Clinical trials: Nutritional Deficiencies
Amyotrophic Lateral Sclerosis
Systematic Laryngoscopic Evaluation of Upper Airways in Ventilated ALS Patients in Portugal and in Norway
The study examines if titration of Non-Invasive mechanical ventilation (NIV) settings during ongoing laryngoscopic visualization can improve the compliance of NIV in subjects with Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT03887338
- Testing
- Transnasal Fiberoptic Laryngoscopy
- Where
- 2 sites in Norway, Portugal
- Volunteers
- 60 people
- Sponsor
- Tiina Maarit Andersen
Stroke, Neurologic Diseases, General
Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy
The main objective of this study is to evaluate the safety, tolerability and pharmacokinetics of Cerebril™ in Cerebral Amyloid Angiopathy (CAA) patients who have had lobar cerebral hemorrhage.
- Trial name
- NCT00056238
- Testing
- NC-758 (Anti amyloidotic [Aß] agent)
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Bellus Health Inc. - a GSK company
Water-Related Diseases
SAFEWATER Health & Behaviour Impact Field Trials; Mexico
At least 1.8 billion people globally use a source of drinking water that is faecally contaminated and thus likely to lead to diarrheal illness: nearly 1,000 children die each day due to water and sanitation-related diarrhoeal…
- Trial name
- NCT04736615
- Testing
- SAFEWATER systems for drinking water disinfection, Behavior change interventions
- Where
- 3 sites in Colombia, Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Anemia, Folate Deficiency
Quadruple Fortified Salt Trial in India
Women of reproductive age are at an increased risk of anemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of neural tube defects and other pregnancy complications.
- Conditions
- Anemia, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- QFS (NCT03853304)
- Testing
- + Folic acid, + Vitamin B12, DFS
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cornell University
Anemia, Iron Deficiency, Anemia of Chronic Disease
Anemia of Inflammation and Deficiency Anemia
Critical patients which requiring admission to intensive care (IT) are a special group of patients. In these patients the prevalence of anemia reported in studies is 75%.
- Trial name
- AIDA (NCT04071067)
- Where
- 2 sites in Romania
- Volunteers
- 1,000 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Iron Deficiency Anaemia, Iron Deficiency Anemia
Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose vs Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
The trial was designed to evaluate the incidence of unintended hypophosphatemia (low level of phosphate in the blood) in subjects with iron deficiency anaemia (IDA).
- Trial name
- NCT03238911
- Testing
- Iron isomaltoside/ferric derisomaltose, Ferric carboxymaltose
- Where
- 16 sites in United States
- Volunteers
- 123 people
- Sponsor
- Pharmacosmos A/S
Iron Deficiencies
Impact of Two Iron Formulations on Iron Biomarkers and Quality of Life
This double-blind parallel pilot study will evaluate the safety and efficacy of two Qualia Iron formulations versus placebo in approximately 40 healthy adults (aged 18+) over a 56-day period.
- Trial name
- NCT07156526
- Testing
- Qualia Iron Version A, Qualia Iron Version B
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Amyotrophic Lateral Sclerosis (ALS)
A Study for Patients Who Completed VITALITY-ALS (CY 4031)
The purpose of this study is to assess the long-term safety and tolerability of tirasemtiv in patients with ALS who had completed the double-blind placebo-controlled study of tirasemtiv in ALS (CY 4031).
- Trial name
- VIGOR-ALS (NCT02936635)
- Testing
- tirasemtiv
- Where
- 67 sites in United States, Belgium and 9 more
- Volunteers
- 280 people
- Sponsor
- Cytokinetics
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Nutrition
Evaluation of a Rwanda Hospital Feeding Program on Nutrition, Recovery, Costs of Care and Health Related Quality of Life
The purpose of this interventional study was to evaluate outcomes for Solid'Africa's Gemura feeding program in four selected public hospitals comparing results between patients receiving and patients not receiving the feeding…
- Trial name
- NCT06852885
- Testing
- Meals
- Where
- 4 sites in Rwanda
- Volunteers
- 794 people
- Sponsor
- Solid'Africa
Amyotrophic Lateral Sclerosis
Frequency of SOD1 and C9orf72 Gene Mutations in French ALS
The purpose of the study is to determine the frequency of mutations in the C9orf72 and SOD1 genes in the incident population of ALS patients followed in the FILSLAN centres
- Trial name
- GENIALS (NCT04819555)
- Testing
- Blood
- Where
- 20 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Tours
Amyotrophic Lateral Sclerosis
Study to Investigate the Long-term Safety of FAB122 in Patients With Amyotrophic Lateral Sclerosis
A multicenter, open-label extension study to investigate the long-term safety of FAB122 in patients with Amyotrophic Lateral Sclerosis
- Trial name
- ADOREXT (NCT05866926)
- Testing
- FAB122
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Ferrer Internacional S.A.
Vitamin D Deficiency, Nutritional Deficiency
Mothers' Own Milk Optimization for Preterm Infants Project (MoMO PIP) Pilot Study
The overall goal of this study is to assess maternal vitamin D status along with diet, and milk composition, and in turn, to evaluate if infant vitamin D status can be improved with increased maternal supplementation and diet…
- Trial name
- MoMO PIP (NCT04629534)
- Testing
- High dose Cholecalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical University of South Carolina
Malnutrition
Trial to Test the Growth-Promoting Effect of Fortified Spreads When Used as Complementary Food for Infants
This study tests the hypothesis that infants receiving fortified spread as a complementary food for one year grow better and do not become malnourished as often as infants who are provided with maize-soy flour for complementary…
- Trial name
- NCT00131209
- Testing
- fortified spread (RUTF), maize and soy flour
- Where
- Malawi
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tampere University
Amyotrophic Lateral Sclerosis
Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
This study evaluates the effect of retigabine (600 mg/day, 900 mg/day, or placebo) on motor neuron activity in people with Amyotrophic Lateral Sclerosis (ALS). The total study duration is approximately 14 weeks.
- Trial name
- NCT02450552
- Testing
- Ezogabine
- Where
- 12 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Brian Wainger
HIV, Pregnancy
Maternal Determinants of HIV-exposed and HIV-unexposed Fetal Growth, Birth Outcomes and Early Infant Growth
The purpose of this study is to understand how differences in the nutritional status and concentration of hormones and cytokines associated with cachexia in HIV+ and HIV- pregnant women living in a semi-rural and rural region of…
- Conditions
- HIV, Pregnancy, Malnutrition, Cachexia
- Trial name
- NCT01647841
- Where
- Tanzania
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Cornell University
Iron Deficiency (Without Anemia), Pregnancy Related
Ferritin Screening And IRon Treatment for Maternal Anemia and FGR Prevention Trial
Prevalence of anemia in Asia is more than 50%. All woman who book for antenatal care with non-anaemic iron deficiency (NAID) can be offered therapeutic doses of parentral iron, as a directly observed complete therapy, to prevent…
- Trial name
- FAIR (NCT04228627)
- Testing
- Parentral Iron
- Where
- 3 sites in Pakistan
- Volunteers
- 600 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Cerebral Amyloid Angiopathy Related Inflammation
Use Lay Language. CAA-ri : a Series of 28 Patients
INTRODUCTION: Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a very rare manifestation of cerebral amyloid angiopathy, characterized by acute/subacute neurological deterioration and T2/FLAIR corticosubcortical or…
- Trial name
- NCT03187886
- Volunteers
- 28 people
- Sponsor
- University Hospital, Montpellier
Poor Nutrition
Using Spices and Herbs to Increase Vegetable Intake Among Urban High School Students
A two-phase, school-based intervention will be conducted at a high school in Baltimore to evaluate whether the addition of spices and herbs to vegetable dishes in the National School Lunch Program (NSLP) can increase vegetable…
- Trial name
- NCT02908854
- Testing
- Adding spices and herbs to school lunch vegetables
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sarcopenic Obesity, Frailty
Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE
The study will be conducted in a group of obese sarcopenic patients (Sarco-Ob) aged > 60 years on moderately hypocaloric diet therapy aimed at comparing the effect of a strength exercise protocol, combined or not with dietary…
- Conditions
- Sarcopenic Obesity, Frailty, Malnutrition; Protein
- Trial name
- MAYBE (NCT05938205)
- Testing
- AA-1, AA-2, Exe-H
- Where
- Italy
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
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