Clinical trials: Nutrition Sciences
Obesity, Physical Activity
Leisure Time Activity and Nutrition Program
The purpose of this investigation is to conduct an 8-week pilot study to examine the effects of two different leisure-time activity prescriptions on dietary intake, leisure-time activities, and weight loss in 26 adults receiving…
- Trial name
- LEAN (NCT00656045)
- Testing
- Dietary, Physical Activity, TV Watching
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity, Healthy
Sphingo-lipotoxicity and Trans-differentiation of Adipose Tissue in Obesity (SFINGOTRANS)
After recruiting a population of subjects with different metabolic severity (subjects of normal weight and obese patients with and without metabolic syndrome), the objectives of the present research will be: 1.
- Trial name
- SFINGOTRANS (NCT05761145)
- Testing
- Blood sample collection
- Where
- Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Chronic Disease, Hypertension
Rehabilitation in Primary Care: A Project to Maximize the Health Status of Adults With Chronic Illness
The purpose of the study is to determine whether occupational therapy and physiotherapy delivered in a primary care setting to adults with chronic illness is effective in improving health.
- Conditions
- Chronic Disease, Hypertension, Back Pain, Obesity
- Trial name
- NCT00229957
- Testing
- Occupational therapy, Physiotherapy, Self-management
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Hamilton Health Sciences Corporation
Muscle Atrophy, Aging
The Impact of Energy Intake and Short-term Disuse on Muscle Protein Synthesis Rates and Skeletal Muscle Mass in Middle-aged Adults.
In healthy middle-aged men and women, what is the effect of dietary energy restriction and energy surplus on daily muscle protein synthesis rates and muscle morphology, compared to energy balance, during free-living and…
- Conditions
- Muscle Atrophy, Aging, Energy Malnutrition Protein
- Trial name
- PIE (NCT04900701)
- Testing
- Energy status
- Where
- 2 sites in United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Obesity, Childhood
Cleveland Clinic Families Get Fit (CCFit) : A Family-based Activity-Monitor Intervention in Pediatric Obesity
This is a randomized prospective study to evaluate the effectiveness of a family-based intervention using activity-monitors (I.e.
- Trial name
- CCFit (NCT04312919)
- Testing
- Family Based Activity Intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- The Cleveland Clinic
Obesity & Overweight
Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment
This clinical trial is focused on testing dietary self-monitoring strategies used in behavioral obesity treatment. The goal is to determine which self-monitoring strategies are most useful for whom, at which points in treatment…
- Trial name
- NCT07228130
- Testing
- Online Behavioral Obesity Treatment, Full Dietary Self-monitoring, Reduced-frequency Dietary Self-monitoring
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- The Miriam Hospital
Overweight, Family Relations
Reducing Obesity Health Disparities in Hispanic Youth
The proposed study will evaluate the efficacy of a family-based obesity prevention intervention in increasing physical activity and improving the quality of dietary intake among Hispanic Youth.
- Conditions
- Overweight, Family Relations, Adolescent Behavior, Drug Use
- Trial name
- NCT03943628
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of Miami
Metabolism and Nutrition Disorder, Obesity
Safety, Efficacy, Tolerability and Pharmacokinetics of NNC 0070-0002-0182 in Overweight or Obese Male and Female Volunteers
This trial will be conducted in the United States of America (USA). The aim of the trial is to investigate whether the drug is safe, well tolerated and to investigate the efficacy of NNC 0070-0002-0182 for the treatment of…
- Trial name
- NCT00665665
- Testing
- NNC 0070-0002-0182
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Hypertension
Changes After Angiotensin Converting Enzyme (ACE) Inhibitor Replacement by Angiotensin II Receptor Type I (AT1) Blocker
It is supposed that the significant metabolic effects (improvement of insulin sensitivity) of hypertension therapy with renin-angiotensin system (RAS) blockers in humans are mediated mainly via changes in abdominal adipose…
- Trial name
- ADIRAS (NCT01444833)
- Testing
- Candesartan
- Where
- Slovakia
- Volunteers
- 35 people
- Sponsor
- Slovak Academy of Sciences
Type 2 Diabetes Mellitus (T2DM), Obesity Type 2 Diabetes Mellitus
Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus
This prospective observational study aims to evaluate serum Neuregulin-4 (NRG4) concentrations in obese and non-obese adults with Type 2 Diabetes Mellitus (T2DM) and to investigate their association with obesity status, insulin…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NRG4-T2DM (NCT07734558)
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- GÜLDEN ANATACA
Child Overnutrition
ChildObesity180 - Social Marketing Campaign to Encourage Healthful Eating in Restaurants for Children
The purpose of this study is to determine whether a messaging campaign affects the calories ordered for and consumed by children in a quick serve restaurant setting.
- Trial name
- CO180 (NCT03422926)
- Testing
- Social marketing campaign
- Volunteers
- 2,646 people, healthy volunteers welcome
- Sponsor
- Tufts University
Endothelial Dysfunction, High Blood Pressure
Inulin and Nitrate's Effects on Vascular Health and Gut Microbiome
Previous research has revealed that adults with pre-hypertensive and hypertensive blood pressure levels typically exhibit impaired vasodilation, which is a crucial aspect of blood vessel function, due to decreased nitric oxide…
- Conditions
- Endothelial Dysfunction, High Blood Pressure, Gut Microbiota Dysbiosis and Nutrition
- Trial name
- NCT06502535
- Testing
- Inulin, Potassium nitrate and inulin
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Exeter
Metabolism, Trauma
ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with…
- Conditions
- Metabolism, Trauma, Nutritional Deficiency, Protein Malnutrition
- Trial name
- ACCUMULATE (NCT05647135)
- Testing
- Medical food
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Advanced Ovarian Cancer
SOPHIE Trial: Surgery in Ovarian Cancer With PreHabilitation In ERAS
The treatment of choice in advanced ovarian cancer is a cytoreductive surgery combined with chemotherapeutic treatment. This complex and aggressive surgery is associated with high postoperative complication rates that may result…
- Trial name
- SOPHIE (NCT04862325)
- Testing
- Multimodal Prehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity; Endocrine
Vitamin D and Its Metabolites Quantification in Adipose Tissues of Obese and Non-obese Patients.
Vitamin D (VD) is a pleiotropic hormone, involved in many physiological processes including calcium and phosphorus absorption. The VD metabolism begin to be well-known and involves a hepatic hydroxylation (mediated by enzymes…
- Trial name
- VITADOSE (NCT03008525)
- Testing
- subcutaneous and visceral adipose tissue biopsies, blood samples analysis
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Obesity
ULTIMATE Study for Weight Loss
The purpose of this study is to help find out more about how the Primary Obesity Surgery Endoluminal (POSE) procedure makes patients feel less hungry and fuller faster, leading to weight loss.
- Trial name
- ULTIMATE (NCT01771276)
- Testing
- g-Cath Suture Anchor Delivery Catheter
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- USGI Medical
Subjective Tinnitus, Obesity
The Effects of Weight Loss on Tinnitus Symptoms
Subjective tinnitus is the perception of irregular sound at different frequencies. Although the underlying cause of tinnitus is unclear, increased body weight is known to increase tinnitus symptoms.
- Trial name
- NCT05265949
- Testing
- diet and physical activity intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Ankara University
Obesity, Adult
Effect of Probiotics Among Overweight and Obese Saudi Adults
Obesity is classified as a low-grade chronic and systemic inflammatory disease and results from complicated interactions between genes and environmental factors, which leads to many diseases and affects the quality of life.
- Trial name
- NCT05667038
- Testing
- Probiotic
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King Saud University
Inflammation, Malnutrition
Effects of Camelina Sativa Oil in Free-living Older Adults
The present study aims at evaluating the anti-inflammatory effects of a novel food in older adult volunteers. Briefly, this randomized, double-blind and placebo-controlled study is performed on 91 apparently healthy older adults…
- Conditions
- Inflammation, Malnutrition, Hyperglycemia, Dyslipidemias
- Trial name
- NCT04965948
- Testing
- Novel food snack
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Morbid Obesity
Comparison of Mini Gastric Bypass and Roux-en-Y Gastric Bypass
This study compares Roux-en-Y gastric bypass with single anastomosis gastric bypass in a randomized prospective setting. This study also adresses the issue of bile reflux after MGB.
- Trial name
- RYSA (NCT02882685)
- Testing
- Roux-en-y gastric bypass, Single anastomosis gastric bypass
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital
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