Clinical trials: Nutrition and Energy Balance
Protein-Energy Malnutrition
Usefulness of Protein-enriched Infant Formula in Pediatric Intensive Care.
A multicenter prospective randomized controlled trial (RCT) will be performed in three hospitals. Patients meeting inclusion criteria will be randomly allocated to one of three enteral feeding formula with different protein…
- Trial name
- NCT03901742
- Testing
- Protein-enriched nutrition, High Protein-enriched Nutrition, Standard Enteral Nutrition
- Where
- 3 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Obesity, Weight Gain
Effects of Monosodium Glutamate on Energy Balance and Eating Behavior
This study will test whether regular consumption of Monosodium Glutamate (MSG) immediately prior to each of the three major meals (breakfast, lunch, dinner) inhibits body weight and fat regain following a period of moderate, yet…
- Conditions
- Obesity, Weight Gain, Food Preferences
- Trial name
- NCT01410838
- Testing
- Broth
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Type 1 Diabetes
The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes
The purpose of this study is to measure the metabolic phenotype of a range of body weights in individuals with and without type 1 diabetes.
- Trial name
- ACME (NCT03379792)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Abdominal Obesity
Multi-component Workplace Energy Balance Intervention
The purpose of the WorkACTIVE-P study is to assess the outcome of an innovative multi-component intervention focused on increasing energy expenditure and re-balancing the disrupted energy balance equation of sedentary workplaces…
- Trial name
- WorkACTIVE-P (NCT02561611)
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pennington Biomedical Research Center
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Vascular Stiffness, Hypertension (HTN)
Low Energy Availability and Hypertension in Division I HBCU Athletes
Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs.
- Conditions
- Vascular Stiffness, Hypertension (HTN), Nutritional Deficiency Related Cardiovascular Risk in Athletes
- Trial name
- CORE-DI (NCT07583940)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Overweight, Breast Cancer
Appetite and Exercise in Breast Cancer Survivors
The overall aim of this research is to investigate the acute effects of resistance exercise (REx) on the hormonal and behavioral indices of energy balance regulation in breast cancer survivors.
- Conditions
- Overweight, Breast Cancer, Obesity
- Trial name
- EARNESt (NCT04300478)
- Testing
- REx Condition First, Sedentary Control Condition First
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of Colorado, Denver
Body Mass Index 25 or Greater, BRCA1 Gene Mutation
Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members
This pilot clinical trial studies different types of energy balance interventions to see how well they work in increasing the physical activity levels of breast cancer gene-positive patients, Lynch syndrome-positive patients…
- Conditions
- Body Mass Index 25 or Greater, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Breast Carcinoma
- Trial name
- NCT02194387
- Testing
- Dietary Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer, Obesity
Energy Balance Interventions for Colorectal Cancer Prevention
RATIONALE: Calories and physical exercise may affect the risk of developing cancer. It is not yet known whether a low-calorie diet and/or physical activity program is effective in preventing cancer in participants at increased…
- Trial name
- NCT00653484
- Testing
- Physical Activity, Energy Restriction, Physical Activity and Energy Restriction
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University
Physical Activity, Diet Modification
Dietary Carbohydrate Manipulation and Energy Balance: RCT
This study will investigate how dietary sugar and carbohydrates influence metabolism and health across a 12-week period, with a focus on physical activity.
- Trial name
- NCT03574987
- Testing
- Diet
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bath
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Obesity and Overweight
Intermittent Carbohydrate Restriction in Cardiometabolic Health
Metabolic conditions, such as heart disease, type 2 diabetes, and metabolic syndrome, are among the leading causes of disability and mortality worldwide.
- Trial name
- NCT06684834
- Testing
- 5:2 carbohydrate restriction, Early time-restricted carbohydrate intake
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bath
Overweight
Acute Effects of Different Protein Sources and Different Glycemic Index on Energy Balance, Glucose Allostasis and Amino Acid Metabolism: a Randomized, 4-condition, Two Cross-over Study in Adults.
The hypothesis is that seafood proteins given in combination with carbohydrates with low GI are superior to seafood proteins in combination with carbohydrates with high GI and meat in combination with both carbohydrates with low…
- Trial name
- FINS (NCT02770833)
- Testing
- Fish and carbohydrats with low or high GI, Veal and carbohydrats with low or high GI
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Digestibility
Effects of Time-restricted Eating on Nutrient Absorption in Healthy Adults
This 2-period, crossover, controlled-feeding trial will investigate the effects of early time-restricted eating (8am-2pm), compared to a control eating timeframe (8am-8pm), on energy and macronutrient digestibility, the thermic…
- Trial name
- NCT04877262
- Testing
- weight maintenance diet (WMD)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Florida State University
Insulin Resistance
Meal Pattern and Metabolic Parameters
In this study investigators will compare the health effect of two different meal patterns. In one, participants will consume food according to an 'irregular meal pattern' (minimum 3 meals, maximum 9 meals per day) and in the…
- Trial name
- NCT02582606
- Testing
- Regular meal pattern, Irregular meal pattern
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Obesity
Effect of Tesofensine on Energy Balance in Humans.
Purpose: To evaluate the effect of tesofensine on energy balance
- Trial name
- NCT00428415
- Testing
- Tesofensine
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NeuroSearch A/S
Obesity, Sleep
Effects of Impaired Sleep on Energy Balance
The main aim of this study is to examine the effects of restricted sleep on energy and substrate metabolism as well as relevant hormonal systems that might be involved in the underlying mechanisms.
- Trial name
- SLOPUS (NCT01198431)
- Testing
- Sleep duration
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Low Oxygen Exposure and Weight Status
The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of…
- Trial name
- LOWS (NCT05289310)
- Testing
- Normobaric hypoxia (NH), Normobaric normoxia (NN)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Overweight
The Relationship of TV Viewing to Energy Balance in Adults
The specific objectives of this project are to: 1. Investigate the effects of reducing TV viewing time on energy intake, eating behavior, and energy expenditure in overweight or obese adult subjects, thus providing a basis for…
- Trial name
- TView (NCT00622050)
- Testing
- No TV viewing reduction, TV viewing reduction
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Obesity, Nutritional Deficiencies
Assessment of Nutritional Status After Gastric Bypass Surgery
This study is aimed at assessing how Roux-en-Y gastric bypass (RYGP) impacts on energy and nutrients' intake, energy expenditure, and nutritional status in obese patients.
- Trial name
- NCT01891591
- Testing
- Roux-en-Y gastric bypass (RYGP)
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University of Lausanne