Clinical trials: Nutrition Sciences
Type 2 Diabetes, Obesity
Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 Diabetes
The study seeks to explore the cardiovascular effects of co-agonism at the glucagon and (glucagon-like peptide-1) GLP-1 receptor. Glucagon and exenatide will be intravenously infused into participants with type 2 diabetes (T2DM).
- Trial name
- COCONUT (NCT04307797)
- Testing
- 0.9% Sodium-chloride, Exenatide (50ng/min for 30 minutes loading followed by 25ng/min maintenance) and glucagon 12.5ng/kg/min, Glucagon 12.5ng/kg/min and 0.9% saline
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Childhood Obesity, Family
FamCe-HLP- Family-centered Obesity Management Program in Primary Care Settings
This clinical trial aims to compare the adiposity and weight status among mother-child dyads with overweight or obesity who receive the Fam-Ce-HLP intervention with the mother-child dyads with overweight or obesity who did not…
- Conditions
- Childhood Obesity, Family, Behavior, Health, Lifestyle, Healthy
- Trial name
- NCT06394882
- Testing
- Family-Centered Healthy Lifestyle Program (FamCe-HLP)
- Where
- 4 sites in Oman
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oman Ministry of Health
Obesity, Taste Sensitivity
Genetics and Fat Taste Sensitivity
A cross-sectional quantitative study will be carried out; recruiting female, Caucasian participants aged 18-65 years. The relevance of candidate gene studies is disputed.
- Trial name
- NCT03666182
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Pancreatic Cancer
Comparing Parenteral Nutrition vs Best Supportive Nutritional Care in Patients With Pancreatic Cancer
A randomised multicentre clinical phase IIIb trial for patients suffering from pancreatic adenocarcinoma receiving defined second or higher line chemotherapy and additionally parenteral nutrition (study arm A) or best supportive…
- Trial name
- PANUSCO (NCT01362582)
- Testing
- SMOF Kabiven
- Where
- 4 sites in Germany
- Volunteers
- 32 people
- Sponsor
- National Center for Tumor Diseases, Heidelberg
Physician Well-being, Cognitive Function
Performance Nutrition for Residents and Fellows
Currently, residents commonly experience dehydration and poor nutrition during nighttime duty hours as a result of heavy work load, lack of time to take nutrition and hydration breaks, or limited or no access to healthy food and…
- Conditions
- Physician Well-being, Cognitive Function, Diet Modification, Diet Habit
- Trial name
- NCT03698123
- Testing
- Dietary Modification
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Non-Alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic
Effects of Mindfulness Based Stress Reduction Intervention in Patients With Non-alcoholic Fatty Liver Disease
The purpose of this research study is to find out about the usefulness of mindfulness for weight loss and improvement of physical and mental health in people who have non-alcoholic fatty liver disease (NAFLD).
- Conditions
- Non-Alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic, Obesity
- Trial name
- NCT05130346
- Testing
- Mindfulness Based Stress Reduction (MBSR)
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Obesity
Secretin Activates Human Brown Fat and Induces Satiation.
15 healthy males will be studied with PET/CT, using FDG to investigate glucose metabolism, and radiowater to investigate perfusion.
- Trial name
- GUTBAT (NCT03290846)
- Testing
- Secretin Human, Saline Solution, Cold exposure
- Where
- Finland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity, Weight Loss
Project Impact: An Innovative Approach to Weight Loss Maintenance
The major goal of this project is to evaluate an innovative approach to obesity. This study will determine if behavioral treatment can be improved by 1) implementing a primary focus on PA following initial weight loss treatment…
- Conditions
- Obesity, Weight Loss, Overweight
- Trial name
- NCT02363010
- Testing
- Gold Standard Behavior Therapy for Weight Loss, Behavior Therapy for Weight Loss with Physical Activity Emphasis, Acceptance-based Behavior Therapy for Weight Loss with PA emphasis
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Drexel University
Vitamin A Deficiency in Children
The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia
Based on recent nutrition survey (SEANUTS Malaysia) on a total of 3542 Malaysian Children aged between 6 months to 12 years old, 4.4% of the children had vitamin A deficiency.
- Trial name
- NCT03256123
- Testing
- red palm shortening group, palm shortening group
- Where
- Malaysia
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Pneumonia, Vitamin D Deficiency
Kabul Vitamin D Supplementation Trial
Background: Pneumonia is the leading cause of childhood mortality, accounting for 19% of the 10.6 million deaths that occur each year1.
- Trial name
- NCT00548379
- Testing
- vitamin D
- Where
- 2 sites in Afghanistan
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Obesity
The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity
The primary aim of the study is to investigate the efficacy of metformin and topiramate on second-generation antipsychotic-induced obesity. The secondary domain we look at is the adverse effects of both drugs.
- Trial name
- NCT01384279
- Testing
- metformin, topiramate
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Beitou Armed Forces Hospital, Taipei, Taiwan
Obesity, Diabetes
Effects of High-Dose Resveratrol in Non-Diabetic Obese Males
The primary aim of our study was to examine the effects of two weeks of oral resveratrol on resting energy expenditure and insulin sensitivity in non-diabetic obese male subjects.
- Trial name
- NCT02247596
- Testing
- Resveratrol
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Khoo Teck Puat Hospital
Breast Feeding
Infant Nutrition in Austria
This study will give an update on the breastfeeding prevalence and infant nutrition in Austria. Key aspects for this study are: 1. the current breastfeeding rates 2.
- Trial name
- Sukie (NCT04137796)
- Where
- Austria
- Volunteers
- 1,666 people
- Sponsor
- Karin Schindler
Poor Nutrition
Acceptability and Tolerance of a Protein and Micronutrient Fortified Food
Acceptability and tolerance of a new food product in adults and children.
- Trial name
- NCT03041103
- Testing
- Food Product 1
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Sedentary Behavior
Effect of Walking With Music in Obese People (BeatMove)
For several decades, scientists have reported encouraging effects of physical activity on functional capacities and quality of life among patients with obesity.
- Trial name
- BeatMove (NCT06486961)
- Testing
- BeatMove Application, BeatMove Application without synchronized music, BeatMove Application without music
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Clinique Beau Soleil
Adiposity
Dietary Carbohydrate and Internal Body Fat
This is a 2-year randomized controlled trial to test the effect of dietary carbohydrates, both quality and quantity, on changes in internal body fat mass.
- Trial name
- CARBFUNC (NCT03401970)
- Testing
- Acellular carbohydrate diet, Cellular carbohydrate diet, Low-carbohydrate high-fat diet
- Where
- Norway
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Diabetes type2, Obesity
The RESET System Pivotal Clinical Trial (Protocol Revision K)
A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the RESET System for Glycemic Improvement in Patients with Inadequately Controlled Type 2 Diabetes and Obesity, the STEP-1 Study.
- Trial name
- STEP-1 (NCT04101669)
- Testing
- RESET Liner
- Where
- 27 sites in United States
- Volunteers
- 264 people
- Sponsor
- Morphic Medical Inc.
Vitamin D Deficiency, Sickle Cell Disease
Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France
Vitamin D deficiency may be under-diagnosed in sickle cell disease French children. Therefore, the investigator need an epidemiologic study about the prevalence of vitamin D deficiency in this specific population.
- Trial name
- EVADDREP (NCT04694976)
- Testing
- 25-OH Vitamin D measure
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Hospices Civils de Lyon
Obesity, Mentally Ill Persons
Interactive Obesity Treatment Approach (iOTA) for Obesity Prevention in Serious Mental Illness
The proposed project aims to pilot and adapt a scalable and sustainable interactive obesity treatment approach (iOTA) program for adults with serious mental illness (SMI).
- Trial name
- iOTA-SMI (NCT03695289)
- Testing
- iOTA SMI, Health Education Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency, Surgery
Effects of Stoss Therapy of Vitamin D3 on Peri-operative Outcomes in Patients Receiving General Surgery
To investigate whether preoperative supplement with high-dose vitamin D3 can reduce the perioperative risk and enhance recovery
- Trial name
- NCT05650268
- Testing
- Vitamin D3, 95% MCT
- Sponsor
- National Taiwan University Hospital
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