intestine (SIBO) on cardiac function in patients with heart failure with preserved…
- Trial name
- SIBO-HFpEF (NCT06652087)
- Testing
- Rifaximin, Standard HFpEF treatment
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Type 2 Diabetes, Insulin Resistance
Effect of Low-Glycemic Index Mediterranean Diet on AGEs
Advanced glycation end products (AGE) result from a chemical reaction between the carbonyl group of reducing sugar and the nucleophilic NH2 of a free amino acid or a protein; lysine and arginine being the main reactive amino…
- Conditions
- Type 2 Diabetes, Insulin Resistance, Obesity, Cardiovascular Disease
- Trial name
- Nutri_AGEs (NCT02353416)
- Testing
- Low Glycemic Index Mediterranean Diet, INRAM Guidelines' diet
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Sleep Restriction
Nutrition Intervention to Promote Immune Recovery From Sleep Restriction
Physical and psychological stress on Warfighters during training and operational missions can suppress immune responsiveness. Skin wound models can be used to detect changes in immune function.
- Trial name
- NCT03525184
- Testing
- Additional protein and multi-nutrient beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity and Overweight, Diabetes Mellitus
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults.
- Conditions
- Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
- Trial name
- FAM WEL B-ing (NCT06724406)
- Testing
- Family Skills Training Session Quantity: 5, Family Skills Training Session Mode: In-person, Family Skills Training Content: Communication
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of North Carolina, Chapel Hill
Barrett's Esophagus, Obesity
Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids
This study is being done to understand the effect of dietary omega-3 fats in decreasing tissue inflammation in Barrett's esophagus.
- Trial name
- NCT01733147
- Testing
- Omega-3 polyunsaturated fatty acids
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
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