Clinical trials: Nutritional Deficiencies
Moderate Acute Malnutrition (MAM)
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition (MAM) in Children in Sierra Leone: a Cluster-randomised, Controlled Clinical Effectiveness Trial
The objective of this study is to test and compare the effectiveness and cost-effectiveness of four supplementary foods for the treatment of moderate acute malnutrition (MAM) in normal programmatic settings in Sierra Leone.
- Trial name
- NCT02077907
- Testing
- Super Cereal Plus (SC+), Super Cereal (SC), fortified oil, sugar, Plumpy Sup
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Tufts University
Iron Deficiency
Iron Bioavailability From Cubes
Iron deficiency is a highly prevalent nutrient deficiency which is a public health problem, especially in developing countries. There are several strategies to correct iron deficiency in populations: besides supplementation with…
- Trial name
- Fe Bouillon (NCT02327299)
- Testing
- Bouillon fortified with FePP, Bouillon fortified with FePP + Stabilizer, Bouillon fortified with FeSO4
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Amyotrophic Lateral Sclerosis
Investigation on Home Care Needs of ALS Patients and Their Caregivers
The research target 1. To investigate the home nursing knowledge needs of ALS patients; 2. Investigate the needs of ALS caregivers for home nursing knowledge; 3.
- Trial name
- NCT04950231
- Testing
- The questionnaire survey
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Third Hospital
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Malnutrition
Mesalamine in Environmental Enteropathy
Undernutrition is one of the most important health issues in Kenya. Children who are chronically undernourished do not reach their full potential and are at increased risk of infectious disease.
- Trial name
- NCT01841099
- Testing
- Mesalamine
- Where
- Kenya
- Volunteers
- 44 people
- Sponsor
- Kelsey Jones
Iron-deficiency, Iron Deficiency Anemia
Child of Urban Poverty Iron Project (CUPIP) - A Pilot Study
The first 1,000 days of life are critical periods for brain development. Proper nutrition lays the foundation for optimal growth, health, and neurodevelopment across the lifespan.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Micronutrient Deficiency, Nutrient Deficiency
- Trial name
- CUPIP (NCT03819530)
- Testing
- Vitamin and Mineral Powder
- Where
- Malaysia
- Volunteers
- 45 people
- Sponsor
- University of Malaya
Ataxia Telangiectasia
Body Composition and Hormonal Status in Ataxia Telangiectasia
Ataxia telangiectasia (A-T) is a rare devastating human recessive disorder characterized by progressive cerebellar ataxia, immunodeficiency, chromosomal instability, and cancer susceptibility.
- Trial name
- NCT02345200
- Testing
- bioelectrical impedance analysis, blood draw
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Vitamin D Deficiency, Vitamin D3 Deficiency
Development of a Screening Tool for the Risk of Vitamin D Deficiency
Since vitamin D deficiency is a condition that affects a high percentage of individuals of all ages and given the attention on the possible role of the deficiency of this vitamin in the development of various chronic diseases…
- Conditions
- Vitamin D Deficiency, Vitamin D3 Deficiency, Vitamin D
- Trial name
- EvidenceQ (NCT04404842)
- Where
- Italy
- Volunteers
- 190 people
- Sponsor
- University of Pavia
PCOS, Vitamin D Deficiency
Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women
This study is determining the therapeutic effect of Vitamin D supplements to Pcos clomiphene resistant polycystic ovarian syndrome Women. Half of patients will receive Vitamin D with metformin while other half metformin only.
- Trial name
- NCT04010942
- Testing
- Vit D, Metformin, Clomiphene
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Crohn's Disease, Vitamin D Deficiency
Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's Disease
IBD is caused by an abnormal immune response to the gut bacteria in people who are genetically predisposed. There has been a huge increase in the number of people diagnosed with IBD since World War II, likely due to changes in…
- Trial name
- NCT01046773
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, Los Angeles
Burns, Critical Illness
Indirect Calorimetry in Patients at Risk of Malnutrition
Burn patients treated in an outpatient clinic and ICU survivors are at risk of malnutrition. There are no clear guidelines determining the energy target in those two populations.
- Conditions
- Burns, Critical Illness, Indirect Calorimetry, Resting Energy Expenditure
- Trial name
- NCT04500483
- Testing
- indirect calorimetry
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Child Malnutrition, Child Allergy
The UFIM (Ultraprocessed Foods In Breast Milk) Project
In last decades, a change in dietary habits has been observed in industrialized countries characterized by a drastic increase in the consumption of ultra-processed foods (UPF, Ultra-Processed Foods).
- Conditions
- Child Malnutrition, Child Allergy, Maternal Exposure
- Trial name
- UFIM (NCT05889520)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus
Effects of High Intensity Statin Therapy on Steroid Hormones and Vitamin D in Type 2 Diabetic Men
The aim of the study was to assess the effect of high intensity statin therapy on testicular and adrenal steroids and vitamin D levels in type 2 diabetes males.It is a prospective study, conducted between march 2021 and July…
- Conditions
- Diabetes Mellitus, Type 2, Dyslipidemia Associated With Type II Diabetes Mellitus, Statin Adverse Reaction, Hypogonadism, Male
- Trial name
- NCT05806723
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Hopital La Rabta
Maintenance Dose, Osteocalcin
Estimation of a Maintaining Daily Jarlsberg Cheese-dose
The study objective is to estimate a maintaining daily dose of Jarlsberg cheese in healthy pre-menopausal women obtaining an increase in the osteocalcin level of at least 10% after 6 weeks on maximum efficacy dose (MED) of…
- Conditions
- Maintenance Dose, Osteocalcin, Vitamin K Deficiency
- Trial name
- NCT04188080
- Testing
- Jarlsberg Cheese
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Meddoc
Growth Retardation, Malnutrition
Nutrition Education Package for Infants and Young Child Feeding and Health in Rural Tanzania
Building on the success of community-based peer education and counselling in breastfeeding, it is possible to address young child feeding and health practices in the surveyed district.
- Trial name
- NECTAc (NCT02249754)
- Testing
- Nutrition education, Routine health education
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sokoine University of Agriculture
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Amyotrophic Lateral Sclerosis
Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 Administered to Previously Treated Adults C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS)
The primary objective is to evaluate the long-term safety and tolerability of BIIB078 in participants with chromosome 9 open reading frame 72-amyotrophic lateral sclerosis (C9ORF72-ALS).
- Trial name
- NCT04288856
- Testing
- BIIB078
- Where
- 21 sites in United States, Canada and 3 more
- Volunteers
- 75 people
- Sponsor
- Biogen
Amyotrophic Lateral Sclerosis
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects With Amyotrophic Lateral Sclerosis (ALS) With Superoxide Dismutase Type 1 (SOD1) Gene Mutation
This is a Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects with Amyotrophic Lateral Sclerosis (ALS) with Superoxide…
- Trial name
- NCT06556394
- Testing
- RAG-17
- Where
- 3 sites in China
- Volunteers
- 32 people
- Sponsor
- Ractigen Therapeutics.
Vitamin D Deficiency
The Effect of Vitamin D Supplements on Vitamin D Status, Cardiometabolic Health and Immune Defense in Danish Children
The main purpose of this study is to investigate whether and in which doses vitamin D intake is needed in order to maintain an adequate vitamin D status in 4-8 year-old Danish children during wintertime.
- Trial name
- ODIN Junior (NCT02145195)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
GI Cancer, Nutritional Deficiency
Mobile APP Utilization for Enhanced Post-Operative Nutritional Recovery
This study is to assess the usability and acceptability of a digital food consumption diary as part of the perioperative management of gastrointestinal oncology patients and to evaluate the impact of a digital food diary on…
- Trial name
- NCT04091165
- Testing
- My Plate Calorie Tracker
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
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