Clinical trials: Nutritional Deficiencies
Cardiac Amyloidosis, Chest Pain
CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD).
- Trial name
- CHEST-CA (NCT07435168)
- Testing
- Screening thourgh examinations including bonescintigraphy
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vitamin D Deficiency, Chemotherapy Effect
Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy
The aim of the study is to evaluate the relationship between the vitamin D replacement and pathological response in patients undergoing neoadjuvant therapy according to different molecular sub types.
- Conditions
- Vitamin D Deficiency, Chemotherapy Effect, Pathology
- Trial name
- NCT03986268
- Testing
- Vit D
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Malnutrition, Anemia
Microfinance Institutions as a Platform for Global Health
This study will analyze data from a program run by an microfinance institution (MFI) in Haiti from 2011-2012 where the MFI delivered health goods to some of the villages where it operates.
- Trial name
- NCT02808117
- Testing
- MNP
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- Columbia University
Refractory Iron Deficiency Anemia
Endoscopy in Anemic Children
Assess the role of Upper and lower gastrointestinal endoscopy in evaluation of refractory iron deficiency anemia in children
- Trial name
- NCT06729489
- Testing
- Upper Endoscopy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Neurogenic Dysphonia, Neurogenic Dysphagia
Neurogenic Dysphonia/Dysphagia Registry
The Neurogenic Dysphonia/Dysphagia Registry is designed to be purely observational (i.e. non-interventional, exploratory). Patient data collected from the registry is expected to be consistent with any information which can be…
- Trial name
- StrongVoice (NCT02493491)
- Where
- 12 sites in United States
- Volunteers
- 146 people
- Sponsor
- Merz North America, Inc.
Transthyretin (TTR) Amyloid Cardiomyopathy
An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.
This is a multi-center, observational study with the overall objective to examine the scale of under-diagnosis for transthyretin amyloid cardiomyopathy (ATTR-CM) across a broad range of diverse health systems in the US using a…
- Trial name
- TRACE Network (NCT07062848)
- Testing
- AI Toolkit for ATTR-CM Diagnosis
- Where
- 12 sites in United States
- Volunteers
- 1,500,000 people
- Sponsor
- Yale University
Obesity, Childhood, Vitamin D Deficiency
The Changes of Body Composition, Glucolipid Metabolism and Bone Metabolism in Obese Children After Weight Loss
Vitamin D plays a significant role in calcium and phosphorus homeostasis for maintaining structural integrity and function of musculoskeletal system.
- Trial name
- NCT03490448
- Testing
- aerobic exercise and appropriate caloric control
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Amyotrophic Lateral Sclerosis
A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)
This study aims to evaluate the safety of ARGX-119 in adults with ALS. The study will also assess the impact of ARGX-119 on ALS disease outcomes, including muscle function.
- Trial name
- ReALiSe (NCT06441682)
- Testing
- ARGX-119
- Where
- 9 sites in Belgium, Canada and 4 more
- Volunteers
- 60 people
- Sponsor
- argenx
Vitamin D Deficiency, Military Activity
Vitamin D Supplementation in Conscripts
A longitudinal, triple-blinded, randomized, placebo-controlled trial, with a 7-month follow-up period is conducted between October 2016 to April 2017.
- Trial name
- NCT04359524
- Testing
- Vitamin D3 (1200 IU/30µg)
- Where
- Estonia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Leho Rips
Growth Disorders, Malnutrition, Fetal
Evolutionary Nutrition Pilot: Enhancing Fetal Growth and Brain Development
Globally, 250 million children do not reach their developmental potential and 155 million are stunted, yet few population-based studies have examined the direct effects of nutrient deficiencies on early brain development.
- Conditions
- Growth Disorders, Malnutrition, Fetal, Stunting, Development; Delayed, Malnutrition
- Trial name
- NCT05242224
- Testing
- Evolutionary Nutrition Package
- Where
- Ecuador
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Iron Deficiency
Iron Absorption From Iron-fortified Fonio Porridge: a Stable Isotope Study
The study sought to investigate the effect of lowering phytic acid in fonio porridge with phytase activity naturally occurring in wheat flour on iron absorption using labelled stable isotopes of iron.
- Trial name
- NCT01443832
- Testing
- Fe57 and Fe58-FeSO4 stable isotopes
- Where
- Benin
- Volunteers
- 16 people
- Sponsor
- Wageningen University
Amyotrophic Lateral Sclerosis, ALS
Multicenter ALS Imaging Study
This is a multi-site study of ALS participants and healthy controls who will undergo brain and cervical spine MRIs and NfL blood testing at up-to 4 time points over the course of a year.
- Trial name
- NCT06735014
- Testing
- Magnetic Resonance Imaging, Plasma neurofilament light chain (NfL) quantification
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Vitamin D Deficiency, Respiratory Tract Infections
Vitamin D Supplementation for the Prevention of Acute Respiratory Infections: a RCT in Young Finnish Men
Vitamin D intervention effects on the prevention of acute respiratory tract infections among Young Finnish Men
- Trial name
- NCT05014048
- Testing
- Vitamin D3
- Where
- Finland
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Tampere University
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Severe Acute Malnutrition
Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
The primary outcome of the study is to identify gastrointestinal tolerance of under-five children with severe acute malnutrition to ready-to-drink high energy (1.5 kcal/ml) and standard energy (1 kcal/ml) oral nutrition…
- Trial name
- NCT04715204
- Testing
- High Energy Oral Nutrition Supplement, Standard Energy Oral Nutrition Supplement, Formula-75/Formula-100
- Where
- 2 sites in Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Vitamin D Deficiency Disease
Vitamin D Supplementation in Warfighters
A genomics-based approach will target specific genes that may explain the response in biomarkers and symptoms before and after supplementation.
- Trial name
- NCT02954549
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Fecal Microbiota Transplantation
Metabonomics of COPD and Transplanting of Faecal Bacteria in the Treatment of Its Malnutrition
Oxidative stress can affect the balance of intestinal flora and intestinal structure of patients, resulting in intestinal flora disorder.
- Trial name
- NCT04861649
- Testing
- fecal microbiota transplantation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Asclepius Meditec Inc.
Heart Failure, Acidosis, Lactic
Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery
The objective of this study is to determine whether preoperative parenteral thiamin supplementation does prevent the intra and early postoperative increase of lactate and whether this effect is related to the extent of thiamine…
- Conditions
- Heart Failure, Acidosis, Lactic, Thiamine Deficiency
- Trial name
- NCT01524315
- Testing
- Vitamin B1-ratiopharm
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Amyotrophic Lateral Sclerosis
Fecal Microbiota Transplantation Effect on Amyotrophic Lateral Sclerosis Patients
Given the role of adaptive immunity in ALS, the pathogenicity of some clostridial strains on motorneurons, the putative role of cyanobacteria in ALS development, and the increasing interest for microbiota in neurodegenerative…
- Trial name
- FETR-ALS (NCT03766321)
- Testing
- Fecal microbiota transplantation
- Where
- 5 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Frontotemporal Dementia (FTD), Amyotrophic Lateral Sclerosis (ALS)
[18F]ACI-19626 PET in TDP-43 Proteinopathies
The goal of this clinical trial is to test whether we can reliably and safely measure the accumulation of pathological protein TDP-43 [involved in rare forms of dementia such as frontotemporal dementia (FTD) and in amyotrophic…
- Conditions
- Frontotemporal Dementia (FTD), Amyotrophic Lateral Sclerosis (ALS), TDP-43 Proteinopathies, Suspected Limbic Predominant Age-related TDP-43 Encephalopathy (LATE)
- Trial name
- NCT06891716
- Testing
- [18F]ACI-19626
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AC Immune SA
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